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Q6G0T9 (G6PI_BARQU) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Glucose-6-phosphate isomerase

Short name=GPI
EC=5.3.1.9
Alternative name(s):
Phosphoglucose isomerase
Short name=PGI
Phosphohexose isomerase
Short name=PHI
Gene names
Name:pgi
Ordered Locus Names:BQ01300
OrganismBartonella quintana (strain Toulouse) (Rochalimaea quintana) [Complete proteome] [HAMAP]
Taxonomic identifier283165 [NCBI]
Taxonomic lineageBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella

Protein attributes

Sequence length559 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

D-glucose 6-phosphate = D-fructose 6-phosphate. HAMAP-Rule MF_00473

Pathway

Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4. HAMAP-Rule MF_00473

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00473.

Sequence similarities

Belongs to the GPI family.

Ontologies

Keywords
   Biological processGluconeogenesis
Glycolysis
   Cellular componentCytoplasm
   Molecular functionIsomerase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processgluconeogenesis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

glycolysis

Inferred from electronic annotation. Source: UniProtKB-HAMAP

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionglucose-6-phosphate isomerase activity

Inferred from electronic annotation. Source: UniProtKB-HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 559559Glucose-6-phosphate isomerase HAMAP-Rule MF_00473
PRO_0000180599

Sites

Active site3631Proton donor By similarity
Active site3941 By similarity
Active site5231 By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6G0T9 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 3EA4C8DB579305F2

FASTA55962,896
        10         20         30         40         50         60 
MRYKFMGDSL SIRNEKAFEA ALQALRRHAT KDGVYDIRRH FVEDEQRFSH FSLRLDDLLF 

        70         80         90        100        110        120 
DFSKCGITFK TLQLLDDLAV AADVLGRREA MFSGKAINTT EKRSVLHIAL RMPTDEVFML 

       130        140        150        160        170        180 
DGHDLVRDIQ DVLAHMERFS EMVRDGSYKG NTGEKIINIV NIGIGGSDLG PAMVTHALKP 

       190        200        210        220        230        240 
YHDGPHCHFV SNADTAHISD TLSVLNPATT LFIIASKTFT TAETIANAQV ARQWIISHLG 

       250        260        270        280        290        300 
EEAVCRHFVA VSSALDKVAE FGIDSSRIFK FWDWVGGRYS IWSAIGLVVM LAIGGQNFRQ 

       310        320        330        340        350        360 
FLNGAQQMDR HFKIAPLHKN IPIRFALLGF WHRVVCGYAS RAIIPYAQRL ARFPAYLQQL 

       370        380        390        400        410        420 
DMESNGKQVS LDGKTLNFSS GPVVWGDSGT NGQHAFFQLL HQGTDVIPVE FILFIKGHEQ 

       430        440        450        460        470        480 
NLHPMYDILV ANCLAQSKAL MKGRSVEDVR RILVKSGIDV HETEKLALHK SFEGNRPSIM 

       490        500        510        520        530        540 
LVQDLLTPFT LGRLIALYEH RIFVEGILMN INSFDQWGVE FGKELANELL PILRGENKAN 

       550 
NRDSSTLGLL AYIQARREE 

« Hide

References

[1]"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae."
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed] [Europe PMC] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Toulouse.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
BX897700 Genomic DNA. Translation: CAF25635.1.
RefSeqYP_031847.1. NC_005955.1.

3D structure databases

ProteinModelPortalQ6G0T9.
ModBaseSearch...
MobiDBSearch...

Protein-protein interaction databases

STRING283165.BQ01300.

Proteomic databases

PRIDEQ6G0T9.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

EnsemblBacteriaCAF25635; CAF25635; BQ01300.
GeneID2867079.
KEGGbqu:BQ01300.
PATRIC31951419. VBIBarQui58630_0151.

Organism-specific databases

CMRSearch...

Phylogenomic databases

eggNOGCOG0166.
HOGENOMHOG000261371.
KOK01810.
OMALKMHFVS.
OrthoDBEOG64R61J.
ProtClustDBPRK00179.

Enzyme and pathway databases

BioCycBQUI283165:GHZA-130-MONOMER.
UniPathwayUPA00109; UER00181.

Family and domain databases

Gene3D1.10.1390.10. 1 hit.
HAMAPMF_00473. G6P_isomerase.
InterProIPR001672. G6P_Isomerase.
IPR023096. G6P_Isomerase_C.
IPR018189. Phosphoglucose_isomerase_CS.
[Graphical view]
PANTHERPTHR11469. PTHR11469. 1 hit.
PfamPF00342. PGI. 1 hit.
[Graphical view]
PRINTSPR00662. G6PISOMERASE.
PROSITEPS00765. P_GLUCOSE_ISOMERASE_1. 1 hit.
PS00174. P_GLUCOSE_ISOMERASE_2. 1 hit.
PS51463. P_GLUCOSE_ISOMERASE_3. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameG6PI_BARQU
AccessionPrimary (citable) accession number: Q6G0T9
Entry history
Integrated into UniProtKB/Swiss-Prot: March 29, 2005
Last sequence update: July 19, 2004
Last modified: February 19, 2014
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways