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Q6G5G6 (PSD_BARHE) Reviewed, UniProtKB/Swiss-Prot

Last modified January 25, 2012. Version 40. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Phosphatidylserine decarboxylase proenzyme
EC=4.1.1.65

Cleaved into the following 2 chains:

  1. Phosphatidylserine decarboxylase alpha chain
  2. Phosphatidylserine decarboxylase beta chain
Gene names
Name:psd
Synonyms:psdA
Ordered Locus Names:BH05210
OrganismBartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae) [Complete proteome] [HAMAP]
Taxonomic identifier283166 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length232 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664

Cofactor

Pyruvoyl group By similarity. HAMAP MF_00664

Pathway

Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664

Sequence similarities

Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
   Biological processPhospholipid biosynthesis
   LigandPyruvate
   Molecular functionDecarboxylase
Lyase
   PTMZymogen
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphatidylethanolamine biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Molecular functioncofactor binding

Inferred from electronic annotation. Source: InterPro

phosphatidylserine decarboxylase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 189189Phosphatidylserine decarboxylase beta chain By similarity
PRO_0000029753
Chain190 – 23243Phosphatidylserine decarboxylase alpha chain By similarity
PRO_0000029754

Sites

Site189 – 1902Cleavage (non-hydrolytic) By similarity

Amino acid modifications

Modified residue1901Pyruvic acid (Ser) By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6G5G6 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: A9A0E4E584E3BB42

FASTA23225,948
        10         20         30         40         50         60 
MSILQSVHNS FAPIHKEGYP FIIAFFVISL ILGWVWSPLF WCGLVLTVWC IYFFRDPERV 

        70         80         90        100        110        120 
IPLNPNWIIS PADGRISFVG PCIPPEELGL GNAEMIRISV FMDIFSCHIN RVPISGKVES 

       130        140        150        160        170        180 
IIYHPGQFAN AELDKASQFN ERNGVVIDSK HGKIGVVQIA GAIARRIVCW SQEDDSVVTG 

       190        200        210        220        230 
QRFGLIRFGS RLDIYIPNEV KLRVTVGQTS IAGETVLGSF DDKSATTEFR FD

« Hide

References

[1]"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae."
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX897699 Genomic DNA. Translation: CAF27329.1.
RefSeqYP_033357.1. NC_005956.1.

3D structure databases

ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2865535.
GenomeReviewsGene locus BH05210 in contig BX897699_GR.
KEGGbhe:BH05210.
NMPDRfig|283166.1.peg.485.
PATRIC20544829. VBIBarHen29080_0567.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG541103.
OMAIFMSVFN.
PhylomeDBQ6G5G6.
ProtClustDBPRK05305.

Enzyme and pathway databases

BioCycBHEN283166:BH05210-MONOMER.

Family and domain databases

HAMAPMF_00664. PS_decarb_type3.
[Tree]
InterProIPR003817. PS_Dcarbxylase.
IPR004428. PtdSer_deCO2ase-related.
[Graphical view]
KOK01613.
PfamPF02666. PS_Dcarbxylase. 1 hit.
[Graphical view]
TIGRFAMsTIGR00164. PS_decarb_rel. 1 hit.
ProtoNetSearch...

Entry information

Entry namePSD_BARHE
AccessionPrimary (citable) accession number: Q6G5G6
Entry history
Integrated into UniProtKB/Swiss-Prot: February 1, 2005
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 40 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

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