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Protein

Glutamate decarboxylase

Gene

CAGL0H02585g

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

L-glutamate = 4-aminobutanoate + CO2.UniRule annotation

Cofactori

pyridoxal 5'-phosphateUniRule annotation

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

DecarboxylaseUniRule annotation, Lyase

Keywords - Ligandi

Pyridoxal phosphateUniRule annotation

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamate decarboxylaseUniRule annotation (EC:4.1.1.15UniRule annotation)
Gene namesi
Ordered Locus Names:CAGL0H02585gImported
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)Imported
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428 Componenti: Chromosome H

Organism-specific databases

EuPathDBiFungiDB:CAGL0H02585g.

Interactioni

Protein-protein interaction databases

STRINGi284593.XP_446908.1.

Structurei

3D structure databases

ProteinModelPortaliQ6FS86.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the group II decarboxylase family.UniRule annotation

Phylogenomic databases

HOGENOMiHOG000070228.
InParanoidiQ6FS86.
KOiK01580.
OMAiFLHLGFE.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FS86-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MLHKHTDKQR LPVNIVDHHH IDPCLQDFKL LSKELQDIAS NSEKLKALGS
60 70 80 90 100
KENKESHLLS MKYVIPKEGV PADQAYDMIH NELTLDGNTH LNLASFVNTS
110 120 130 140 150
TTHEVRKLIS ENLTKNLADN DEYPQLIELT QRCISMLSGL WNANPEEEPI
160 170 180 190 200
GCATTGSSEA IMLGGLAMKK MWEKKMKAAG RTDTSKPNII MSSACQVALE
210 220 230 240 250
KFARYFDVEC RLVPVSRKSH HMLDPNLLWD FVDENTIGCF VIMGTTYTGH
260 270 280 290 300
LENVAEVGDV LTAIEKQHPE WANKDIPIHV DGASGGFIVP FAFSREQLKA
310 320 330 340 350
YGVPNWGFDH PRVVSINTSG HKFGLTTPGL GWVLWRDESH LAPELRFRLK
360 370 380 390 400
YLGGVEETFG LNFSRPGFQV VHQYYNFMNL GYDGYRDTFK RSLFVARVFA
410 420 430 440 450
HQILRSPIFN DYFEVVSSIH ESIDGDKVPD AANDYWENPE KYKPGVPLIA
460 470 480 490 500
FKFSDKFQKE YPEVPQALLS HMLRTRGWII PNYPLPHSTD GSDKCEVLRV
510 520 530 540 550
VFRNEMSLDL AQLLLSDIQA VLRKLQGSYS GLKTISHESD SDKRRDYVYK
560 570 580 590
MLLALASPDA DIGEDEDEET KEKKASKKEE IKQRLKRNYR GTC
Length:593
Mass (Da):67,410
Last modified:July 19, 2004 - v1
Checksum:i4FA82C0C253B2AB7
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380954 Genomic DNA. Translation: CAG59841.1.
RefSeqiXP_446908.1. XM_446908.1.

Genome annotation databases

GeneIDi2888533.
KEGGicgr:CAGL0H02585g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380954 Genomic DNA. Translation: CAG59841.1.
RefSeqiXP_446908.1. XM_446908.1.

3D structure databases

ProteinModelPortaliQ6FS86.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi284593.XP_446908.1.

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2888533.
KEGGicgr:CAGL0H02585g.

Organism-specific databases

EuPathDBiFungiDB:CAGL0H02585g.

Phylogenomic databases

HOGENOMiHOG000070228.
InParanoidiQ6FS86.
KOiK01580.
OMAiFLHLGFE.
OrthoDBiEOG7P2Z22.

Family and domain databases

Gene3Di3.40.640.10. 1 hit.
InterProiIPR010107. Glutamate_decarboxylase.
IPR002129. PyrdxlP-dep_de-COase.
IPR015424. PyrdxlP-dep_Trfase.
IPR015421. PyrdxlP-dep_Trfase_major_sub1.
[Graphical view]
PANTHERiPTHR11999:SF1. PTHR11999:SF1. 1 hit.
PfamiPF00282. Pyridoxal_deC. 1 hit.
[Graphical view]
SUPFAMiSSF53383. SSF53383. 1 hit.
TIGRFAMsiTIGR01788. Glu-decarb-GAD. 1 hit.
ProtoNetiSearch...

Publicationsi

  1. "Genome evolution in yeasts."
    Genolevures
    Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S.
    , Beckerich J.M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.F., Straub M.L., Suleau A., Swennene D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic I., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.L.
    Nature 430:35-44(2004) [PubMed] [Europe PMC] [Abstract]
    Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
    Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65Imported.

Entry informationi

Entry nameiQ6FS86_CANGA
AccessioniPrimary (citable) accession number: Q6FS86
Entry historyi
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: June 24, 2015
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteomeImported

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.