Reviewed, UniProtKB/Swiss-Prot Q6G070 (PSD_BARQU)

Names and origin

Protein names

Recommended name:
    Phosphatidylserine decarboxylase proenzyme
    EC=4.1.1.65
Cleaved into the following 2 chains:
    1- Recommended name:
            Phosphatidylserine decarboxylase alpha chain
    2- Recommended name:
            Phosphatidylserine decarboxylase beta chain

Gene names

Name:	psd
Synonyms:	psdA
Ordered Locus Names:	BQ04400

Organism

Bartonella quintana (Rochalimaea quintana) [Complete proteome] [HAMAP]

Taxonomic identifier

803 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	233 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is further processed into a mature form.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Phosphatidyl-L-serine = phosphatidylethanolamine + CO2. HAMAP MF_00664
Cofactor	Pyruvoyl group By similarity.
Pathway	Phospholipid metabolism; phosphatidylethanolamine biosynthesis; phosphatidylethanolamine from CDP-diacylglycerol: step 2/2. HAMAP MF_00664
Sequence similarities	Belongs to the phosphatidylserine decarboxylase family. Type 3 subfamily.

Ontologies

Keywords
Biological process	Phospholipid biosynthesis
Ligand	Pyruvate
Molecular function	Decarboxylase Lyase
PTM	Zymogen
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	phosphatidylethanolamine biosynthetic process Inferred from electronic annotation. Source: InterPro
Molecular function	cofactor binding Inferred from electronic annotation. Source: InterPro phosphatidylserine decarboxylase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 189	189	Phosphatidylserine decarboxylase beta chain By similarity		PRO_0000029755
	Chain	190 – 233	44	Phosphatidylserine decarboxylase alpha chain By similarity		PRO_0000029756
Sites
	Site	189 – 190	2	Cleavage (non-hydrolytic) By similarity
Amino acid modifications
	Modified residue	190	1	Pyruvic acid (Ser) By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6G070-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: CE98BBAA66653CCF	FASTA	233	26,179
	10 20 30 40 50 60 MSILQSVHNS FTPVHKEGYP FIIAFFVLSL IFGWVWSPLF WCGLVLTVWC IYFFRDPNRV 70 80 90 100 110 120 IPVNSNWIIS PADGRISFVE PCIPPEELGL GNEEMIRISV FMDIFSCHIN RIPISGKVES 130 140 150 160 170 180 IVYRPGQFAN AELDKASQFN ERNGMVIDSK HGKIGVVQIA GAIARRIVCW SKENDSVITG 190 200 210 220 230 QRFGLIRFGS RLDIYIPTEV KLRVAVGQTA IAGETVLGSF DDKSSATIDF RFD

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Toulouse.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX897700 Genomic DNA. Translation: CAF25939.1.
RefSeq	YP_032120.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2866459.
GenomeReviews	Gene locus BQ04400 in contig BX897700_GR.
KEGG	bqu:BQ04400.
NMPDR	fig|283165.1.peg.390.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6G070.
OMA	IFMSVFN
Enzyme and pathway databases
BioCyc	BQUI283165:BQ04400-MON.
BRENDA	4.1.1.65. 292235.
Family and domain databases
HAMAP	MF_00664. [Tree]
InterPro	IPR003817. PS_Dcarbxylase. IPR004428. PtdSer_deCO2ase_related. [Graphical view]
Pfam	PF02666. PS_Dcarbxylase. 1 hit. [Graphical view]
TIGRFAMs	TIGR00164. PS_decarb_rel. 1 hit.
ProtoNet	Search...

Entry information

Entry name

PSD_BARQU

Accession

Primary (citable) accession number: Q6G070

Entry history

Integrated into UniProtKB/Swiss-Prot:	February 1, 2005
Last sequence update:	July 19, 2004
Last modified:	November 24, 2009
This is version 29 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)