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Protein

Hexokinase

Gene

GLK1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + D-hexose = ADP + D-hexose 6-phosphate.UniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

KinaseUniRule annotationSAAS annotation, Transferase

Keywords - Biological processi

GlycolysisUniRule annotationSAAS annotation

Keywords - Ligandi

ATP-bindingUniRule annotationSAAS annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
HexokinaseUniRule annotation (EC:2.7.1.1UniRule annotation)
Gene namesi
Name:GLK1Imported
Ordered Locus Names:CAGL0F00605gImported
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
Proteomesi
  • UP000002428 Componenti: Chromosome F

Organism-specific databases

CGDiCAL0131300. GLK1.
EuPathDBiFungiDB:CAGL0F00605g.

Subcellular locationi

GO - Cellular componenti

  • cytosol Source: CGD
Complete GO annotation...

Interactioni

Protein-protein interaction databases

STRINGi284593.XP_446000.1.

Structurei

3D structure databases

ProteinModelPortaliQ6FUU4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini17 – 224208Hexokinase_1InterPro annotationAdd
BLAST
Domaini241 – 494254Hexokinase_2InterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the hexokinase family.UniRule annotation

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
HOGENOMiHOG000162670.
InParanoidiQ6FUU4.
KOiK00844.
OMAiGEVEIGC.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FUU4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSFENFHKAT SEQLTKAVDE LCKEFEVTPK MLDELTAYFI ESMEKGLAAE
60 70 80 90 100
ADSENKGLPM IPSFVTGMPN GTENGVLLAA DLGGTNFRVC SVTLNGDNTF
110 120 130 140 150
KMEQMKSKIP DELLDDEGVT SEQLFGYLGR RTVAFVKKYH PEFLNKGDDI
160 170 180 190 200
PPIRLGFTFS YPVDQTSLNS GTLIRWTKGF KIEDTVGKDV VQLYQQQLDA
210 220 230 240 250
QGLGMIKIVA MTNDTVGTFL SHCYASGSHS SSGGEISEPV IGCIFGTGTN
260 270 280 290 300
GCYMEEIENI KKLPEDMRHQ LANEGKTHMC VNTEWGSFDN ECRYLPTTKY
310 320 330 340 350
DVDIDQKYSA NPGFHLFEKR VSGMYLGEVL RNVLVDLHSR GLMLTQYRDY
360 370 380 390 400
DQLPHRLKTP FELSSEVLSR IEIDDSTGLR ETELSFLQSL RLPTTPSERE
410 420 430 440 450
AIQKLVRAIS RRSAYLASVP IAAILIKTNA LNKRYHGEVE VGCDGSVIEY
460 470 480 490
YPGFRSMLRH ALSLSPIGAD GERKIHIRIA KDGSGVGAAL CALVA
Length:495
Mass (Da):54,955
Last modified:July 19, 2004 - v1
Checksum:iA5D022CEE6224AA7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380952 Genomic DNA. Translation: CAG58924.1.
RefSeqiXP_446000.1. XM_446000.1.

Genome annotation databases

EnsemblFungiiCAG58924; CAG58924; CAGL0F00605g.
GeneIDi2887872.
KEGGicgr:CAGL0F00605g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380952 Genomic DNA. Translation: CAG58924.1.
RefSeqiXP_446000.1. XM_446000.1.

3D structure databases

ProteinModelPortaliQ6FUU4.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi284593.XP_446000.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

EnsemblFungiiCAG58924; CAG58924; CAGL0F00605g.
GeneIDi2887872.
KEGGicgr:CAGL0F00605g.

Organism-specific databases

CGDiCAL0131300. GLK1.
EuPathDBiFungiDB:CAGL0F00605g.

Phylogenomic databases

eggNOGiKOG1369. Eukaryota.
COG5026. LUCA.
HOGENOMiHOG000162670.
InParanoidiQ6FUU4.
KOiK00844.
OMAiGEVEIGC.
OrthoDBiEOG79SF68.

Family and domain databases

InterProiIPR001312. Hexokinase.
IPR019807. Hexokinase_BS.
IPR022673. Hexokinase_C.
IPR022672. Hexokinase_N.
[Graphical view]
PANTHERiPTHR19443. PTHR19443. 1 hit.
PfamiPF00349. Hexokinase_1. 1 hit.
PF03727. Hexokinase_2. 1 hit.
[Graphical view]
PROSITEiPS00378. HEXOKINASE_1. 1 hit.
PS51748. HEXOKINASE_2. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Genome evolution in yeasts."
    Genolevures
    Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
    , Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L., Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.L.
    Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65Imported.

Entry informationi

Entry nameiQ6FUU4_CANGA
AccessioniPrimary (citable) accession number: Q6FUU4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: March 16, 2016
This is version 76 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.