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Q6G670

- ALF1_STAAS

UniProt

Q6G670 - ALF1_STAAS

Protein

Fructose-bisphosphate aldolase class 1

Gene

fda

Organism
Staphylococcus aureus (strain MSSA476)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 65 (01 Oct 2014)
      Sequence version 3 (23 Jan 2007)
      Previous versions | rss
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    Functioni

    Catalytic activityi

    D-fructose 1,6-bisphosphate = glycerone phosphate + D-glyceraldehyde 3-phosphate.UniRule annotation

    Pathwayi

    Sites

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Active sitei175 – 1751Proton acceptorUniRule annotation
    Active sitei212 – 2121Schiff-base intermediate with dihydroxyacetone-PUniRule annotation

    GO - Molecular functioni

    1. fructose-bisphosphate aldolase activity Source: UniProtKB-HAMAP

    GO - Biological processi

    1. glycolytic process Source: UniProtKB-HAMAP

    Keywords - Molecular functioni

    Lyase

    Keywords - Biological processi

    Glycolysis

    Keywords - Ligandi

    Schiff base

    Enzyme and pathway databases

    UniPathwayiUPA00109; UER00183.

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Fructose-bisphosphate aldolase class 1UniRule annotation (EC:4.1.2.13UniRule annotation)
    Alternative name(s):
    Fructose-bisphosphate aldolase class I
    Short name:
    FBP aldolaseUniRule annotation
    Gene namesi
    Name:fdaUniRule annotation
    Ordered Locus Names:SAS2491
    OrganismiStaphylococcus aureus (strain MSSA476)
    Taxonomic identifieri282459 [NCBI]
    Taxonomic lineageiBacteriaFirmicutesBacilliBacillalesStaphylococcus
    ProteomesiUP000002201: Chromosome

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Initiator methioninei1 – 11RemovedBy similarity
    Chaini2 – 296295Fructose-bisphosphate aldolase class 1PRO_0000216907Add
    BLAST

    Proteomic databases

    PRIDEiQ6G670.

    Interactioni

    Protein-protein interaction databases

    STRINGi282459.SAS2491.

    Structurei

    3D structure databases

    ProteinModelPortaliQ6G670.
    SMRiQ6G670. Positions 1-294.
    ModBaseiSearch...
    MobiDBiSearch...

    Family & Domainsi

    Sequence similaritiesi

    Belongs to the class I fructose-bisphosphate aldolase family.UniRule annotation

    Phylogenomic databases

    eggNOGiCOG3588.
    HOGENOMiHOG000073502.
    KOiK01623.
    OMAiYTGDYLA.
    OrthoDBiEOG6M6JJT.

    Family and domain databases

    Gene3Di3.20.20.70. 1 hit.
    HAMAPiMF_00729. FBP_aldolase_1.
    InterProiIPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view]
    PfamiPF00274. Glycolytic. 1 hit.
    [Graphical view]

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6G670-1 [UniParc]FASTAAdd to Basket

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    MNKEQLEKMK NGKGFIAALD QSGGSTPKAL KEYGVNEDQY SNEDEMFQLV    50
    HDMRTRVVTS PSFSPDKILG AILFEQTMDR EVEGKYTADY LADKGVVPFL 100
    KVDKGLAEEQ NGVQLMKPID NLDSLLDRAN ERHIFGTKMR SNILELNEQG 150
    IKDVVEQQFE VAKQIIAKGL VPIIEPEVNI NAKDKAEIEK VLKAELKKGL 200
    DNLNADQLVM LKLTIPTEPN LYKELAEHPN VVRVVVLSGG YSREKANELL 250
    KDNAELIASF SRALASDLRA GQSKEEFDKA LGDAVESIYD ASVNKN 296
    Length:296
    Mass (Da):32,967
    Last modified:January 23, 2007 - v3
    Checksum:iC6D620FBD9F76E96
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571857 Genomic DNA. Translation: CAG44307.1.
    RefSeqiYP_044604.1. NC_002953.3.

    Genome annotation databases

    GeneIDi2864245.
    KEGGisas:SAS2491.
    PATRICi19554650. VBIStaAur96780_2594.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    BX571857 Genomic DNA. Translation: CAG44307.1 .
    RefSeqi YP_044604.1. NC_002953.3.

    3D structure databases

    ProteinModelPortali Q6G670.
    SMRi Q6G670. Positions 1-294.
    ModBasei Search...
    MobiDBi Search...

    Protein-protein interaction databases

    STRINGi 282459.SAS2491.

    Proteomic databases

    PRIDEi Q6G670.

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2864245.
    KEGGi sas:SAS2491.
    PATRICi 19554650. VBIStaAur96780_2594.

    Phylogenomic databases

    eggNOGi COG3588.
    HOGENOMi HOG000073502.
    KOi K01623.
    OMAi YTGDYLA.
    OrthoDBi EOG6M6JJT.

    Enzyme and pathway databases

    UniPathwayi UPA00109 ; UER00183 .

    Family and domain databases

    Gene3Di 3.20.20.70. 1 hit.
    HAMAPi MF_00729. FBP_aldolase_1.
    InterProi IPR013785. Aldolase_TIM.
    IPR000741. FBA_I.
    IPR023014. FBA_I_Gram+-type.
    [Graphical view ]
    Pfami PF00274. Glycolytic. 1 hit.
    [Graphical view ]
    ProtoNeti Search...

    Publicationsi

    1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
      Strain: MSSA476.

    Entry informationi

    Entry nameiALF1_STAAS
    AccessioniPrimary (citable) accession number: Q6G670
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: March 1, 2005
    Last sequence update: January 23, 2007
    Last modified: October 1, 2014
    This is version 65 of the entry and version 3 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programProkaryotic Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome

    Documents

    1. PATHWAY comments
      Index of metabolic and biosynthesis pathways
    2. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3