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Q6FZK1

- PUR5_BARQU

UniProt

Q6FZK1 - PUR5_BARQU

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Protein
Phosphoribosylformylglycinamidine cyclo-ligase
Gene
purM, BQ07380
Organism
Bartonella quintana (strain Toulouse) (Rochalimaea quintana)
Status
Reviewed - Annotation score: 2 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + 2-(formamido)-N(1)-(5-phospho-D-ribosyl)acetamidine = ADP + phosphate + 5-amino-1-(5-phospho-D-ribosyl)imidazole.UniRule annotation

Pathwayi

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-KW
  2. phosphoribosylformylglycinamidine cyclo-ligase activity Source: UniProtKB-HAMAP
Complete GO annotation...

GO - Biological processi

  1. 'de novo' IMP biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Ligase

Keywords - Biological processi

Purine biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBQUI283165:GHZA-737-MONOMER.
UniPathwayiUPA00074; UER00129.

Names & Taxonomyi

Protein namesi
Recommended name:
Phosphoribosylformylglycinamidine cyclo-ligase (EC:6.3.3.1)
Alternative name(s):
AIR synthase
AIRS
Phosphoribosyl-aminoimidazole synthetase
Gene namesi
Name:purM
Ordered Locus Names:BQ07380
OrganismiBartonella quintana (strain Toulouse) (Rochalimaea quintana)
Taxonomic identifieri283165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000000597: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 361361Phosphoribosylformylglycinamidine cyclo-ligaseUniRule annotation
PRO_0000258334Add
BLAST

Proteomic databases

PRIDEiQ6FZK1.

Interactioni

Protein-protein interaction databases

STRINGi283165.BQ07380.

Structurei

3D structure databases

ProteinModelPortaliQ6FZK1.
SMRiQ6FZK1. Positions 55-353.

Family & Domainsi

Sequence similaritiesi

Belongs to the AIR synthase family.

Phylogenomic databases

eggNOGiCOG0150.
HOGENOMiHOG000229090.
KOiK01933.
OMAiEFEMYRT.
OrthoDBiEOG61CM1V.

Family and domain databases

Gene3Di3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPiMF_00741_B. AIRS_B.
InterProiIPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view]
PfamiPF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view]
SUPFAMiSSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsiTIGR00878. purM. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FZK1-1 [UniParc]FASTAAdd to Basket

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MSNQDLINCK SNSGLTYAKA GVDIDVGNAM VEKIKPFIRS TKRAGADVEI    50
GGFGGLFDLK AAGFTDPILV AANDGVGTKL KIAIEVGIHD TVGIDLVAMC 100
INDLLVQGAE PLFFLDYFAT GKLDPEQGAA IVSGIAVGCQ QAGAALIGGE 150
TAEMPGMYAK GDYDLAGFAV GATERSALLP SKDLAEGDII LGLSSSGIHS 200
NGFSLVRRIV QQSGLKWGDY APFNPQMNLG TALLTPTRIY VKSLLPIIKT 250
YKGIKALAHI TGGGLPENIP RVLPSSLCAE INLSAIHVPP VFSWIAKQGK 300
IEETEMLRTF NCGIGMVIIV AQHAVETITQ ILEMQGEIVT LLGILTKHPT 350
KKILYKGVLH L 361
Length:361
Mass (Da):38,139
Last modified:July 19, 2004 - v1
Checksum:i2C6FCAB9B2630DF7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX897700 Genomic DNA. Translation: CAF26222.1.
RefSeqiWP_011179474.1. NC_005955.1.
YP_032367.1. NC_005955.1.

Genome annotation databases

EnsemblBacteriaiCAF26222; CAF26222; BQ07380.
GeneIDi2866350.
KEGGibqu:BQ07380.
PATRICi31952777. VBIBarQui58630_0809.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX897700 Genomic DNA. Translation: CAF26222.1 .
RefSeqi WP_011179474.1. NC_005955.1.
YP_032367.1. NC_005955.1.

3D structure databases

ProteinModelPortali Q6FZK1.
SMRi Q6FZK1. Positions 55-353.
ModBasei Search...

Protein-protein interaction databases

STRINGi 283165.BQ07380.

Proteomic databases

PRIDEi Q6FZK1.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF26222 ; CAF26222 ; BQ07380 .
GeneIDi 2866350.
KEGGi bqu:BQ07380.
PATRICi 31952777. VBIBarQui58630_0809.

Phylogenomic databases

eggNOGi COG0150.
HOGENOMi HOG000229090.
KOi K01933.
OMAi EFEMYRT.
OrthoDBi EOG61CM1V.

Enzyme and pathway databases

UniPathwayi UPA00074 ; UER00129 .
BioCyci BQUI283165:GHZA-737-MONOMER.

Family and domain databases

Gene3Di 3.30.1330.10. 1 hit.
3.90.650.10. 1 hit.
HAMAPi MF_00741_B. AIRS_B.
InterProi IPR010918. AIR_synth_C_dom.
IPR000728. AIR_synth_N_dom.
IPR004733. PurM_cligase.
IPR016188. PurM_N-like.
[Graphical view ]
Pfami PF00586. AIRS. 1 hit.
PF02769. AIRS_C. 1 hit.
[Graphical view ]
SUPFAMi SSF55326. SSF55326. 1 hit.
SSF56042. SSF56042. 1 hit.
TIGRFAMsi TIGR00878. purM. 1 hit.
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Toulouse.

Entry informationi

Entry nameiPUR5_BARQU
AccessioniPrimary (citable) accession number: Q6FZK1
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 19, 2004
Last modified: September 3, 2014
This is version 67 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

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