SubmitCancel

Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6FYL6

- SYL_BARQU

UniProt

Q6FYL6 - SYL_BARQU

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein
Leucine--tRNA ligase
Gene
leuS, BQ12310
Organism
Bartonella quintana (strain Toulouse) (Rochalimaea quintana)
Status
Reviewed - Annotation score: 3 out of 5 - Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-leucine + tRNA(Leu) = AMP + diphosphate + L-leucyl-tRNA(Leu).UniRule annotation

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Binding sitei641 – 6411ATP By similarity

GO - Molecular functioni

  1. ATP binding Source: UniProtKB-HAMAP
  2. aminoacyl-tRNA editing activity Source: InterPro
  3. leucine-tRNA ligase activity Source: UniProtKB-HAMAP

GO - Biological processi

  1. leucyl-tRNA aminoacylation Source: UniProtKB-HAMAP
Complete GO annotation...

Keywords - Molecular functioni

Aminoacyl-tRNA synthetase, Ligase

Keywords - Biological processi

Protein biosynthesis

Keywords - Ligandi

ATP-binding, Nucleotide-binding

Enzyme and pathway databases

BioCyciBQUI283165:GHZA-1229-MONOMER.

Names & Taxonomyi

Protein namesi
Recommended name:
Leucine--tRNA ligase (EC:6.1.1.4)
Alternative name(s):
Leucyl-tRNA synthetase
Short name:
LeuRS
Gene namesi
Name:leuS
Ordered Locus Names:BQ12310
OrganismiBartonella quintana (strain Toulouse) (Rochalimaea quintana)
Taxonomic identifieri283165 [NCBI]
Taxonomic lineageiBacteriaProteobacteriaAlphaproteobacteriaRhizobialesBartonellaceaeBartonella
ProteomesiUP000000597: Chromosome

Subcellular locationi

Cytoplasm By similarity UniRule annotation

GO - Cellular componenti

  1. cytoplasm Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 880880Leucine--tRNA ligaseUniRule annotation
PRO_0000151976Add
BLAST

Proteomic databases

PRIDEiQ6FYL6.

Interactioni

Protein-protein interaction databases

STRINGi283165.BQ12310.

Structurei

3D structure databases

ProteinModelPortaliQ6FYL6.

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi49 – 5911"HIGH" regionUniRule annotation
Add
BLAST
Motifi638 – 6425"KMSKS" regionUniRule annotation

Sequence similaritiesi

Phylogenomic databases

eggNOGiCOG0495.
HOGENOMiHOG000200747.
KOiK01869.
OMAiHISHELW.
OrthoDBiEOG63Z74X.

Family and domain databases

Gene3Di1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPiMF_00049_B. Leu_tRNA_synth_B.
InterProiIPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view]
PANTHERiPTHR11946:SF7. PTHR11946:SF7. 1 hit.
PfamiPF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view]
PRINTSiPR00985. TRNASYNTHLEU.
SUPFAMiSSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsiTIGR00396. leuS_bact. 1 hit.
PROSITEiPS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FYL6-1 [UniParc]FASTAAdd to Basket

