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Protein

Sodium/hydrogen exchanger

Gene

CAGL0G07337g

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Protein inferred from homologyi

Functioni

GO - Molecular functioni

  1. sodium:proton antiporter activity Source: InterPro

GO - Biological processi

  1. regulation of pH Source: InterPro
Complete GO annotation...

Keywords - Biological processi

AntiportUniRule annotationSAAS annotation, Ion transport, Sodium transportUniRule annotation, Transport

Keywords - Ligandi

Sodium

Names & Taxonomyi

Protein namesi
Recommended name:
Sodium/hydrogen exchangerUniRule annotation
Gene namesi
Ordered Locus Names:CAGL0G07337gImported
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428 Componenti: Chromosome G

Subcellular locationi

GO - Cellular componenti

  1. integral component of membrane Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Structurei

3D structure databases

ProteinModelPortaliQ6FSW4.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family. [View classification]UniRule annotation

Keywords - Domaini

TransmembraneUniRule annotation

Phylogenomic databases

HOGENOMiHOG000172307.
InParanoidiQ6FSW4.
KOiK12041.
OrthoDBiEOG7SV14M.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FSW4-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MKHYKLYLLL AGVYAETVVG PLDEDLPSME PVADPELSPV TEEMFSSWAL
60 70 80 90 100
FILLFLLISA LWSSYYLSRR RIRAVHETVL SIFYGMVVGL IIRMSPGHYI
110 120 130 140 150
QDTVTFNSSY FFNVLLPPII LNSGYELNQV NFFSNIVSIL TFAIPGTLIS
160 170 180 190 200
AVVLGTILFI WTSLGLEGVN ISFLDALSVG ATLSATDPVT ILSIFNAYKV
210 220 230 240 250
DPKLYTIIFG ESLLNDAISI VMFETCQKFH GQPAKFSSLF AGAGLFLMTF
260 270 280 290 300
SVSLLIGVLI GMLVALILKH THIRRYPQIE SCLILLIAYE SYFFSNGCHM
310 320 330 340 350
SGIVSLLFCG ITLKHYAYYN MSRRTQVTVK YIFQLLARLS ENFIFIYLGL
360 370 380 390 400
ALFTEVELVY KPLLIIVTAI SICVARWCAV FPLSNFVNWI YRVRTLHSIR
410 420 430 440 450
PSVGESIAVP DEIPYNYQVM TFWAGLRGAV GVALAMGLQG EFKFTLLATV
460 470 480 490 500
LVVVVLTVVI FGGTTAGMLE VMNIKTGCVD NGDPEEDEFD IENVGEDPLD
510 520 530 540 550
DEPLQFNANS RNLMRPYTDL PTPVGNVRDF DENDFPSMSA TPDRMSEQAA
560 570 580 590 600
SSQRPSGERT NLKDAIGNML RTDSQWFQNF DEQVLKPVFL DSTSSPMTNR
610
DEGLNSNRDS PRFMSSRK
Length:618
Mass (Da):69,062
Last modified:July 18, 2004 - v1
Checksum:iB387C6C8FFC6020A
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380953 Genomic DNA. Translation: CAG59607.1.
RefSeqiXP_446680.1. XM_446680.1.

Genome annotation databases

GeneIDi2888109.
KEGGicgr:CAGL0G07337g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380953 Genomic DNA. Translation: CAG59607.1.
RefSeqiXP_446680.1. XM_446680.1.

3D structure databases

ProteinModelPortaliQ6FSW4.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2888109.
KEGGicgr:CAGL0G07337g.

Phylogenomic databases

HOGENOMiHOG000172307.
InParanoidiQ6FSW4.
KOiK12041.
OrthoDBiEOG7SV14M.

Family and domain databases

InterProiIPR006153. Cation/H_exchanger.
IPR018422. Cation/H_exchanger_CPA1.
IPR004709. NaH_exchanger.
[Graphical view]
PANTHERiPTHR10110. PTHR10110. 1 hit.
PfamiPF00999. Na_H_Exchanger. 1 hit.
[Graphical view]
PRINTSiPR01084. NAHEXCHNGR.
TIGRFAMsiTIGR00840. b_cpa1. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome evolution in yeasts."
    Genolevures
    Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
    , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L.
    Nature 430:35-44(2003) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65Imported.

Entry informationi

Entry nameiQ6FSW4_CANGA
AccessioniPrimary (citable) accession number: Q6FSW4
Entry historyi
Integrated into UniProtKB/TrEMBL: July 18, 2004
Last sequence update: July 18, 2004
Last modified: February 3, 2015
This is version 68 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.