Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

D-arabinono-1,4-lactone oxidase

Gene

ALO1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

D-arabinono-1,4-lactone + O2 = dehydro-D-arabinono-1,4-lactone + H2O2.

Cofactori

FADBy similarity

Pathwayi

GO - Molecular functioni

  1. D-arabinono-1,4-lactone oxidase activity Source: UniProtKB-EC
  2. flavin adenine dinucleotide binding Source: InterPro
  3. UDP-N-acetylmuramate dehydrogenase activity Source: InterPro

GO - Biological processi

  1. biosynthetic process Source: InterPro
Complete GO annotation...

Keywords - Molecular functioni

Oxidoreductase

Keywords - Ligandi

FAD, Flavoprotein

Enzyme and pathway databases

UniPathwayiUPA00771; UER00766.

Names & Taxonomyi

Protein namesi
Recommended name:
D-arabinono-1,4-lactone oxidase (EC:1.1.3.37)
Short name:
ALO
Alternative name(s):
L-galactono-gamma-lactone oxidase
Gene namesi
Name:ALO1
Ordered Locus Names:CAGL0H04125g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428 Componenti: Chromosome H

Organism-specific databases

EuPathDBiFungiDB:CAGL0H04125g.

Subcellular locationi

  1. Mitochondrion membrane By similarity

  2. Note: Membrane-embedded.By similarity

GO - Cellular componenti

  1. mitochondrial membrane Source: UniProtKB-SubCell
Complete GO annotation...

Keywords - Cellular componenti

Membrane, Mitochondrion

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 525525D-arabinono-1,4-lactone oxidasePRO_0000128165Add
BLAST

Amino acid modifications

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Modified residuei58 – 581Pros-8alpha-FAD histidineBy similarity

Structurei

3D structure databases

ProteinModelPortaliQ6FS20.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini20 – 195176FAD-binding PCMH-typePROSITE-ProRule annotationAdd
BLAST

Sequence similaritiesi

Contains 1 FAD-binding PCMH-type domain.PROSITE-ProRule annotation

Phylogenomic databases

HOGENOMiHOG000204635.
InParanoidiQ6FS20.
KOiK00107.
OMAiMDCLFSQ.
OrthoDBiEOG7JX3CZ.

Family and domain databases

Gene3Di3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProiIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
IPR030654. Sugar_lactone_oxidase.
[Graphical view]
PfamiPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFiPIRSF000136. LGO_GLO. 1 hit.
SUPFAMiSSF56176. SSF56176. 1 hit.
TIGRFAMsiTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEiPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FS20-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDLKTFGGRR NFVFRNWAGI YSSRPEWYFQ PSSVDEVVEI VKAAKLKNKT
60 70 80 90 100
IVTVGSGHSP SNMCVTDEWM MNLDKMNKLL DFVENEDKTY ADVTIQGGTR
110 120 130 140 150
LYKIHKILRE KGYAMQSLGS ISEQSIGGII STGTHGSSPF HGLVSSTIVN
160 170 180 190 200
LTVVNGKGEV LFLDEKSNPE VFRAATLSLG KIGIIVGATV RVVPAFNIKS
210 220 230 240 250
TQEVIKFETL LEKWDSLWTS SEFIRIWWYP YTRKCILWRG VKTNEPQTKS
260 270 280 290 300
RYSWWGSTLG RFFYQTLLFI STKIYPPLTP YVERFVFRRQ YGEVETLGKG
310 320 330 340 350
DVAIEDSVTG FNMDCLFSQF VDEWGCPMDN GLEVLRSLDH SIAQAAANKD
360 370 380 390 400
FYVHVPVEVR CANTTLPKEQ PETSFRSNTS RGPVYGNLLR PYLDNTPSQC
410 420 430 440 450
SYAPIHSVTN SQLTLYINAT IYRPFHTNAP IHKWFTLFED TMSAAGGKPH
460 470 480 490 500
WAKNFLGSTS FAQGQVKAEG QYQDYEMRGM ATRVKEWYGS DLETFKKVRR
510 520
EQDPDNIFLA NKQWALINGI IDENE
Length:525
Mass (Da):59,716
Last modified:July 19, 2004 - v1
Checksum:i1EA506B8580E3E81
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380954 Genomic DNA. Translation: CAG59907.1.
RefSeqiXP_446974.1. XM_446974.1.

Genome annotation databases

GeneIDi2888523.
KEGGicgr:CAGL0H04125g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380954 Genomic DNA. Translation: CAG59907.1.
RefSeqiXP_446974.1. XM_446974.1.

3D structure databases

ProteinModelPortaliQ6FS20.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2888523.
KEGGicgr:CAGL0H04125g.

Organism-specific databases

EuPathDBiFungiDB:CAGL0H04125g.

Phylogenomic databases

HOGENOMiHOG000204635.
InParanoidiQ6FS20.
KOiK00107.
OMAiMDCLFSQ.
OrthoDBiEOG7JX3CZ.

Enzyme and pathway databases

UniPathwayiUPA00771; UER00766.

Family and domain databases

Gene3Di3.30.43.10. 1 hit.
3.30.465.10. 1 hit.
InterProiIPR007173. ALO.
IPR016169. CO_DH_flavot_FAD-bd_sub2.
IPR016166. FAD-bd_2.
IPR016167. FAD-bd_2_sub1.
IPR010031. FAD_lactone_oxidase.
IPR006094. Oxid_FAD_bind_N.
IPR006093. Oxy_OxRdtase_FAD_BS.
IPR030654. Sugar_lactone_oxidase.
[Graphical view]
PfamiPF04030. ALO. 1 hit.
PF01565. FAD_binding_4. 1 hit.
[Graphical view]
PIRSFiPIRSF000136. LGO_GLO. 1 hit.
SUPFAMiSSF56176. SSF56176. 1 hit.
TIGRFAMsiTIGR01678. FAD_lactone_ox. 1 hit.
PROSITEiPS51387. FAD_PCMH. 1 hit.
PS00862. OX2_COVAL_FAD. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiALO_CANGA
AccessioniPrimary (citable) accession number: Q6FS20
Entry historyi
Integrated into UniProtKB/Swiss-Prot: November 23, 2004
Last sequence update: July 19, 2004
Last modified: April 29, 2015
This is version 74 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  2. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.