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Q6FUS3 (SIL1_CANGA) Reviewed, UniProtKB/Swiss-Prot

Last modified May 14, 2014. Version 51. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Nucleotide exchange factor SIL1
Gene names
Name:SIL1
Ordered Locus Names:CAGL0F01089g
OrganismCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) [Complete proteome]
Taxonomic identifier284593 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesmitosporic Nakaseomyces

Protein attributes

Sequence length339 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology

General annotation (Comments)

Function

Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 By similarity.

Subunit structure

Interacts with KAR2 By similarity.

Subcellular location

Endoplasmic reticulum lumen By similarity.

Sequence similarities

Belongs to the SIL1 family.

Ontologies

Keywords
   Biological processProtein transport
Translocation
Transport
   Cellular componentEndoplasmic reticulum
   DomainSignal
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processprotein transport

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular_componentendoplasmic reticulum lumen

Inferred from electronic annotation. Source: UniProtKB-SubCell

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Signal peptide1 – 2121 Potential
Chain22 – 339318Nucleotide exchange factor SIL1
PRO_0000223361

Regions

Motif336 – 3394Prevents secretion from ER Potential

Sequences

Sequence LengthMass (Da)Tools
Q6FUS3 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 45FB1C2135123780

FASTA33938,225
        10         20         30         40         50         60 
MVAKVWSRVI LIFIATVMVF ASSQQGDANK VNTASPPGAN GIAYASVVAG GSNHVSAAGS 

        70         80         90        100        110        120 
VTGDGVQLPN AEVDIDWLEE HLEDSHDYEK GYDLVEQHFN KLLVGNNADA SFKVRELASR 

       130        140        150        160        170        180 
LILGTLRNNP PVKRLIWDQH PLFVSQVFDL YIGNALKQGS GNPLKYPLLK RYLSILLELI 

       190        200        210        220        230        240 
PFNRDFRFEE DYKDILDKLY TESDVPSDIK IKVLELITLD YSNIKGASGW IDRITNVLTD 

       250        260        270        280        290        300 
SEMGLDELHK RTFFNAMHAL KSEDPKLKLP TNFLNWLAQE TKERAHNLKL AQAQADDNDL 

       310        320        330 
KVRDLEQEEF DQRLVDSRHS VFGNPMAARM KDPYIVDEL 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR380952 Genomic DNA. Translation: CAG58945.1.
RefSeqXP_446021.1. XM_446021.1.

3D structure databases

ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2887649.
KEGGcgr:CAGL0F01089g.

Phylogenomic databases

KOK14001.
OrthoDBEOG7V1G2Q.

Family and domain databases

ProtoNetSearch...

Entry information

Entry nameSIL1_CANGA
AccessionPrimary (citable) accession number: Q6FUS3
Entry history
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 19, 2004
Last modified: May 14, 2014
This is version 51 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families