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Reviewed, UniProtKB/Swiss-Prot Q6G1B5 (AROE_BARQU)

Last modified November 25, 2008. Version 34. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Shikimate dehydrogenase
    EC=1.1.1.25
Gene names
Name: aroE
Ordered Locus Names: BQ00030
OrganismBartonella quintana (Rochalimaea quintana) [Complete proteome] [HAMAP]
Taxonomic identifier803 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Protein attributes

Sequence length293 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is not processed.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Shikimate + NADP(+) = 3-dehydroshikimate + NADPH.

Pathway

Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and PEP: step 4/7.

Sequence similarities

Belongs to the shikimate dehydrogenase family.

Ontologies

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 293293Shikimate dehydrogenase
PRO_0000325104

Regions

Nucleotide binding137 – 1415NADP By similarity

Sites

Active site771Proton acceptor Potential

Sequences

Sequence LengthMass (Da)Tools
Q6G1B5-1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 1802ED4064E6F188

FASTA29332,783
        10         20         30         40         50         60 
MIDLTIKCKE KVPSRAFVVG YPIHHSKSPK IHNFWLKQYG LQGEYLAQEV KLEEFSDFLT 

        70         80         90        100        110        120 
STKKRGFCGG NVTLPYKQEA FRLANYKDEV ATMIGAANTL WYEGDKLCAT NSDAYGFSAN 

       130        140        150        160        170        180 
LDDSAPNWVG ETALIFGAGG AARAILYALK KRGFERICLL NRTRQRADNL AEHFGKPVEV 

       190        200        210        220        230        240 
HDWHNVGEIL YEADLIVNTT SVGMTDPHGW KTGSLFCDFQ KTKTTTLVTD IVYTPLTTPF 

       250        260        270        280        290 
LQQAKAHGLR TVDGLGMLLH QAVPGFERWF GITPQVTKAL RTKILEDMGE ERG 

« Hide

References

[1]"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae."
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Toulouse.

Cross-references

Sequence databases

BX897700 Genomic DNA. Translation: CAF25510.1.
RefSeqYP_031733.1.

3D structure databases

ModBaseSearch...

Genome annotation databases

GeneID2867106.
GenomeReviewsGene locus BQ00030 in contig BX897700_GR.
KEGGbqu:BQ00030.
NMPDRfig|283165.1.peg.3.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMQ6G1B5.

Enzyme and pathway databases

BioCycBQUI283165:BQ00030-MON.

Family and domain databases

HAMAPMF_00222.
[Tree]
InterProIPR016040. NAD(P)-bd.
IPR011342. Quinate/shikimate_5-DHase.
IPR013708. Shikimate_DHase-bd_N.
IPR006151. Shikm_DHase/Glu-tRNA_Rdtase.
[Graphical view]
Gene3DG3DSA:3.40.50.720. NAD(P)-bd. 1 hit.
PfamPF01488. Shikimate_DH. 1 hit.
PF08501. Shikimate_dh_N. 1 hit.
[Graphical view]
TIGRFAMsTIGR00507. aroE. 1 hit.
ProtoNetSearch...

Entry information

Entry nameAROE_BARQU
AccessionPrimary (citable) accession number: Q6G1B5
Entry history
Integrated into UniProtKB/Swiss-Prot: March 18, 2008
Last sequence update: July 19, 2004
Last modified: November 25, 2008
This is version 34 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectHAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)

Relevant documents

PATHWAY comments

Index of metabolic and biosynthesis pathways

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents