ID   COAE_BARHE              Reviewed;         195 AA.
AC   Q6G5A8;
DT   16-AUG-2004, integrated into UniProtKB/Swiss-Prot.
DT   19-JUL-2004, sequence version 1.
DT   16-JUN-2009, entry version 34.
DE   RecName: Full=Dephospho-CoA kinase;
DE            EC=2.7.1.24;
DE   AltName: Full=Dephosphocoenzyme A kinase;
GN   Name=coaE; OrderedLocusNames=BH00040;
OS   Bartonella henselae (Rochalimaea henselae).
OC   Bacteria; Proteobacteria; Alphaproteobacteria; Rhizobiales;
OC   Bartonellaceae; Bartonella.
OX   NCBI_TaxID=38323;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 49882 / Houston 1;
RX   PubMed=15210978; DOI=10.1073/pnas.0305659101;
RA   Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H.,
RA   Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M.,
RA   La Scola B., Holmberg M., Andersson S.G.E.;
RT   "The louse-borne human pathogen Bartonella quintana is a genomic
RT   derivative of the zoonotic agent Bartonella henselae.";
RL   Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004).
CC   -!- FUNCTION: Catalyzes the phosphorylation of the 3'-hydroxyl group
CC       of dephosphocoenzyme A to form coenzyme A (By similarity).
CC   -!- CATALYTIC ACTIVITY: ATP + 3'-dephospho-CoA = ADP + CoA.
CC   -!- PATHWAY: Cofactor biosynthesis; coenzyme A biosynthesis; coenzyme
CC       A from pantothenate: step 5/5.
CC   -!- SUBCELLULAR LOCATION: Cytoplasm (By similarity).
CC   -!- SIMILARITY: Belongs to the coaE family.
CC   -!- SIMILARITY: Contains 1 DPCK (dephospho-CoA kinase) domain.
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DR   EMBL; BX897699; CAF26820.1; -; Genomic_DNA.
DR   RefSeq; YP_032876.1; -.
DR   GeneID; 2865422; -.
DR   GenomeReviews; BX897699_GR; BH00040.
DR   KEGG; bhe:BH00040; -.
DR   NMPDR; fig|283166.1.peg.4; -.
DR   HOGENOM; Q6G5A8; -.
DR   OMA; Q6G5A8; RIIEEQY.
DR   BioCyc; BHEN283166:BH00040-MON; -.
DR   BRENDA; 2.7.1.24; 277357.
DR   GO; GO:0005737; C:cytoplasm; IEA:UniProtKB-SubCell.
DR   GO; GO:0005524; F:ATP binding; IEA:HAMAP.
DR   GO; GO:0004140; F:dephospho-CoA kinase activity; IEA:HAMAP.
DR   GO; GO:0015937; P:coenzyme A biosynthetic process; IEA:HAMAP.
DR   HAMAP; MF_00376; -; 1.
DR   InterPro; IPR001977; Depp_CoAkinase.
DR   PANTHER; PTHR10695; Depp_CoAkinase; 1.
DR   Pfam; PF01121; CoaE; 1.
DR   ProDom; PD003329; Depp_CoAkinase; 1.
DR   TIGRFAMs; TIGR00152; Depp_CoAkinase; 1.
DR   PROSITE; PS51219; DPCK; 1.
PE   3: Inferred from homology;
KW   ATP-binding; Coenzyme A biosynthesis; Complete proteome; Cytoplasm;
KW   Kinase; Nucleotide-binding; Transferase.
FT   CHAIN         1    195       Dephospho-CoA kinase.
FT                                /FTId=PRO_0000172908.
FT   DOMAIN        3    195       DPCK.
FT   NP_BIND       8     15       ATP (Potential).
SQ   SEQUENCE   195 AA;  22146 MW;  F40B45E26055BAE8 CRC64;
     MKIIGLTGSI AMGKSTVADF FRQAGISVFS ADEAVYKLYK SEPTLSLIEY KFPGVFENGK
     VNRQKLSEIL INDNEKLQTL EKIIHPLVQE KEKKFIDTAR QQGEKLVVLD IPLLLETKGE
     KRVDSVVVVS APLAIQKERA MIRQNMSEKK FAFINGRQMS DEKKRARADF IIDTGKDLEN
     TREQVLFVIK SLLKN
//