Reviewed, UniProtKB/Swiss-Prot Q6G3D5 (MURI_BARHE)

Names and origin

Protein names

Recommended name:
    Glutamate racemase
    EC=5.1.1.3

Gene names

Name:	murI
Ordered Locus Names:	BH08380

Organism

Bartonella henselae (Rochalimaea henselae) [Complete proteome] [HAMAP]

Taxonomic identifier

38323 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	270 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Provides the (R)-glutamate required for cell wall biosynthesis By similarity. HAMAP MF_00258
Catalytic activity	L-glutamate = D-glutamate. HAMAP MF_00258
Pathway	Cell wall biogenesis; peptidoglycan biosynthesis. HAMAP MF_00258
Sequence similarities	Belongs to the aspartate/glutamate racemases family.

Ontologies

Keywords
Biological process	Cell shape Cell wall biogenesis/degradation Peptidoglycan synthesis
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	cellular cell wall organization Inferred from electronic annotation. Source: UniProtKB-KW peptidoglycan biosynthetic process Inferred from electronic annotation. Source: HAMAP regulation of cell shape Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	glutamate racemase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 270	270	Glutamate racemase HAMAP MF_00258		PRO_1000047546

Sequences

	Sequence		Length	Mass (Da)
	Q6G3D5-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 955FC61093DF33B1	FASTA	270	30,725
	10 20 30 40 50 60 MDERPVLFFD SGIGGLTVLR EVRSLIPEKQ FIYVADDVGF PYGNWEENVL KNRILKIFTN 70 80 90 100 110 120 LLTVYNPALC VIACNTVSTL MIADLRERFP HILFVGTVPA IKLAAEQTKS GFISVLATPG 130 140 150 160 170 180 TVKRTYTHEL INSFAGQCHV QLVGSEKLAG FAENYLRGQS VDLEELRNEI LPCFVKKNGK 190 200 210 220 230 240 HTDIIVLACT HYPFLLHFFR EQALWHVQWI DPSKAIAKRT RSLLPQRIHH QTVKKYEDFA 250 260 270 LFTSQNITSS TKRLLKEFSL NITKGVDFKV

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX897699 Genomic DNA. Translation: CAF27637.1.
RefSeq	YP_033644.1.
3D structure databases
SMR	Q6G3D5. Positions 1-257.
ModBase	Search...
Genome annotation databases
GeneID	2865368.
GenomeReviews	Gene locus BH08380 in contig BX897699_GR.
KEGG	bhe:BH08380.
NMPDR	fig|283166.1.peg.772.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG645102.
OMA	LPCPGLV.
PhylomeDB	Q6G3D5.
Enzyme and pathway databases
BioCyc	BHEN283166:BH08380-MONOMER.
BRENDA	5.1.1.3. 277357.
Family and domain databases
HAMAP	MF_00258. Glu_racemase. [Tree]
InterPro	IPR015942. Asp/Glu/hydantoin_racemase. IPR001920. Asp/Glu_race. IPR018187. Asp/Glu_racemase_AS. IPR004391. Glu_race. [Graphical view]
Gene3D	G3DSA:3.40.50.1860. Asp/Glu_race. 1 hit.
Pfam	PF01177. Asp_Glu_race. 1 hit. [Graphical view]
TIGRFAMs	TIGR00067. glut_race. 1 hit.
PROSITE	PS00923. ASP_GLU_RACEMASE_1. False negative. PS00924. ASP_GLU_RACEMASE_2. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

MURI_BARHE

Accession

Primary (citable) accession number: Q6G3D5

Entry history

Integrated into UniProtKB/Swiss-Prot:	January 15, 2008
Last sequence update:	July 19, 2004
Last modified:	February 9, 2010
This is version 38 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)