Q6G5F0DEF_BARHEPeptide deformylasePDF3.5.1.88Polypeptide deformylasedefBH00760Bartonella henselae (strain ATCC 49882 / DSM 28221 / CCUG 30454 / Houston 1)Rochalimaea henselaeBacteriaPseudomonadotaAlphaproteobacteriaHyphomicrobialesBartonellaceaeBartonellaThe louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae.NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions.H2O + N-terminal N-formyl-L-methionyl-[peptide] = formate + N-terminal L-methionyl-[peptide]Fe(2+)Binds 1 Fe(2+) ion.Belongs to the polypeptide deformylase family.HydrolaseIronMetal-bindingProtein biosynthesisFe cationFe cationFe cationMPMRPLVIVPDPILREISKPVEYIDSAVQKLADDMLETMYHAQGVGLAAIQIGIPLRMLVLDVSRNDEQKNPLVIINPEVLWLSDERNIYKEGCLSIPEYFAEVERPKRLCVRYQNREGKQTEIEADDLLATCLQHEIDHLNGRLFIDYLSKIKRDMVIRKFKKRAKEKNTQEAVL
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