UniProtKB - Q6FZH0 (SYR_BARQU)
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Protein
Arginine--tRNA ligase
Gene
argS
Organism
Bartonella quintana (strain Toulouse) (Rochalimaea quintana)
Status
Functioni
Catalytic activityi
ATP + L-arginine + tRNA(Arg) = AMP + diphosphate + L-arginyl-tRNA(Arg).UniRule annotation
GO - Molecular functioni
- arginine-tRNA ligase activity Source: UniProtKB-EC
- ATP binding Source: UniProtKB-KW
GO - Biological processi
- arginyl-tRNA aminoacylation Source: InterPro
Keywordsi
Molecular function | Aminoacyl-tRNA synthetase, Ligase |
Biological process | Protein biosynthesis |
Ligand | ATP-binding, Nucleotide-binding |
Enzyme and pathway databases
BioCyci | BQUI283165:G1GJ6-782-MONOMER. |
Names & Taxonomyi
Protein namesi | Recommended name: Arginine--tRNA ligaseUniRule annotation (EC:6.1.1.19UniRule annotation)Alternative name(s): Arginyl-tRNA synthetaseUniRule annotation Short name: ArgRSUniRule annotation |
Gene namesi | Name:argSUniRule annotation Ordered Locus Names:BQ07700 |
Organismi | Bartonella quintana (strain Toulouse) (Rochalimaea quintana) |
Taxonomic identifieri | 283165 [NCBI] |
Taxonomic lineagei | Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella › |
Proteomesi |
|
Subcellular locationi
- Cytoplasm UniRule annotation
GO - Cellular componenti
- cytoplasm Source: UniProtKB-SubCell
Keywords - Cellular componenti
CytoplasmPTM / Processingi
Molecule processing
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
ChainiPRO_0000241989 | 1 – 585 | Arginine--tRNA ligaseAdd BLAST | 585 |
Proteomic databases
PRIDEi | Q6FZH0. |
Interactioni
Subunit structurei
Monomer.UniRule annotation
Protein-protein interaction databases
STRINGi | 283165.BQ07700. |
Structurei
3D structure databases
ProteinModelPortali | Q6FZH0. |
SMRi | Q6FZH0. |
ModBasei | Search... |
MobiDBi | Search... |
Family & Domainsi
Motif
Feature key | Position(s) | DescriptionActions | Graphical view | Length |
---|---|---|---|---|
Motifi | 131 – 141 | "HIGH" regionAdd BLAST | 11 |
Sequence similaritiesi
Belongs to the class-I aminoacyl-tRNA synthetase family.UniRule annotation
Phylogenomic databases
eggNOGi | ENOG4105C75. Bacteria. COG0018. LUCA. |
HOGENOMi | HOG000247214. |
KOi | K01887. |
OMAi | NKPLHLG. |
OrthoDBi | POG091H01RF. |
Family and domain databases
CDDi | cd00671. ArgRS_core. 1 hit. |
Gene3Di | 3.30.1360.70. 1 hit. 3.40.50.620. 1 hit. |
HAMAPi | MF_00123. Arg_tRNA_synth. 1 hit. |
InterProi | View protein in InterPro IPR001412. aa-tRNA-synth_I_CS. IPR001278. Arg-tRNA-ligase. IPR005148. Arg-tRNA-synth_N. IPR036695. Arg-tRNA-synth_N_sf. IPR035684. ArgRS_core. IPR008909. DALR_anticod-bd. IPR014729. Rossmann-like_a/b/a_fold. IPR009080. tRNAsynth_Ia_anticodon-bd. |
PANTHERi | PTHR11956. PTHR11956. 1 hit. |
Pfami | View protein in Pfam PF03485. Arg_tRNA_synt_N. 1 hit. PF05746. DALR_1. 1 hit. PF00750. tRNA-synt_1d. 2 hits. |
PRINTSi | PR01038. TRNASYNTHARG. |
SMARTi | View protein in SMART SM01016. Arg_tRNA_synt_N. 1 hit. SM00836. DALR_1. 1 hit. |
SUPFAMi | SSF47323. SSF47323. 1 hit. SSF55190. SSF55190. 1 hit. |
TIGRFAMsi | TIGR00456. argS. 1 hit. |
PROSITEi | View protein in PROSITE PS00178. AA_TRNA_LIGASE_I. 1 hit. |
i Sequence
Sequence statusi: Complete.
Q6FZH0-1 [UniParc]FASTAAdd to basket
10 20 30 40 50
MNVFKNFEKK IKKSLELSDI KGKNGEDLNL SKITVDPPRD SSHGHLSTNA
60 70 80 90 100
AMVLAKSIGL NPHALAEKII ELLKNDSSID CIDIAAPGFI NIKLTKSFWQ
110 120 130 140 150
DAIKSMLKKG TSYGRIPMGQ GKRINVEYVS ANPTGPMHVG HCRGAVFGDV
160 170 180 190 200
LSNLLQFVGY NITKEYYIND AGKQIEVLAH SVLLRYREAL GQKINEIPEG
210 220 230 240 250
LYPGEYLIPL GQSLAQEFSD QLLTIDKDEA LSIVKERAIY AMMSMIRKDL
260 270 280 290 300
AALNIYHDIF FSERMLYADN ARAIRNTIND LTLNGYIYKG ELPPPKGQNT
310 320 330 340 350
EDWEPREQTL FRSTDVGDDQ DRVLVKSDGS YTYFAADVAY FRDKFNRHFD
360 370 380 390 400
EMIYILGADH AGYVKRLEAM AKAISGNSAK LSVFLCQLVK LFRNGHPVRM
410 420 430 440 450
SKRAGSFVTL RDVVEEVGRD PVRFMMLYRK CEAPLDFDFA KVTEQSKDNP
460 470 480 490 500
IFYVQYASAR CHSVFRQAQE IFRIENVSND TMIAHLNRLT DDNEIFLIRK
510 520 530 540 550
LSEYPRIIEQ AVVHKEPHRL AFYLYDLASS FHAHWNKGSD NFDLRFIQPD
560 570 580
DKELSFARLG LIQAIMNILS SGLAIVGIEA ATEMR
Sequence databases
Select the link destinations: EMBLi GenBanki DDBJi Links Updated | BX897700 Genomic DNA. Translation: CAF26254.1. |
RefSeqi | WP_011179505.1. NC_005955.1. |
Genome annotation databases
EnsemblBacteriai | CAF26254; CAF26254; BQ07700. |
GeneIDi | 34145885. |
KEGGi | bqu:BQ07700. |
Similar proteinsi
Entry informationi
Entry namei | SYR_BARQU | |
Accessioni | Q6FZH0Primary (citable) accession number: Q6FZH0 | |
Entry historyi | Integrated into UniProtKB/Swiss-Prot: | June 27, 2006 |
Last sequence update: | July 19, 2004 | |
Last modified: | February 28, 2018 | |
This is version 87 of the entry and version 1 of the sequence. See complete history. | ||
Entry statusi | Reviewed (UniProtKB/Swiss-Prot) | |
Annotation program | Prokaryotic Protein Annotation Program |