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Reviewed, UniProtKB/Swiss-Prot Q6FP78 (ADA_CANGA)

Last modified February 9, 2010. Version 39. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

Names and origin

Protein namesRecommended name:
    Adenosine deaminase
    EC=3.5.4.4
Alternative name(s):
    Adenosine aminohydrolase
Gene names
Name: AAH1
Ordered Locus Names: CAGL0J05984g
OrganismCandida glabrata (Yeast) (Torulopsis glabrata) [Complete proteome]
Taxonomic identifier5478 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesmitosporic Nakaseomyces

Protein attributes

Sequence length347 AA.
Sequence statusComplete.
Protein existenceInferred from homology.

General annotation (Comments)

Catalytic activity

Adenosine + H2O = inosine + NH3.

Subcellular location

Cytoplasm By similarity. Nucleus By similarity.

Sequence similarities

Belongs to the adenosine and AMP deaminases family.

Ontologies

Keywords
   Biological processNucleotide metabolism
   Cellular componentCytoplasm
Nucleus
   Molecular functionHydrolase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processpurine ribonucleoside monophosphate biosynthetic process

Inferred from electronic annotation. Source: InterPro

   Cellular componentcytoplasm

Inferred from electronic annotation. Source: UniProtKB-SubCell

nucleus

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functionadenosine deaminase activity

Inferred from electronic annotation. Source: EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 347347Adenosine deaminase
PRO_0000256233

Sites

Active site2041 Potential
Active site2521 Potential
Active site2851 Potential
Active site2861 Potential

Sequences

Sequence LengthMass (Da)Tools
Q6FP78-1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: F48170A9E08B8C9F

FASTA34739,697
        10         20         30         40         50         60 
MVPESFLLEL PKCEHHLHLE GTLEPDLLFP LAKRNNIQLP DHFPQTPEEL AVRYTQFKDL 

        70         80         90        100        110        120 
QDFLDYYYIG TNVLLKEEDF FDLAWAYFTK VSKQGLVHAE LFYDPQSHTT RGVSLETVTR 

       130        140        150        160        170        180 
GFERACKKAH EELGITSKLI MCLLRHLPPQ DCLQTIEEAE QLIKSGVIHG LGLDSAEKPF 

       190        200        210        220        230        240 
PPSLFVECYE RAAKINPELR LTAHAGEEGT HQFVSDALDL LNVTRIDHGV NSKQSEELMA 

       250        260        270        280        290        300 
RLAEQQTLLT VCPLSNVKLQ VVQSVKEIPL QLFLDKNIAF SLNSDDPAYF GGYILDNYYQ 

       310        320        330        340 
VNKDFPDWDF KVWERIAKNG INGSWCEQKR KEELLAKVDA VVAKYTN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR380956 Genomic DNA. Translation: CAG60917.1.
RefSeqXP_447966.1.

3D structure databases

HSSPHSSP built from PDB template 2AMX based on UniProtKB Q7RMV2.
SMRQ6FP78. Positions 8-339.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6FP78.

Genome annotation databases

GeneID2889775.
GenomeReviewsGene locus CAGL0J05984g in contig CR380956_GR.
KEGGcgr:CAGL0J05984g.

Phylogenomic databases

eggNOGfuNOG04795.
HOGENOMHBG630382.
OMAKLIMCLL.
OrthoDBEOG9B2VDF.
PhylomeDBQ6FP78.

Enzyme and pathway databases

BRENDA3.5.4.4. 189220.

Family and domain databases

InterProIPR006650. A/AMP_deam_AS.
IPR001365. A/AMP_deaminase.
IPR006330. A_deaminase.
[Graphical view]
PANTHERPTHR11409. A/AMP_deaminase. 1 hit.
PfamPF00962. A_deaminase. 1 hit.
[Graphical view]
TIGRFAMsTIGR01430. aden_deam. 1 hit.
PROSITEPS00485. A_DEAMINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry nameADA_CANGA
AccessionPrimary (citable) accession number: Q6FP78
Entry history
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 19, 2004
Last modified: February 9, 2010
This is version 39 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents