Skip Header

Contribute Send feedback
Read comments (?) or add your own

Q6FWX3 (Q6FWX3_CANGA) Unreviewed, UniProtKB/TrEMBL

Last modified January 25, 2012. Version 59. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry infoCustomize order

Names and origin

Protein namesRecommended name:
Adenosylhomocysteinase RuleBase RU000548
EC=3.3.1.1 RuleBase RU000548
Gene names
Ordered Locus Names:CAGL0C02189g
OrganismCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) [Complete proteome]
Taxonomic identifier284593 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Nakaseomyces › mitosporic Nakaseomyces

Protein attributes

Sequence length449 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

S-adenosyl-L-homocysteine + H2O = L-homocysteine + adenosine. RuleBase RU000548

Cofactor

NAD By similarity. RuleBase RU000548

Pathway

Amino-acid biosynthesis; homocysteine biosynthesis; L-homocysteine from S-adenosyl-L-homocysteine: step 1/1. RuleBase RU000548

Sequence similarities

Belongs to the adenosylhomocysteinase family. RuleBase RU004166

Ontologies

Keywords
   Biological processOne-carbon metabolism RuleBase RU000548
   LigandNAD RuleBase RU000548
   Molecular functionHydrolase RuleBase RU000548
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processone-carbon metabolic process

Inferred from electronic annotation. Source: UniProtKB-KW

   Molecular functionadenosylhomocysteinase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Sites

Binding site581Substrate By similarity PIRSR PIRSR001109-1
Binding site1341Substrate By similarity PIRSR PIRSR001109-1
Binding site1591Substrate By similarity PIRSR PIRSR001109-1
Binding site1891Substrate By similarity PIRSR PIRSR001109-1
Binding site1931Substrate By similarity PIRSR PIRSR001109-1

Sequences

Sequence LengthMass (Da)Tools
Q6FWX3 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 8C93D8B0B0888E26

FASTA44949,192
        10         20         30         40         50         60 
MSAPAQNYKI ADISLAAFGR KEIELAENEM PGLMAIRKAY AEAQPLKGAR IAGCLHMTIQ 

        70         80         90        100        110        120 
TAVLIETLVA LGAEVTWTSC NIYSTQDHAA AAIAASGVPV FAWKGETEEE YMWCIEQQLF 

       130        140        150        160        170        180 
AFKDNKKLNL ILDDGGDLTS FVHEKYPEML TDCFGLSEET TTGVHHLYRM MREGKLKVPA 

       190        200        210        220        230        240 
INVNDAVTKS KFDNLYGCRE SLVDGIKRAT DVMLAGKVAV VAGFGDVGKG CAASLRGMGA 

       250        260        270        280        290        300 
RVLVTEIDPI NALQAAMEGY EVTTMEDAAS VGQVFVTTTG CRDIIKGEHF EKMPEDAIVC 

       310        320        330        340        350        360 
NIGHFDIEID VAWLKENAKE CINIKPQVDR YLLSSGRHVI LLANGRLVNL GCATGHSSFV 

       370        380        390        400        410        420 
MSCSFSNQVL AQIALFKSDD KAFRTKFVEF EKTGPFEVGV HVLPKILDEA VAKFHLEKLG 

       430        440 
VKLTTLSDVQ SEYLGIPQQG PFKADHYRY

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR380949 Genomic DNA. Translation: CAG58177.1.
RefSeqXP_445271.1. XM_445271.1.

3D structure databases

ProteinModelPortalQ6FWX3.
SMRQ6FWX3. Positions 8-449.
ModBaseSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2886930.
GenomeReviewsGene locus CAGL0C02189g in contig CR380949_GR.
KEGGcgr:CAGL0C02189g.

Phylogenomic databases

eggNOGfuNOG06806.
HOGENOMHBG352029.
OMASAQVWVT.
OrthoDBEOG41G6CK.

Family and domain databases

HAMAPMF_00563. AdoHcyase.
[Tree]
InterProIPR000043. Adenosylhomocysteinase.
IPR015878. Ado_hCys_hydrolase_NAD-bd.
IPR020082. S-Ado-L-homoCys_hydrolase_CS.
[Graphical view]
KOK01251.
PANTHERPTHR23420. Ad_hcy_hydrolase. 1 hit.
PfamPF05221. AdoHcyase. 1 hit.
PF00670. AdoHcyase_NAD. 1 hit.
[Graphical view]
PIRSFPIRSF001109. Ad_hcy_hydrolase. 1 hit.
SMARTSM00996. AdoHcyase. 1 hit.
SM00997. AdoHcyase_NAD. 1 hit.
[Graphical view]
TIGRFAMsTIGR00936. AhcY. 1 hit.
PROSITEPS00738. ADOHCYASE_1. 1 hit.
PS00739. ADOHCYASE_2. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameQ6FWX3_CANGA
AccessionPrimary (citable) accession number: Q6FWX3
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: January 25, 2012
This is version 59 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info