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Q6FUS3

- SIL1_CANGA

UniProt

Q6FUS3 - SIL1_CANGA

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Protein

Nucleotide exchange factor SIL1

Gene

SIL1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Required for protein translocation and folding in the endoplasmic reticulum (ER). Functions as a nucleotide exchange factor for the ER lumenal chaperone KAR2 (By similarity).By similarity

GO - Biological processi

  1. protein transport Source: UniProtKB-KW
Complete GO annotation...

Keywords - Biological processi

Protein transport, Translocation, Transport

Names & Taxonomyi

Protein namesi
Recommended name:
Nucleotide exchange factor SIL1
Gene namesi
Name:SIL1
Ordered Locus Names:CAGL0F01089g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428: Chromosome F

Subcellular locationi

GO - Cellular componenti

  1. endoplasmic reticulum Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Endoplasmic reticulum

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2121Sequence AnalysisAdd
BLAST
Chaini22 – 339318Nucleotide exchange factor SIL1PRO_0000223361Add
BLAST

Interactioni

Subunit structurei

Interacts with KAR2.By similarity

Family & Domainsi

Motif

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Motifi336 – 3394Prevents secretion from ERSequence Analysis

Sequence similaritiesi

Belongs to the SIL1 family.Curated

Keywords - Domaini

Signal

Phylogenomic databases

InParanoidiQ6FUS3.
KOiK14001.
OrthoDBiEOG7V1G2Q.

Sequencei

Sequence statusi: Complete.

Sequence processingi: The displayed sequence is further processed into a mature form.

Q6FUS3-1 [UniParc]FASTAAdd to Basket

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        10         20         30         40         50
MVAKVWSRVI LIFIATVMVF ASSQQGDANK VNTASPPGAN GIAYASVVAG
60 70 80 90 100
GSNHVSAAGS VTGDGVQLPN AEVDIDWLEE HLEDSHDYEK GYDLVEQHFN
110 120 130 140 150
KLLVGNNADA SFKVRELASR LILGTLRNNP PVKRLIWDQH PLFVSQVFDL
160 170 180 190 200
YIGNALKQGS GNPLKYPLLK RYLSILLELI PFNRDFRFEE DYKDILDKLY
210 220 230 240 250
TESDVPSDIK IKVLELITLD YSNIKGASGW IDRITNVLTD SEMGLDELHK
260 270 280 290 300
RTFFNAMHAL KSEDPKLKLP TNFLNWLAQE TKERAHNLKL AQAQADDNDL
310 320 330
KVRDLEQEEF DQRLVDSRHS VFGNPMAARM KDPYIVDEL
Length:339
Mass (Da):38,225
Last modified:July 19, 2004 - v1
Checksum:i45FB1C2135123780
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR380952 Genomic DNA. Translation: CAG58945.1.
RefSeqiXP_446021.1. XM_446021.1.

Genome annotation databases

GeneIDi2887649.
KEGGicgr:CAGL0F01089g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR380952 Genomic DNA. Translation: CAG58945.1 .
RefSeqi XP_446021.1. XM_446021.1.

3D structure databases

ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2887649.
KEGGi cgr:CAGL0F01089g.

Phylogenomic databases

InParanoidi Q6FUS3.
KOi K14001.
OrthoDBi EOG7V1G2Q.

Family and domain databases

ProtoNeti Search...

Entry informationi

Entry nameiSIL1_CANGA
AccessioniPrimary (citable) accession number: Q6FUS3
Entry historyi
Integrated into UniProtKB/Swiss-Prot: February 21, 2006
Last sequence update: July 19, 2004
Last modified: October 29, 2014
This is version 53 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3