« Hide

MTIEHSNVGE RYNPRAREQK WQAIWDEKKI FQITEENCRE KYYVLEMFPY    50
PSGRIHMGHV RNYTMGDVVA RYKRAKGFDV LHPMGWDAFG MPAENAALQS 100
KVHPKTWTYQ NIAVMRGQLK QLGLSLDWSR EFATCDVAYY HRQQMLFLDL 150
YQKGLVARKV AKVNWDPVDQ TVLANEQVVD GCGWRSGALV EQRELAQWFF 200
KISDFSEDLL AGLEELEQWP EKVRTMQKNW IGKSQGLLIR WALKSTNGAD 250
EVCEAFNEVV CYSTRPDTLF GASFLALSVD HPISQALAQK DKALSAFIEN 300
CRCGGMTTAA LETAEKQGFC TSLLAVHPFN PRIHLPVYIA NFVLMDYGTG 350
AVFGCPAHDQ RDWDFAHKYD LPVQPVVLPK GSDAEDFVIA ETPYTGDGVM 400
INSDFLDGLT PQEAFEAAAE RLEGQMLNGQ PQGKRTVQFR LRDWGISRQR 450
YWGCPIPIIH CAACGVVPVP RADLPVELPD DVTFDQPGNP LERHEKWQKV 500
ACPVCGQSAK RETDTMDTFV DSSWYYARFT APWAQEPVDK NAIAEWLPVQ 550
QYIGGIEHAI LHLLYARFFM RAMKLIGYVT VDEPFKGLFT QGMVVHETYR 600
DDQGWVSPAE ISIIEKDGKR QAHKLTDQSE VTIGLIEKMS KSKKNVVDPD 650
DIIASYGADT VRWFVLSDSP PERDVIWTES GVEGAYRFVQ RVWRCVVLSA 700
PVLKEVIPCT GHQGAALELS KAAHRMLCTV EDDLEKFAFN RAIARLYEFL 750
NIMAPLLNKI ASVEDEMKAS LRQAMDFFLA LIAPIMPHLA EECHAALGGK 800
TLICELPWPV YDPALIVEDC CTLPVQINGK KRGEVTVAAT ASEAMIEEAV 850
LALDFVQAHL VEKSIKKMII VPQRIVNVVL 880
Length:880
Mass (Da):99,339
Last modified:July 19, 2004 - v1
Checksum:i135ECA8B81E0C70E
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX897700 Genomic DNA. Translation: CAF26690.1.
RefSeqiWP_011179859.1. NC_005955.1.
YP_032759.1. NC_005955.1.

Genome annotation databases

EnsemblBacteriaiCAF26690; CAF26690; BQ12310.
GeneIDi2867619.
KEGGibqu:BQ12310.
PATRICi31953895. VBIBarQui58630_1345.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
BX897700 Genomic DNA. Translation: CAF26690.1 .
RefSeqi WP_011179859.1. NC_005955.1.
YP_032759.1. NC_005955.1.

3D structure databases

ProteinModelPortali Q6FYL6.
ModBasei Search...
MobiDBi Search...

Protein-protein interaction databases

STRINGi 283165.BQ12310.

Proteomic databases

PRIDEi Q6FYL6.

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

EnsemblBacteriai CAF26690 ; CAF26690 ; BQ12310 .
GeneIDi 2867619.
KEGGi bqu:BQ12310.
PATRICi 31953895. VBIBarQui58630_1345.

Phylogenomic databases

eggNOGi COG0495.
HOGENOMi HOG000200747.
KOi K01869.
OMAi HISHELW.
OrthoDBi EOG63Z74X.

Enzyme and pathway databases

BioCyci BQUI283165:GHZA-1229-MONOMER.

Family and domain databases

Gene3Di 1.10.730.10. 1 hit.
3.40.50.620. 3 hits.
3.90.740.10. 1 hit.
HAMAPi MF_00049_B. Leu_tRNA_synth_B.
InterProi IPR001412. aa-tRNA-synth_I_CS.
IPR002300. aa-tRNA-synth_Ia.
IPR002302. Leu-tRNA-ligase.
IPR025709. Leu_tRNA-synth_edit.
IPR014729. Rossmann-like_a/b/a_fold.
IPR009080. tRNAsynth_1a_anticodon-bd.
IPR013155. V/L/I-tRNA-synth_anticodon-bd.
IPR009008. Val/Leu/Ile-tRNA-synth_edit.
[Graphical view ]
PANTHERi PTHR11946:SF7. PTHR11946:SF7. 1 hit.
Pfami PF08264. Anticodon_1. 1 hit.
PF00133. tRNA-synt_1. 3 hits.
PF13603. tRNA-synt_1_2. 1 hit.
[Graphical view ]
PRINTSi PR00985. TRNASYNTHLEU.
SUPFAMi SSF47323. SSF47323. 1 hit.
SSF50677. SSF50677. 1 hit.
TIGRFAMsi TIGR00396. leuS_bact. 1 hit.
PROSITEi PS00178. AA_TRNA_LIGASE_I. 1 hit.
[Graphical view ]
ProtoNeti Search...

Publicationsi

  1. Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: Toulouse.

Entry informationi

Entry nameiSYL_BARQU
AccessioniPrimary (citable) accession number: Q6FYL6
Entry historyi
Integrated into UniProtKB/Swiss-Prot: March 1, 2005
Last sequence update: July 19, 2004
Last modified: September 3, 2014
This is version 71 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programProkaryotic Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome

Documents

  1. Aminoacyl-tRNA synthetases
    List of aminoacyl-tRNA synthetase entries
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi