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Protein

Glycerol-3-phosphate dehydrogenase [NAD(+)] 1

Gene

GPD1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed-Annotation score: Annotation score: 3 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

sn-glycerol 3-phosphate + NAD+ = glycerone phosphate + NADH.

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Binding sitei138NADBy similarity1
Binding sitei161NAD; via amide nitrogenBy similarity1
Binding sitei161SubstrateBy similarity1
Binding sitei194NAD; via amide nitrogenBy similarity1
Active sitei254Proton acceptorBy similarity1
Binding sitei319NADBy similarity1
Binding sitei348NADBy similarity1

Regions

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Nucleotide bindingi50 – 55NADBy similarity6

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionOxidoreductase
LigandNAD

Names & Taxonomyi

Protein namesi
Recommended name:
Glycerol-3-phosphate dehydrogenase [NAD(+)] 1 (EC:1.1.1.8)
Gene namesi
Name:GPD1
Ordered Locus Names:CAGL0K01683g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
Proteomesi
  • UP000002428 Componenti: Chromosome K

Organism-specific databases

CGDiCAL0133949. GPD1.
EuPathDBiFungiDB:CAGL0K01683g.

Subcellular locationi

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001380861 – 400Glycerol-3-phosphate dehydrogenase [NAD(+)] 1Add BLAST400

Proteomic databases

PRIDEiQ6FN96.

Interactioni

GO - Molecular functioni

Protein-protein interaction databases

STRINGi284593.XP_448298.1.

Structurei

3D structure databases

ProteinModelPortaliQ6FN96.
SMRiQ6FN96.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Region

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Regioni319 – 320Substrate bindingBy similarity2

Sequence similaritiesi

Phylogenomic databases

eggNOGiKOG2711. Eukaryota.
COG0240. LUCA.
HOGENOMiHOG000246855.
InParanoidiQ6FN96.
KOiK00006.
OMAiNMIGKGY.
OrthoDBiEOG092C3ZQP.

Family and domain databases

Gene3Di1.10.1040.10. 1 hit.
InterProiView protein in InterPro
IPR008927. 6-PGluconate_DH-like_C_sf.
IPR013328. 6PGD_dom2.
IPR006168. G3P_DH_NAD-dep.
IPR006109. G3P_DH_NAD-dep_C.
IPR017751. G3P_DH_NAD-dep_euk.
IPR011128. G3P_DH_NAD-dep_N.
IPR036291. NAD(P)-bd_dom_sf.
PfamiView protein in Pfam
PF07479. NAD_Gly3P_dh_C. 1 hit.
PF01210. NAD_Gly3P_dh_N. 1 hit.
PIRSFiPIRSF000114. Glycerol-3-P_dh. 1 hit.
PRINTSiPR00077. GPDHDRGNASE.
SUPFAMiSSF48179. SSF48179. 1 hit.
SSF51735. SSF51735. 1 hit.
TIGRFAMsiTIGR03376. glycerol3P_DH. 1 hit.
PROSITEiView protein in PROSITE
PS00957. NAD_G3PDH. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FN96-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSNSAAGRLN QTSHILNESI KNDDISLRRS QPSTTSLQAL EHPFKVTVIG
60 70 80 90 100
SGNWGTTIAK VVAENTALNP HLFVSRVDMW VFEEKIDGKN LTEIINEQHE
110 120 130 140 150
NVKYLPDIKL PENLVANPNL IDSVKGADIL IFNIPHQFLP RIVSNLKNHV
160 170 180 190 200
GPHVRAISCL KGFEVGKKGV QLLSSYVTDE LGIQCGALSG ANLAPEVAKE
210 220 230 240 250
HWSETTVAYH IPKDFRGEGK DVDHKLLKAL FHRPYFHVNV IEDVAGISIA
260 270 280 290 300
GALKNVVALG CGFVEGLGWG NNAAAAIQRV GLGEIIKFGQ MFFPESRVQT
310 320 330 340 350
YYQESAGVAD LITTCSGGRN VRVAKHMAKT GKSALDAEKE LLNGQSAQGI
360 370 380 390 400
ITCKEVHEWL ETCEMTHEFP LFEAVYQIVY NNVPMKNLPD MIEELECIAD
Length:400
Mass (Da):43,988
Last modified:July 19, 2004 - v1
Checksum:iDE850B128571D8E5
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380957 Genomic DNA. Translation: CAG61259.1.
RefSeqiXP_448298.1. XM_448298.1.

Genome annotation databases

EnsemblFungiiCAG61259; CAG61259; CAGL0K01683g.
GeneIDi2890024.
KEGGicgr:CAGL0K01683g.

Similar proteinsi

Entry informationi

Entry nameiGPD1_CANGA
AccessioniPrimary (citable) accession number: Q6FN96
Entry historyiIntegrated into UniProtKB/Swiss-Prot: January 10, 2006
Last sequence update: July 19, 2004
Last modified: November 22, 2017
This is version 93 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families