Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6G1W2

- SYL_BARHE

UniProt

Q6G1W2 - SYL_BARHE

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

Leucine--tRNA ligase

Gene

leuS

Organism
Bartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei641 – 6411ATPUniRule annotation

GO - Molecular functioni

  1. aminoacyl-tRNA editing activity Source: InterPro
  2. ATP binding Source: UniProtKB-HAMAP
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBHEN283166:GIVZ-1534-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligaseUniRule annotation (EC:6.1.1.4UniRule annotation)
Alternative name(s):
Leucyl-tRNA synthetaseUniRule annotation
Short name:
LeuRSUniRule annotation
Gene namesi
Name:leuSUniRule annotation
Ordered Locus Names:BH15390
OrganismiBartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae)
Taxonomic identifieri283166 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000000421: Chromosome

Subcellular locationi

Cytoplasm UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 880880Leucine--tRNA ligasePRO_0000151975Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi283166.BH15390.

Structurei

3D structure databases

ProteinModelPortaliQ6G1W2.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi49 – 5911"HIGH" regionAdd
BLAST
Motifi638 – 6425"KMSKS" region

Sequence similaritiesi

Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6G1W2-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MTIEHYNLGE RYNPRACERK WQAIWDEKKT FQTVQEDRRE KYYVLEMFPY
60 70 80 90 100
PSGRIHMGHV RNYAMGDVVA RYKRAKGFNV LHPMGWDAFG MPAENAAMQN
110 120 130 140 150
KVHPKTWTYQ NIAVMRGQLK QLGLSVDWSR EFATCDVDYY HRQQMLFLDF
160 170 180 190 200
YQKGLVARKV AKVNWDPVDQ TVLANEQVVD GRGWRSGALV EQRELTQWFF
210 220 230 240 250
KISDFSEDLL AGLEELEQWP EKVRIMQKNW IGKSQGLLIR WALKSTEEAD
260 270 280 290 300
EVCKSFDEVV CYSTRPDTLF GASFLALSVD HPLAQALAQK DKALEFFIEN
310 320 330 340 350
CRSGGTTTAE LETAEKQGFR TSLVAVHPFD VAVHIPVYIA NFVLMDYGTG
360 370 380 390 400
AVFGCPAHDQ RDFDFARKYD LPVQPVVLPS GVEREDFAIT ETPYLGDGVM
410 420 430 440 450
INSSFLDGLT PQQAFEEAAK RLEGQMLNGK PQAEKTVQFR LRDWGISRQR
460 470 480 490 500
YWGCPIPMIH CTSCGVVPVP RADLPVVLPD DVTFEQPGNP LVCHETWKSV
510 520 530 540 550
ACPVCGQFAK RETDTMDTFV DSSWYYARFT APFAQEPVDK KATTEWLPVQ
560 570 580 590 600
QYIGGIEHAI LHLLYARFFT RAMKSMGYVT VDEPFKGLFT QGMVVHETYR
610 620 630 640 650
DEKDWVSPEE ISIVEKDGKR QAYKLTDQSE VTIGSIEKMS KSKKNVVDPD
660 670 680 690 700
DIIASYGADT VRWFILSDSP PERDVIWTES GVEGAHRFVQ RVWRCVALSA
710 720 730 740 750
PVLRDVVPCV GKQGAALQLS KVAHRTLYAV EDDLEKFAFN RAIARLYEFL
760 770 780 790 800
NIMAPLLNRI ENVEDEMKAA LRQAMDFFLA MIAPIMPHLA EECHAALGEK
810 820 830 840 850
TLISELAWPV CDRALTVEEC YTLPVQINGK KRGEVTVAAT ASEAMIEEAV
860 870 880
LALDFVKVHL VKKPVKKMII VPKRIVNVVL
Length:880
Mass (Da):100,077
Last modified:July 19, 2004 - v1
Checksum:i5589AC710AB5F1B8
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897699 Genomic DNA. Translation: CAF28302.1.
RefSeqiWP_011181305.1. NC_005956.1.
YP_034235.1. NC_005956.1.

Genome annotation databases

EnsemblBacteriaiCAF28302; CAF28302; BH15390.
GeneIDi2865580.
KEGGibhe:BH15390.
PATRICi20547354. VBIBarHen29080_1785.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897699 Genomic DNA. Translation: CAF28302.1 .
RefSeqi WP_011181305.1. NC_005956.1.
YP_034235.1. NC_005956.1.

3D structure databases

ProteinModelPortali Q6G1W2.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 283166.BH15390.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF28302 ; CAF28302 ; BH15390 .
GeneIDi 2865580.
KEGGi bhe:BH15390.
PATRICi 20547354. VBIBarHen29080_1785.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci BHEN283166:GIVZ-1534-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 49882 / Houston 1.

Entry informationi

Entry nameiSYL_BARHE
AccessioniPrimary (citable) accession number: Q6G1W2
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: July 19, 2004
Last modified: October 29, 2014
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3