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Protein

Ribosomal RNA small subunit methyltransferase G

Gene

rsmG

Organism
Bartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) (Rochalimaea henselae)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Specifically methylates the N7 position of guanine in position 527 of 16S rRNA.UniRule annotation

Catalytic activityi

S-adenosyl-L-methionine + guanine(527) in 16S rRNA = S-adenosyl-L-homocysteine + N(7)-methylguanine(527) in 16S rRNA.UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei77 – 771S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei82 – 821S-adenosyl-L-methionine; via carbonyl oxygenUniRule annotation
Binding sitei146 – 1461S-adenosyl-L-methionineUniRule annotation

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Methyltransferase, Transferase

Keywords - Biological processi

rRNA processing

Keywords - Ligandi

S-adenosyl-L-methionine

Enzyme and pathway databases

BioCyciBHEN283166:GIVZ-1663-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Ribosomal RNA small subunit methyltransferase GUniRule annotation (EC:2.1.1.170UniRule annotation)
Alternative name(s):
16S rRNA 7-methylguanosine methyltransferaseUniRule annotation
Short name:
16S rRNA m7G methyltransferaseUniRule annotation
Gene namesi
Name:rsmGUniRule annotation
Ordered Locus Names:BH16670
OrganismiBartonella henselae (strain ATCC 49882 / DSM 28221 / Houston 1) (Rochalimaea henselae)
Taxonomic identifieri283166 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
Proteomesi
  • UP000000421 Componenti: Chromosome

Subcellular locationi

  • Cytoplasm UniRule annotation

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 215215Ribosomal RNA small subunit methyltransferase GPRO_0000184218Add
BLAST

Proteomic databases

PaxDbiQ6G1L0.

Interactioni

Protein-protein interaction databases

STRINGi283166.BH16670.

Structurei

3D structure databases

ProteinModelPortaliQ6G1L0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Regioni130 – 1312S-adenosyl-L-methionine bindingUniRule annotation

Sequence similaritiesi

Belongs to the methyltransferase superfamily. RNA methyltransferase RsmG family.UniRule annotation

Phylogenomic databases

eggNOGiENOG4107YTN. Bacteria.
COG0357. LUCA.
HOGENOMiHOG000221015.
KOiK03501.
OMAiSAQIFQL.
OrthoDBiPOG091H00IF.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G. 1 hit.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. rsmG_gidB. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6G1L0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDFSIEQKYQ ELLKIISSVS RETMQDLMHF ESLIIQWNKH INLISSSTIP
60 70 80 90 100
LLWTRHILDS AQIYPLHSDL LHWCDLGSGG GFPAIVIAIF MKEKKTGHID
110 120 130 140 150
LVESNGKKVA FLRTVIAQLD LPATVYHCRI EDVTQKIKNP EVITARGLAC
160 170 180 190 200
LDDLLRLIFP LLTQKTIALL QKGRDYSKEI KNASANWQFD LLKHKSKIDE
210
NSVILEISQV RSFRG
Length:215
Mass (Da):24,566
Last modified:July 19, 2004 - v1
Checksum:iB4EFCB3BFE68D2BE
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897699 Genomic DNA. Translation: CAF28428.1.
RefSeqiWP_011181427.1. NZ_LRIJ01000002.1.

Genome annotation databases

EnsemblBacteriaiCAF28428; CAF28428; BH16670.
KEGGibhe:BH16670.
PATRICi20547660. VBIBarHen29080_1937.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BX897699 Genomic DNA. Translation: CAF28428.1.
RefSeqiWP_011181427.1. NZ_LRIJ01000002.1.

3D structure databases

ProteinModelPortaliQ6G1L0.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi283166.BH16670.

Proteomic databases

PaxDbiQ6G1L0.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaiCAF28428; CAF28428; BH16670.
KEGGibhe:BH16670.
PATRICi20547660. VBIBarHen29080_1937.

Phylogenomic databases

eggNOGiENOG4107YTN. Bacteria.
COG0357. LUCA.
HOGENOMiHOG000221015.
KOiK03501.
OMAiSAQIFQL.
OrthoDBiPOG091H00IF.

Enzyme and pathway databases

BioCyciBHEN283166:GIVZ-1663-MONOMER.

Family and domain databases

Gene3Di3.40.50.150. 1 hit.
HAMAPiMF_00074. 16SrRNA_methyltr_G. 1 hit.
InterProiIPR003682. rRNA_ssu_MeTfrase_G.
IPR029063. SAM-dependent_MTases.
[Graphical view]
PfamiPF02527. GidB. 1 hit.
[Graphical view]
PIRSFiPIRSF003078. GidB. 1 hit.
SUPFAMiSSF53335. SSF53335. 1 hit.
TIGRFAMsiTIGR00138. rsmG_gidB. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiRSMG_BARHE
AccessioniPrimary (citable) accession number: Q6G1L0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: July 19, 2004
Last modified: September 7, 2016
This is version 70 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.