Reviewed, UniProtKB/Swiss-Prot Q6FYQ7 (GLMM_BARQU)

Names and origin

Protein names

Recommended name:
    Phosphoglucosamine mutase
    EC=5.4.2.10

Gene names

Name:	glmM
Ordered Locus Names:	BQ11740

Organism

Bartonella quintana (Rochalimaea quintana) [Complete proteome] [HAMAP]

Taxonomic identifier

803 [NCBI]

Taxonomic lineage

Bacteria › Proteobacteria › Alphaproteobacteria › Rhizobiales › Bartonellaceae › Bartonella

Protein attributes

Sequence length	459 AA.
Sequence status	Complete.
Sequence processing	The displayed sequence is not processed.
Protein existence	Inferred from homology.

General annotation (Comments)

Function	Catalyzes the conversion of glucosamine-6-phosphate to glucosamine-1-phosphate By similarity.
Catalytic activity	Alpha-D-glucosamine 1-phosphate = D-glucosamine 6-phosphate. HAMAP MF_01554
Cofactor	Binds 1 magnesium ion per subunit By similarity.
Post-translational modification	Activated by phosphorylation By similarity.
Sequence similarities	Belongs to the phosphohexose mutase family.

Ontologies

Keywords
Ligand	Magnesium Metal-binding
Molecular function	Isomerase
PTM	Phosphoprotein
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	carbohydrate metabolic process Inferred from electronic annotation. Source: InterPro
Molecular function	magnesium ion binding Inferred from electronic annotation. Source: UniProtKB-KW phosphoglucosamine mutase activity Inferred from electronic annotation. Source: HAMAP
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 459	459	Phosphoglucosamine mutase HAMAP MF_01554		PRO_0000147849
Sites
	Active site	102	1	Phosphoserine intermediate By similarity
	Metal binding	102	1	Magnesium; via phosphate group By similarity
	Metal binding	243	1	Magnesium By similarity
	Metal binding	245	1	Magnesium By similarity
	Metal binding	247	1	Magnesium By similarity
Amino acid modifications
	Modified residue	102	1	Phosphoserine By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6FYQ7-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: F2D519773F534588	FASTA	459	49,802
	10 20 30 40 50 60 MAQKYFGTDG IRGKANVFPM TPDFAMKVGM AVGVLFRSQR QSRRVVIGKD TRLSGYMLEN 70 80 90 100 110 120 ALVSGFTAAG MEAFLLGPVP TPAVAMLCRS LRADLGVMIS ASHNPFYDNG IKLFGPDGFK 130 140 150 160 170 180 LSDEIEKKIE QLIDTDLSKS LASCAEIGYA KRVEGDIYRY IEYAKRTLPR DVRLDALRIV 190 200 210 220 230 240 VDCANGAAYK AAPRALWELG AEVFAINDAP NGTNINQKCG STDLASLKQK VHEVRADVGI 250 260 270 280 290 300 ALDGDGDRVL IVDEKAQTVD GDQLIAVIAE HWHKTGRLQG NGVVTTIMSN LGLERFLNRK 310 320 330 340 350 360 GLELVRTNVG DRYVVDAMRQ KGYNIGGEAS GHIVLSDFGT TGDGLVAALQ ILACMQESQS 370 380 390 400 410 420 SMSHLCKRFE PVPQILKNVT IKNKNVLKKN QVKTAIDQAT QRLGNEARLV IRASGTEPVI 430 440 450 RIMGEGDERE VLDAVVAEMV DVIAHHDALS KVGASLEGS

References

[1]

"The louse-borne human pathogen Bartonella quintana is a genomic derivative of the zoonotic agent Bartonella henselae." Alsmark U.C.M., Frank A.C., Karlberg E.O., Legault B.-A., Ardell D.H., Canbaeck B., Eriksson A.-S., Naeslund A.K., Handley S.A., Huvet M., La Scola B., Holmberg M., Andersson S.G.E. Proc. Natl. Acad. Sci. U.S.A. 101:9716-9721(2004) [PubMed: 15210978] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: Toulouse.

Cross-references

Sequence databases
EMBLGenBankDDBJ	BX897700 Genomic DNA. Translation: CAF26633.1.
RefSeq	YP_032707.1.
3D structure databases
ModBase	Search...
Genome annotation databases
GeneID	2866668.
GenomeReviews	Gene locus BQ11740 in contig BX897700_GR.
KEGG	bqu:BQ11740.
NMPDR	fig|283165.1.peg.977.
Organism-specific databases
CMR	Search...
Phylogenomic databases
HOGENOM	Q6FYQ7.
OMA	VHDRYIE.
Enzyme and pathway databases
BioCyc	BQUI283165:BQ11740-MON.
BRENDA	5.4.2.10. 292235.
Family and domain databases
HAMAP	MF_01554. [Tree]
InterPro	IPR005844. A-D-PHexomutase_a/b/a-I. IPR016055. A-D-PHexomutase_a/b/a-I/II/III. IPR005845. A-D-PHexomutase_a/b/a-II. IPR005846. A-D-PHexomutase_a/b/a-III. IPR005843. A-D-PHexomutase_C. IPR016066. A-D-PHexomutase_CS. IPR005841. A-D-PHexomutase_N. IPR006352. GlmM. [Graphical view]
Gene3D	G3DSA:3.40.120.10. A-D-PHexomutase_a/b/a-I/II/III. 3 hits.
Pfam	PF02878. PGM_PMM_I. 1 hit. PF02879. PGM_PMM_II. 1 hit. PF02880. PGM_PMM_III. 1 hit. PF00408. PGM_PMM_IV. 1 hit. [Graphical view]
PRINTS	PR00509. PGMPMM.
TIGRFAMs	TIGR01455. glmM. 1 hit.
PROSITE	PS00710. PGM_PMM. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLMM_BARQU

Accession

Primary (citable) accession number: Q6FYQ7

Entry history

Integrated into UniProtKB/Swiss-Prot:	December 20, 2005
Last sequence update:	July 19, 2004
Last modified:	November 3, 2009
This is version 35 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

HAMAP (High-quality Automated and Manual Annotation of microbial Proteomes)