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Protein

Hexokinase

Gene

CAGL0A04829g

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Ordered Locus Names:CAGL0A04829gImported
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428 Componenti: Chromosome A

Organism-specific databases

EuPathDBiFungiDB:CAGL0A04829g.

Structurei

3D structure databases

ProteinModelPortaliQ6FXT8.
SMRiQ6FXT8. Positions 18-486.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ6FXT8.
KOiK00844.
OMAiEELWSFI.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FXT8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MVHLGPKKPP TRKGSMVDMP QQLLDQIKVF EEMYTVDGET LRKVTKHFIT
60 70 80 90 100
ELDKGLSKKG GNIPMIPGWV MEYPSGKEKG DYLAIDLGGT NLRVVLVKLG
110 120 130 140 150
GDRTFDTTQS KYKLPEAMRT TKNHEELWSF IADSLQAFLE DQFPEGVKGK
160 170 180 190 200
LPLGFTFSYP ASQDRINQGV LQRWTKGFDI PNVEGHDVVP MLQKQIEKRN
210 220 230 240 250
LPIDIVALIN DTTGTLVASL YTDGETKMGV IFGTGVNGAY YDVVSDIPKL
260 270 280 290 300
EGKLADDIPN DSPMAINCEY GSFDNEHVVL PRNKYDLIID EESPRPGQQA
310 320 330 340 350
FEKMSSGYYL GEMLRLALLD LYDQGLILKG QDISKLKKPY VMDTSYPSKI
360 370 380 390 400
EDDPFENLED TDELLQKNLG IQTTVQERKL IRRLCELIGT RSARLSVCGI
410 420 430 440 450
AAICQKRGYE TAHIAADGSV FKMYPGFKEK AAQGLADIYG WEHKDPKDCP
460 470 480
IVIVDAEDGS GAGAAIIAAL AEKRIAEGKS LGVLGA
Length:486
Mass (Da):53,806
Last modified:July 19, 2004 - v1
Checksum:i775B3314FE65B2A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380947 Genomic DNA. Translation: CAG57871.1.
RefSeqiXP_444978.1. XM_444978.1.

Genome annotation databases

GeneIDi2886356.
KEGGicgr:CAGL0A04829g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380947 Genomic DNA. Translation: CAG57871.1.
RefSeqiXP_444978.1. XM_444978.1.

3D structure databases

ProteinModelPortaliQ6FXT8.
SMRiQ6FXT8. Positions 18-486.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2886356.
KEGGicgr:CAGL0A04829g.

Organism-specific databases

EuPathDBiFungiDB:CAGL0A04829g.

Phylogenomic databases

HOGENOMiHOG000162670.
InParanoidiQ6FXT8.
KOiK00844.
OMAiEELWSFI.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR022673. Hexokinase_C.
IPR019807. Hexokinase_CS.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PRINTSiPR00475. HEXOKINASE.
PROSITEiPS00378. HEXOKINASES. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome evolution in yeasts."
    Genolevures
    Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
    , Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L., Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.L.
    Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65Imported.

Entry informationi

Entry nameiQ6FXT8_CANGA
AccessioniPrimary (citable) accession number: Q6FXT8
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: May 27, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.