Reviewed, UniProtKB/Swiss-Prot Q6G316 (SYR_BARHE)

Names and origin

Protein names

Recommended name:
    Arginyl-tRNA synthetase
    EC=6.1.1.19
Alternative name(s):
    Arginine--tRNA ligase
      Short name=ArgRS

Gene names

Name:	argS
Ordered Locus Names:	BH09980

Organism

Bartonella henselae (Rochalimaea henselae) [Complete proteome] [HAMAP]

Taxonomic identifier

38323 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	585 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg). HAMAP MF_00123
Subunit structure	Monomer By similarity.
Subcellular location	Cytoplasm. HAMAP MF_00123
Sequence similarities	Belongs to the class-I aminoacyl-tRNA synthetase family.

Ontologies

Keywords
Biological process	Protein biosynthesis
Cellular component	Cytoplasm
Ligand	ATP-binding Nucleotide-binding
Molecular function	Aminoacyl-tRNA synthetase Ligase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	arginyl-tRNA aminoacylation Inferred from electronic annotation. Source: HAMAP
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ATP binding Inferred from electronic annotation. Source: HAMAP arginine-tRNA ligase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 585	585	Arginyl-tRNA synthetase HAMAP MF_00123		PRO_0000241988
Regions
	Motif	131 – 141	11	"HIGH" region HAMAP MF_00123

Sequences

	Sequence		Length	Mass (Da)
	Q6G316-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 0A069C7C8C5846BB	FASTA	585	66,328
	10 20 30 40 50 60 MNVFKNFEKK IKKSLESSDI KGKNGEDLDL SKITVDPPRD SSHGHLSTNA AMVLAKSTGL 70 80 90 100 110 120 NPRALAEKII ELLKNDPSVE SINVAGPGFI NIKLTKPFWQ DLIKSMLEKG ISYGRIPMGQ 130 140 150 160 170 180 GKRINVEYVS ANPTGPMHVG HCRGAVVGDV LSNLLQFVGY NITKEYYIND AGKQIEVLAH 190 200 210 220 230 240 SVLLRYREAL GQKINEIPEG LYPGEYLIPL GQSLAQEFGD KLLTIDKEEA LSIVKERAIH 250 260 270 280 290 300 EMMSMIRKDL AALNIYHDIF FSERMLYADN ARAIRNTIND LTLKGYIYKG KLPPPKGQNT 310 320 330 340 350 360 EDWEPCEQTL FRSTDVGDDQ DRVLIKSDGS YTYFAADVAY FRDKFNRHFD EMIYILGADH 370 380 390 400 410 420 AGYVKRLEAM AKAISNDKAK LSVFLCQLVK LFRNGHPVRM SKRAGSFVTL RDVVEEVGSD 430 440 450 460 470 480 PVRFMMLYRK CEAPLDFDFA KVTEQSKDNP IFYVQYASAR CHSVFRQAQE TLCIENISND 490 500 510 520 530 540 KIIEHLNRLT DDNEIFLIRK LSEYPRIIEQ AVVHKEPHRL AFYLYDLASS FHTHWNKGSD 550 560 570 580 NLNLRFIQPD DRNLSFARLG LIQAIMNILS SGLAIVGIKA ATEMR

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX897699 Genomic DNA. Translation: CAF27790.1.
RefSeq	YP_033784.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2866076.
GenomeReviews	Gene locus BH09980 in contig BX897699_GR.
KEGG	bhe:BH09980.
NMPDR	fig|283166.1.peg.912.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6G316.
OMA	ADHHGYV.
Enzyme and pathway databases
BioCyc	BHEN283166:BH09980-MON.
BRENDA	6.1.1.19. 277357.
Family and domain databases
HAMAP	MF_00123. [Tree]
InterPro	IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-synth_Ic. IPR015945. Arg-tRNA-synth_Ic_core. IPR005148. Arg-tRNA-synth_Ic_N. IPR008909. DALR_anticod_bd. IPR014729. Rossmann-like_a/b/a_fold. [Graphical view]
Gene3D	G3DSA:3.30.1360.70. Arg-tRNA-synth_Ic_N. 1 hit. G3DSA:3.40.50.620. Rossmann-like_a/b/a_fold. 1 hit.
PANTHER	PTHR11956. Arg_tRNA-synt_1c. 1 hit.
Pfam	PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 1 hit. [Graphical view]
PRINTS	PR01038. TRNASYNTHARG.
TIGRFAMs	TIGR00456. argS. 1 hit.
PROSITE	PS00178. AA_TRNA_LIGASE_I. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

SYR_BARHE

Accession

Primary (citable) accession number: Q6G316

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 27, 2006
Last sequence update:	July 19, 2004
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)