Reviewed, UniProtKB/Swiss-Prot Q6G5K3 (UBIG_BARHE)

Names and origin

Protein names

Recommended name:
    3-demethylubiquinone-9 3-methyltransferase
    EC=2.1.1.64
Alternative name(s):
    3,4-dihydroxy-5-hexaprenylbenzoate methyltransferase
      Short name=DHHB methyltransferase

Gene names

Name:	ubiG
Ordered Locus Names:	BH04020

Organism

Bartonella henselae (Rochalimaea henselae) [Complete proteome] [HAMAP]

Taxonomic identifier

38323 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	247 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	S-adenosyl-L-methionine + 3-demethylubiquinone-9 = S-adenosyl-L-homocysteine + ubiquinone-9. HAMAP MF_00472
Pathway	Cofactor biosynthesis; ubiquinone biosynthesis. HAMAP MF_00472
Sequence similarities	Belongs to the methyltransferase superfamily. UbiG/COQ3 family.

Ontologies

Keywords
Biological process	Ubiquinone biosynthesis
Ligand	S-adenosyl-L-methionine
Molecular function	Methyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	ubiquinone biosynthetic process Inferred from electronic annotation. Source: HAMAP
Molecular function	2-polyprenyl-6-methoxy-1,4-benzoquinone methyltransferase activity Inferred from electronic annotation. Source: InterPro 3-demethylubiquinone-9 3-O-methyltransferase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 247	247	3-demethylubiquinone-9 3-methyltransferase HAMAP MF_00472		PRO_0000193366

Sequences

	Sequence		Length	Mass (Da)
	Q6G5K3-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: E135826B535ACE3B	FASTA	247	27,985
	10 20 30 40 50 60 MINETRTTLD QSEVDHFSRI AAEWWNPHGK FRPLHQFNPT RLAYIREKIC LELHRDPVSL 70 80 90 100 110 120 KPFENLKILD IGCGGGLLCE PMARLGAMVV GADASQTNIE VAKIHAAQNG LSIDYRTTTA 130 140 150 160 170 180 EALATEGEQF DIILNMEVVE HVADVNLFIE ATAKMLKPQG LMFISTLNRT WKAWGLAIIG 190 200 210 220 230 240 AEYILRWLPK GTHNYKKFLK PRELKNLLLQ NALTVVDEIG VTYNPLNDSW NRSKDMNVNY LLLAKKS

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX897699 Genomic DNA. Translation: CAF27211.1.
RefSeq	YP_033242.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2864849.
GenomeReviews	Gene locus BH04020 in contig BX897699_GR.
KEGG	bhe:BH04020.
NMPDR	fig|283166.1.peg.370.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6G5K3.
OMA	Q6G5K3. IRDAACR.
Enzyme and pathway databases
BioCyc	BHEN283166:BH04020-MON.
BRENDA	2.1.1.64. 277357.
Family and domain databases
HAMAP	MF_00472. [Tree]
InterPro	IPR013216. Methyltransf_11. IPR010233. UbiG_MeTrfase. [Graphical view]
Pfam	PF08241. Methyltransf_11. 1 hit. [Graphical view]
TIGRFAMs	TIGR01983. UbiG. 1 hit.
ProtoNet	Search...

Entry information

Entry name

UBIG_BARHE

Accession

Primary (citable) accession number: Q6G5K3

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 4, 2005
Last sequence update:	July 19, 2004
Last modified:	June 16, 2009
This is version 30 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)