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Q6G0R8 (Q6G0R8_BARQU) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 41. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
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Names and origin

Protein namesRecommended name:
Inorganic pyrophosphatase HAMAP MF_00209
EC=3.6.1.1 HAMAP MF_00209
Alternative name(s):
Pyrophosphate phospho-hydrolase HAMAP MF_00209
Gene names
Name:ppa HAMAP MF_00209 EMBL CAF25661.1
Ordered Locus Names:BQ01580
OrganismBartonella quintana (strain Toulouse) (Rochalimaea quintana) [Complete proteome] [HAMAP]
Taxonomic identifier283165 [NCBI]
Taxonomic lineageBacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length176 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

Diphosphate + H2O = 2 phosphate. HAMAP MF_00209

Cofactor

Binds 4 magnesium ions per subunit. Other metal ions can support activity, but at a lower rate. Two magnesium ions are required for the activation of the enzyme and are present before substrate binds, two additional magnesium ions form complexes with substrate and product By similarity. HAMAP MF_00209

Subcellular location

Cytoplasm By similarity HAMAP MF_00209.

Sequence similarities

Belongs to the PPase family. HAMAP MF_00209

Ontologies

Keywords
   Cellular componentCytoplasm HAMAP MF_00209
   LigandMagnesium HAMAP MF_00209
Metal-binding HAMAP MF_00209
   Molecular functionHydrolase HAMAP MF_00209
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processphosphate-containing compound metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioninorganic diphosphatase activity

Inferred from electronic annotation. Source: HAMAP

magnesium ion binding

Inferred from electronic annotation. Source: HAMAP

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Metal binding661Magnesium 1 By similarity HAMAP MF_00209
Metal binding711Magnesium 1 By similarity HAMAP MF_00209
Metal binding711Magnesium 2 By similarity HAMAP MF_00209
Metal binding1031Magnesium 1 By similarity HAMAP MF_00209

Sequences

Sequence LengthMass (Da)Tools
Q6G0R8 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 65921BF3C0337490

FASTA17620,047
        10         20         30         40         50         60 
MNVKEIPVGK NPPEDINVIV EVSLGAQPIK YEMDKKSGAL FVDRFLHTSM VYPGNYGFVP 

        70         80         90        100        110        120 
HTLSDDGDPI DVLICNTRPL IPGCVINVCP IGVLIMEDDG GKDEKIIAIP TPKLTQRYIN 

       130        140        150        160        170 
IYDYTDLPEI TLKQIEHFFK HYKDLEPGKW AKIEGWRDKS FAHQLIKQAI ERNREI

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References

[1]"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae."
Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E.
Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract]
Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
Strain: Toulouse.

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		BX897700 Genomic DNA. Translation: CAF25661.1.
RefSeqYP_031868.1. NC_005955.1.

3D structure databases

ProteinModelPortalQ6G0R8.
SMRQ6G0R8. Positions 3-172.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2866912.
GenomeReviewsGene locus BQ01580 in contig BX897700_GR.
KEGGbqu:BQ01580.
NMPDRfig|283165.1.peg.138.
PATRIC31951481. VBIBarQui58630_0180.

Organism-specific databases

CMRSearch...

Phylogenomic databases

HOGENOMHBG529150.
OMAPNDFNVI.
PhylomeDBQ6G0R8.
ProtClustDBPRK01250.

Family and domain databases

HAMAPMF_00209. Inorganic_PPase.
[Tree]
InterProIPR008162. Pyrophosphatase.
[Graphical view]
Gene3DG3DSA:3.90.80.10. Pyrophosphatase. 1 hit.
KOK01507.
PANTHERPTHR10286. Pyrophosphatase. 1 hit.
PfamPF00719. Pyrophosphatase. 1 hit.
[Graphical view]
SUPFAMSSF50324. Pyrophosphatase. 1 hit.
PROSITEPS00387. PPASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6G0R8_BARQU
AccessionPrimary (citable) accession number: Q6G0R8
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 41 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
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