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Q6G4D2 (EX7S_BARHE) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Exodeoxyribonuclease 7 small subunit

EC=3.1.11.6
Alternative name(s):
Exodeoxyribonuclease VII small subunit
Short name=Exonuclease VII small subunit
Gene names
Name:xseB
Ordered Locus Names:BH04340
OrganismBartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae) [Complete proteome] [HAMAP]
Taxonomic identifier283166 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Protein attributes

Sequence length84 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Bidirectionally degrades single-stranded DNA into large acid-insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides By similarity. HAMAP-Rule MF_00337

Catalytic activity

Exonucleolytic cleavage in either 5'- to 3'- or 3'- to 5'-direction to yield nucleoside 5'-phosphates. HAMAP-Rule MF_00337

Subunit structure

Heterooligomer composed of large and small subunits By similarity.

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00337.

Sequence similarities

Belongs to the XseB family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionExonuclease
Hydrolase
Nuclease
   Technical termComplete proteome
Gene Ontology (GO)
   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

exodeoxyribonuclease VII complex

Inferred from electronic annotation. Source: InterPro

   Molecular_functionexodeoxyribonuclease VII activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 8484Exodeoxyribonuclease 7 small subunit HAMAP-Rule MF_00337
PRO_0000206922

Sequences

Sequence LengthMass (Da)Tools
Q6G4D2 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 058630C4496357B0

FASTA849,349
        10         20         30         40         50         60 
MKQEIQKGDV ATLSFEQALK QLEVIVENLE RGDVPLEQSI DIYERGEALK KHCEKLLKAA 

        70         80 
EAKVEKIQLS EGGTPEGVEP LDSE 

« Hide

References

[1]"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae."
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX897699 Genomic DNA. Translation: CAF27243.1.
RefSeqYP_033272.1. NC_005956.1.

3D structure databases

ProteinModelPortalQ6G4D2.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING283166.BH04340.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAF27243; CAF27243; BH04340.
GeneID2865834.
KEGGbhe:BH04340.
PATRIC20544643. VBIBarHen29080_0475.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG1722.
HOGENOMHOG000228798.
KOK03602.
OMAKKHCEKL.
OrthoDBEOG69KV31.
ProtClustDBPRK00977.

Enzyme and pathway databases

BioCycBHEN283166:GIVZ-434-MONOMER.

Family and domain databases

Gene3D1.10.287.1040. 1 hit.
HAMAPMF_00337. Exonuc_7_S.
InterProIPR003761. Exonuc_VII_S.
[Graphical view]
PfamPF02609. Exonuc_VII_S. 1 hit.
[Graphical view]
PIRSFPIRSF006488. Exonuc_VII_S. 1 hit.
ProDomPD028235. Exonuc_VII_S. 1 hit.
[Graphical view] [Entries sharing at least one domain]
TIGRFAMsTIGR01280. xseB. 1 hit.
ProtoNetSearch...

Entry information

Entry nameEX7S_BARHE
AccessionPrimary (citable) accession number: Q6G4D2
Entry history
Integrated into UniProtKB/Swiss-Prot: June 7, 2005
Last sequence update: July 19, 2004
Last modified: April 16, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families