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Q6FPF3 (ACH1_CANGA) Reviewed, UniProtKB/Swiss-Prot

Last modified June 11, 2014. Version 57. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Acetyl-CoA hydrolase

EC=3.1.2.1
Alternative name(s):
Acetyl-CoA deacylase
Short name=Acetyl-CoA acylase
Gene names
Name:ACH1
Ordered Locus Names:CAGL0J04268g
OrganismCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) [Complete proteome]
Taxonomic identifier284593 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesmitosporic Nakaseomyces

Protein attributes

Sequence length526 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

Presumably involved in regulating the intracellular acetyl-CoA pool for fatty acid and cholesterol synthesis and fatty acid oxidation By similarity.

Catalytic activity

Acetyl-CoA + H2O = CoA + acetate.

Subcellular location

Cytoplasm By similarity.

Sequence similarities

Belongs to the acetyl-CoA hydrolase/transferase family.

Ontologies

Keywords
   Cellular componentCytoplasm
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processacetyl-CoA metabolic process

Inferred from electronic annotation. Source: InterPro

   Cellular_componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular_functionacetyl-CoA hydrolase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 526526Acetyl-CoA hydrolase
PRO_0000215518

Sequences

Sequence LengthMass (Da)Tools
Q6FPF3 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: D36573740EBAD8FF

FASTA52658,578
        10         20         30         40         50         60 
MTVSKLLKER VRYAPYLAKV KTPEELIPLF KNGQYLGWSG FTGVGTPKAV PDALIKHVED 

        70         80         90        100        110        120 
NNLQGKLRFN LFVGASAGPE ENKWAEHDMI IRRAPHQVGK PIAKAINNGK IQFFDKHLSM 

       130        140        150        160        170        180 
FPQDLTYGYY TRDRTDGKIL DYMIIEATAI KEDGSIVPGP SVGGSPEFIS VSDKVIIEVN 

       190        200        210        220        230        240 
TATPSFEGVH DIDMPVNPPH RVPYPYTKVD QKIGVDSIPV DPERVIAIVE SKTRDQVGPN 

       250        260        270        280        290        300 
TPSDDMSKAI AGNLIEFFRN EVKHGRLPEN LLPLQSGIGN IANAVIEGLT DANFKHLNVW 

       310        320        330        340        350        360 
TEVLQDSFLD LFENGSLDYA TATSIRLTEP GFERVFKNWD FYKSRLCLRS QVVSNNPELI 

       370        380        390        400        410        420 
RRLGVIAMNT PVEADIYAHA NSTNVNGSRM LNGLGGSADF LRNAKLSIMH CPAARPTKVD 

       430        440        450        460        470        480 
PTGISSIVPM VSHVDQTEHD LDVLVTDQGL ADLRGLSPRE RAREIINKCA HPDYKPLLQD 

       490        500        510        520 
YLDRAEHYAT KHGCLHEPHM LKNAFKFHTN LAEKGTMKVE SWDPVE 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR380956 Genomic DNA. Translation: CAG60840.1.
RefSeqXP_447891.1. XM_447891.1.

3D structure databases

ProteinModelPortalQ6FPF3.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2889653.
KEGGcgr:CAGL0J04268g.

Phylogenomic databases

HOGENOMHOG000172597.
KOK01067.
OMAYIPTRRP.
OrthoDBEOG7TQV8M.

Family and domain databases

InterProIPR026888. AcetylCoA_hyd_C.
IPR003702. ActCoA_hydro.
[Graphical view]
PfamPF13336. AcetylCoA_hyd_C. 1 hit.
PF02550. AcetylCoA_hydro. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameACH1_CANGA
AccessionPrimary (citable) accession number: Q6FPF3
Entry history
Integrated into UniProtKB/Swiss-Prot: January 4, 2005
Last sequence update: July 19, 2004
Last modified: June 11, 2014
This is version 57 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families