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Q6G5H6 (PNCB_BARHE) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nicotinate phosphoribosyltransferase

Short name=NAPRTase
EC=6.3.4.21
Gene names
Name:pncB
Ordered Locus Names:BH00910
OrganismBartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae) [Complete proteome] [HAMAP]
Taxonomic identifier283166 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Protein attributes

Sequence length434 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Catalyzes the synthesis of beta-nicotinate D-ribonucleotide from nicotinate and 5-phospho-D-ribose 1-phosphate at the expense of ATP By similarity. HAMAP-Rule MF_00570

Catalytic activity

Nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate + ATP + H2O = beta-nicotinate D-ribonucleotide + diphosphate + ADP + phosphate. HAMAP-Rule MF_00570

Pathway

Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate D-ribonucleotide from nicotinate: step 1/1. HAMAP-Rule MF_00570

Sequence similarities

Belongs to the NAPRTase family.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 434434Nicotinate phosphoribosyltransferase HAMAP-Rule MF_00570
PRO_1000146829

Sequences

Sequence LengthMass (Da)Tools
Q6G5H6 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: A6BBDEB1EA5FDB13

FASTA43450,421
        10         20         30         40         50         60 
MNHPDIARRV YNHTWKLDPI IRSLLDTDFY KLLMVQMIWG LYPNVNVTFS LINRSKTIRL 

        70         80         90        100        110        120 
ADDIDEMELR AQLDHALNLR FTKKEMIWLA GNTFYGRKQI FEPDFLQWLE NFQLPEYELT 

       130        140        150        160        170        180 
RKDGQYILHF HGPWTHSSMW EIPALSIISE LRSRAAMKKL DRFTLDVLYA RAKAKMWSKV 

       190        200        210        220        230        240 
ERLKKLPNIK ISDFGTRRRH SFLWQRWCVE ALKEGIGNSF TGTSNVLLAM DTDLEALGTN 

       250        260        270        280        290        300 
AHELPMVIAA LTNNDNELRK APYQVLQDWN RYYGGNLLIV LPDTFGTEAF LRNAPDWVAD 

       310        320        330        340        350        360 
WTGFRPDSAP PLEGGERIIQ WWREKGKDPR EKLLIFSDAL DIDTIEKTYH HFHGKVRMSF 

       370        380        390        400        410        420 
GWGTDLTNDF VGCSPQETAT FDALSLVCKV THANGRPAVK LSDNPEKTIG NPQEIQRYLN 

       430 
FFGNENRVAK PIKT 

« Hide

References

[1]"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae."
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX897699 Genomic DNA. Translation: CAF26907.1.
RefSeqYP_032954.1. NC_005956.1.

3D structure databases

ProteinModelPortalQ6G5H6.
SMRQ6G5H6. Positions 1-426.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING283166.BH00910.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAF26907; CAF26907; BH00910.
GeneID2865455.
KEGGbhe:BH00910.
PATRIC20543893. VBIBarHen29080_0107.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1488.
HOGENOMHOG000284929.
KOK00763.
OMAQAVFHRY.
OrthoDBEOG6X10XB.

Enzyme and pathway databases

BioCycBHEN283166:GIVZ-91-MONOMER.
UniPathwayUPA00253; UER00457.

Family and domain databases

HAMAPMF_00570. NAPRTase.
InterProIPR006406. Nic_PRibTrfase.
IPR007229. Nic_PRibTrfase-Fam.
IPR002638. Quinolinate_PRibosylTrfase_C.
[Graphical view]
PANTHERPTHR11098:SF1. PTHR11098:SF1. 1 hit.
PfamPF04095. NAPRTase. 1 hit.
[Graphical view]
PIRSFPIRSF000484. NAPRT. 1 hit.
SUPFAMSSF51690. SSF51690. 1 hit.
TIGRFAMsTIGR01514. NAPRTase. 1 hit.
ProtoNetSearch...

Entry information

Entry namePNCB_BARHE
AccessionPrimary (citable) accession number: Q6G5H6
Entry history
Integrated into UniProtKB/Swiss-Prot: July 28, 2009
Last sequence update: July 19, 2004
Last modified: May 14, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways