Q6G1R3 (GCP_BARHE) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp

Alternative name(s):
t(6)A37 threonylcarbamoyladenosine biosynthesis protein

Gene names

Name:	gcp
Ordered Locus Names:	BH16110

Organism

Bartonella henselae (strain ATCC 49882 / Houston 1) (Rochalimaea henselae) [Complete proteome] [HAMAP]

Taxonomic identifier

283166 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	364 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Function	Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t6A37) in tRNAs that read codons beginning with adenine By similarity. HAMAP MF_01445
Subcellular location	Cytoplasm Potential HAMAP MF_01445.
Sequence similarities	Belongs to the KAE1 / YgjD family.

Ontologies

Keywords
Biological process	tRNA processing
Cellular component	Cytoplasm
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	proteolysis Inferred from electronic annotation. Source: InterPro tRNA processing Inferred from electronic annotation. Source: UniProtKB-KW
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	metalloendopeptidase activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 364	364	Probable tRNA threonylcarbamoyladenosine biosynthesis protein Gcp HAMAP MF_01445		PRO_0000303276

Sequences

	Sequence		Length	Mass (Da)
	Q6G1R3 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 7D9006CCF3594489	FASTA	364	38,596
	10 20 30 40 50 60 MRLLGIETSC DETATAVIEH TIGGNSQILS NIVWSQTDHH APYGGVVPEI AARAHVEILD 70 80 90 100 110 120 ELILKALRDA HTKLKDIDAI AVTNGPGLIG GLLVGVMSAK ALSLATGKPF IGVNHLEGHA 130 140 150 160 170 180 LTAVLTHNVH FPYLLLLVSG GHTQTILVHG VGNYQRLGTT IDDALGEAFD KTAKLLGLPY 190 200 210 220 230 240 PGGPAIEKAA LLGNKNRIPL PRPLKGEKRL DFSFSGLKTA VRQAATAISP LTESDVADIA 250 260 270 280 290 300 ASFQAAVTDT VYDRVYLALQ HFTQQYPLSR HQGPRPPALV VAGGVAANQA IRLTLQELAD 310 320 330 340 350 360 QQGFEFIAPP LSLCTDNAAM IAFAGAQRLA RGEKSSLDIA PRSRWPLDEK SAPLIGTGRR GTKA

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 49882 / Houston 1.

Cross-references

Sequence databases
EMBL GenBank DDBJ	BX897699 Genomic DNA. Translation: CAF28374.1.
RefSeq	YP_034304.1. NC_005956.1.
3D structure databases
ProteinModelPortal	Q6G1R3.
ModBase	Search...
Protein family/group databases
MEROPS	M22.001.
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2864654.
GenomeReviews	Gene locus BH16110 in contig BX897699_GR.
KEGG	bhe:BH16110.
NMPDR	fig|283166.1.peg.1432.
PATRIC	20547528. VBIBarHen29080_1872.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	HBG304663.
OMA	PLYGVNH.
PhylomeDB	Q6G1R3.
ProtClustDB	PRK09604.
Enzyme and pathway databases
BioCyc	BHEN283166:BH16110-MONOMER.
Family and domain databases
HAMAP	MF_01445. gcp. [Tree]
InterPro	IPR022450. Pept_M22_O-sialoglycopept. IPR000905. Peptidase_M22. IPR017861. Peptidase_M22_subgr. [Graphical view]
KO	K01409.
Pfam	PF00814. Peptidase_M22. 1 hit. [Graphical view]
PRINTS	PR00789. OSIALOPTASE.
TIGRFAMs	TIGR03723. Bact_gcp. 1 hit. TIGR00329. Gcp_kae1. 1 hit.
PROSITE	PS01016. GLYCOPROTEASE. False negative. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GCP_BARHE

Accession

Primary (citable) accession number: Q6G1R3

Entry history

Integrated into UniProtKB/Swiss-Prot:	September 11, 2007
Last sequence update:	July 19, 2004
Last modified:	January 25, 2012
This is version 47 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Prokaryotic Protein Annotation Program