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Protein

Putative tyrosine-protein phosphatase OCA1

Gene

OCA1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Putative tyrosine-protein phosphatase required for protection against superoxide stress.By similarity

Catalytic activityi

Protein tyrosine phosphate + H2O = protein tyrosine + phosphate.

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei147 – 1471Phosphocysteine intermediateBy similarity

GO - Molecular functioni

Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

Stress response

Names & Taxonomyi

Protein namesi
Recommended name:
Putative tyrosine-protein phosphatase OCA1 (EC:3.1.3.48)
Gene namesi
Name:OCA1
Ordered Locus Names:CAGL0G06578g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428 Componenti: Chromosome G

Organism-specific databases

EuPathDBiFungiDB:CAGL0G06578g.

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 217217Putative tyrosine-protein phosphatase OCA1PRO_0000333390Add
BLAST

Interactioni

Protein-protein interaction databases

STRINGi284593.XP_446646.1.

Structurei

3D structure databases

ProteinModelPortaliQ6FSZ8.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000188365.
InParanoidiQ6FSZ8.
KOiK18043.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FSZ8-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDSPTLEDRE NSIEDCDDDD DNIYINEETE EGHEKVLVTH APQERIVPPL
60 70 80 90 100
NFCPVERYLY RSGQPSPVNF PFLLNLNLKT IVWLANEEPQ DSLLEFCDTH
110 120 130 140 150
KINLQFAAIN PDAGEDDNPW DGLTEHSIIN VLQTIVTKEN YPLLVCCGMG
160 170 180 190 200
RHRTGTVIGC LRRIMGWNLA SVSEEYRRFT GSRGGRILVE LLIEAFDTAL
210
VEIDKKNAPD WLLTSLE
Length:217
Mass (Da):24,687
Last modified:July 19, 2004 - v1
Checksum:i5BC2C66B82CEEDEC
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380953 Genomic DNA. Translation: CAG59573.1.
RefSeqiXP_446646.1. XM_446646.1.

Genome annotation databases

GeneIDi2888220.
KEGGicgr:CAGL0G06578g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380953 Genomic DNA. Translation: CAG59573.1.
RefSeqiXP_446646.1. XM_446646.1.

3D structure databases

ProteinModelPortaliQ6FSZ8.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi284593.XP_446646.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2888220.
KEGGicgr:CAGL0G06578g.

Organism-specific databases

EuPathDBiFungiDB:CAGL0G06578g.

Phylogenomic databases

HOGENOMiHOG000188365.
InParanoidiQ6FSZ8.
KOiK18043.
OrthoDBiEOG7Z0K6V.

Family and domain databases

Gene3Di3.90.190.10. 1 hit.
InterProiIPR029021. Prot-tyrosine_phosphatase-like.
IPR004861. Tyr_Pase_SIW14-like.
[Graphical view]
PfamiPF03162. Y_phosphatase2. 1 hit.
[Graphical view]
SUPFAMiSSF52799. SSF52799. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiOCA1_CANGA
AccessioniPrimary (citable) accession number: Q6FSZ8
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 20, 2008
Last sequence update: July 19, 2004
Last modified: June 24, 2015
This is version 55 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.