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Q6FUS3

- SIL1_CANGA

UniProt

Q6FUS3 - SIL1_CANGA

Protein

Nucleotide exchange factor SIL1

Gene

SIL1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi
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    • History
      Entry version 52 (01 Oct 2014)
      Sequence version 1 (19 Jul 2004)
      Previous versions | rss
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    Functioni

    Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 By similarity.By similarity

    GO - Biological processi

    1. protein transport Source: UniProtKB-KW

    Keywords - Biological processi

    Protein transport, Translocation, Transport

    Names & Taxonomyi

    Protein namesi
    Recommended name:
    Nucleotide exchange factor SIL1
    Gene namesi
    Name:SIL1
    Ordered Locus Names:CAGL0F01089g
    OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
    Taxonomic identifieri284593 [NCBI]
    Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesmitosporic Nakaseomyces
    ProteomesiUP000002428: Chromosome F

    Subcellular locationi

    GO - Cellular componenti

    1. endoplasmic reticulum lumen Source: UniProtKB-SubCell

    Keywords - Cellular componenti

    Endoplasmic reticulum

    PTM / Processingi

    Molecule processing

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Signal peptidei1 – 2121Sequence AnalysisAdd
    BLAST
    Chaini22 – 339318Nucleotide exchange factor SIL1PRO_0000223361Add
    BLAST

    Interactioni

    Subunit structurei

    Interacts with KAR2.By similarity

    Family & Domainsi

    Motif

    Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
    Motifi336 – 3394Prevents secretion from ERSequence Analysis

    Sequence similaritiesi

    Belongs to the SIL1 family.Curated

    Keywords - Domaini

    Signal

    Phylogenomic databases

    KOiK14001.
    OrthoDBiEOG7V1G2Q.

    Sequencei

    Sequence statusi: Complete.

    Sequence processingi: The displayed sequence is further processed into a mature form.

    Q6FUS3-1 [UniParc]FASTAAdd to Basket

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    MVAKVWSRVI LIFIATVMVF ASSQQGDANK VNTASPPGAN GIAYASVVAG    50
    GSNHVSAAGS VTGDGVQLPN AEVDIDWLEE HLEDSHDYEK GYDLVEQHFN 100
    KLLVGNNADA SFKVRELASR LILGTLRNNP PVKRLIWDQH PLFVSQVFDL 150
    YIGNALKQGS GNPLKYPLLK RYLSILLELI PFNRDFRFEE DYKDILDKLY 200
    TESDVPSDIK IKVLELITLD YSNIKGASGW IDRITNVLTD SEMGLDELHK 250
    RTFFNAMHAL KSEDPKLKLP TNFLNWLAQE TKERAHNLKL AQAQADDNDL 300
    KVRDLEQEEF DQRLVDSRHS VFGNPMAARM KDPYIVDEL 339
    Length:339
    Mass (Da):38,225
    Last modified:July 19, 2004 - v1
    Checksum:i45FB1C2135123780
    GO

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR380952 Genomic DNA. Translation: CAG58945.1.
    RefSeqiXP_446021.1. XM_446021.1.

    Genome annotation databases

    GeneIDi2887649.
    KEGGicgr:CAGL0F01089g.

    Cross-referencesi

    Sequence databases

    Select the link destinations:
    EMBL
    GenBank
    DDBJ
    Links Updated
    CR380952 Genomic DNA. Translation: CAG58945.1 .
    RefSeqi XP_446021.1. XM_446021.1.

    3D structure databases

    ModBasei Search...
    MobiDBi Search...

    Protocols and materials databases

    Structural Biology Knowledgebase Search...

    Genome annotation databases

    GeneIDi 2887649.
    KEGGi cgr:CAGL0F01089g.

    Phylogenomic databases

    KOi K14001.
    OrthoDBi EOG7V1G2Q.

    Family and domain databases

    ProtoNeti Search...

    Entry informationi

    Entry nameiSIL1_CANGA
    AccessioniPrimary (citable) accession number: Q6FUS3
    Entry historyi
    Integrated into UniProtKB/Swiss-Prot: February 21, 2006
    Last sequence update: July 19, 2004
    Last modified: October 1, 2014
    This is version 52 of the entry and version 1 of the sequence. [Complete history]
    Entry statusiReviewed (UniProtKB/Swiss-Prot)
    Annotation programFungal Protein Annotation Program

    Miscellaneousi

    Keywords - Technical termi

    Complete proteome, Reference proteome

    Documents

    1. SIMILARITY comments
      Index of protein domains and families

    External Data

    Dasty 3