Reviewed, UniProtKB/Swiss-Prot Q6G3V6 (RPIA_BARHE)

Names and origin

Protein names

Recommended name:
    Ribose-5-phosphate isomerase A
    EC=5.3.1.6
Alternative name(s):
    Phosphoriboisomerase A
      Short name=PRI

Gene names

Name:	rpiA
Ordered Locus Names:	BH06410

Organism

Bartonella henselae (Rochalimaea henselae) [Complete proteome] [HAMAP]

Taxonomic identifier

38323 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	234 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Evidence at protein level.

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate. HAMAP MF_00170
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1. HAMAP MF_00170
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Molecular function	Isomerase
Technical term	3D-structure Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: HAMAP
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

Feature key

Position(s)

Length

Description

Graphical view

Feature identifier

Molecule processing

Chain

1 – 234

234

Ribose-5-phosphate isomerase A HAMAP MF_00170

PRO_0000158388

Secondary structure

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234

Helix Strand Turn

Details...

Helix

3 – 15

13

Beta strand

22 – 24

3

Helix

31 – 38

8

Turn

42 – 44

3

Beta strand

49 – 51

3

Helix

56 – 65

10

Turn

72 – 74

3

Beta strand

77 – 79

3

Beta strand

81 – 83

3

Helix

102 – 110

9

Beta strand

115 – 120

6

Helix

121 – 123

3

Beta strand

133 – 137

5

Helix

143 – 155

13

Beta strand

162 – 164

3

Beta strand

179 – 183

5

Helix

191 – 199

9

Beta strand

216 – 220

5

Beta strand

226 – 229

4

Helix

231 – 233

3

Sequences

	Sequence		Length	Mass (Da)
	Q6G3V6-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: D122B2390A42511E	FASTA	234	25,161
	10 20 30 40 50 60 MNVQQLKKMA ALKALEFVED DMRLGIGSGS TVNEFIPLLG ERVANGLRVT CVATSQYSEQ 70 80 90 100 110 120 LCHKFGVPIS TLEKIPELDL DIDGADEIGP EMTLIKGGGG ALLHEKIVAS ASRAMFVIAD 130 140 150 160 170 180 ETKMVKTLGA FALPIEVNPF GIHATRIAIE KAADNLGLSG EITLRMNGDD PFKTDGGHFI 190 200 210 220 230 FDAFWGRILQ PKLLSEALLA IPGVVEHGLF LGLASRAIVA MADSQIKVLE PFDF

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases

EMBLGenBankDDBJ

BX897699 Genomic DNA. Translation: CAF27445.1.

RefSeq

YP_033470.1.

3D structure databases

PDBPDBe

Entry	Method	Resolution (Å)	Chain	Positions	PDBsum
3HHE	X-ray	2.30	A/B	1-234	[»]

ModBase

Search...

Genome annotation databases

GeneID

2865998.

GenomeReviews

Gene locus BH06410 in contig BX897699_GR.

KEGG

bhe:BH06410.

NMPDR

fig|283166.1.peg.598.

Organism-specific databases

CMR

Search...

Phylogenomic databases

HOGENOM

Q6G3V6.

OMA

QEKIVAT.

Enzyme and pathway databases

BioCyc

BHEN283166:BH06410-MON.

BRENDA

5.3.1.6. 277357.

Family and domain databases

HAMAP

MF_00170.
[Tree]

InterPro

IPR014036. HTH_DeoR.
IPR004788. RpiA.
[Graphical view]

PANTHER

PTHR11934. RpiA. 1 hit.

Pfam

PF00455. DeoR. 1 hit.
PF06026. Rib_5-P_isom_A. 1 hit.
[Graphical view]

ProDom

PD005813. RpiA. 1 hit.
[Graphical view] [Entries sharing at least one domain]

TIGRFAMs

TIGR00021. rpiA. 1 hit.

ProtoNet

Search...

Entry information

Entry name

RPIA_BARHE

Accession

Primary (citable) accession number: Q6G3V6

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 7, 2005
Last sequence update:	July 19, 2004
Last modified:	November 3, 2009
This is version 33 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)