Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.

Q6FMU7

- SSU72_CANGA

UniProt

Q6FMU7 - SSU72_CANGA

(max 400 entries)x

Your basket is currently empty.

Select item(s) and click on "Add to basket" to create your own collection here
(400 entries max)

Protein

RNA polymerase II subunit A C-terminal domain phosphatase SSU72

Gene

SSU72

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed - Annotation score: 2 out of 5- Protein inferred from homologyi

Functioni

Processively dephosphorylates Ser-5 of the heptad repeats YSPTSPS in the C-terminal domain of the largest RNA polymerase II subunit (RPB1).By similarity
Component of the cleavage and polyadenylation factor (CPF) complex, which plays a key role in polyadenylation-dependent pre-mRNA 3'-end formation and cooperates with cleavage factors including the CFIA complex and NAB4/CFIB. SSU72 is required for 3'-end formation of snoRNAs (By similarity).By similarity

Catalytic activityi

[a protein]-serine/threonine phosphate + H2O = [a protein]-serine/threonine + phosphate.

GO - Molecular functioni

  1. phosphoprotein phosphatase activity Source: UniProtKB-KW

GO - Biological processi

  1. mRNA processing Source: UniProtKB-KW
Complete GO annotation...

Keywords - Molecular functioni

Hydrolase, Protein phosphatase

Keywords - Biological processi

mRNA processing

Names & Taxonomyi

Protein namesi
Recommended name:
RNA polymerase II subunit A C-terminal domain phosphatase SSU72 (EC:3.1.3.16)
Short name:
CTD phosphatase SSU72
Alternative name(s):
Suppressor of SUA7 protein 2 homolog
Gene namesi
Name:SSU72
Ordered Locus Names:CAGL0K05071g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428: Chromosome K

Subcellular locationi

Nucleus By similarity

GO - Cellular componenti

  1. nucleus Source: UniProtKB-KW
Complete GO annotation...

Keywords - Cellular componenti

Nucleus

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 204204RNA polymerase II subunit A C-terminal domain phosphatase SSU72PRO_0000255605Add
BLAST

Interactioni

Subunit structurei

Component of the cleavage and polyadenylation factor (CPF) complex.By similarity

Structurei

3D structure databases

ProteinModelPortaliQ6FMU7.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the SSU72 phosphatase family.Curated

Phylogenomic databases

HOGENOMiHOG000183445.
InParanoidiQ6FMU7.
KOiK15544.
OMAiWQERWPN.
OrthoDBiEOG7GTTG0.

Family and domain databases

InterProiIPR006811. RNA_pol_II_suA.
[Graphical view]
PANTHERiPTHR20383. PTHR20383. 1 hit.
PfamiPF04722. Ssu72. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FMU7 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MDQKQALKFC TVCASNNNRS MESHRILQEA GYEVSSYGTG SAVRLPGLSF
60 70 80 90 100
DKPNVYPFGT PYNDIYNDLL SQSAERYKAN GLLQMLDRNR RLKKAPEKWQ
110 120 130 140 150
EGTKTFDFVF TCEERCFDAV CEDLMNRGGR LNKIVHVINI DIRDDNENAK
160 170 180 190 200
IGGRAILELA NMLNEKVSEC EQNDTLFEDC ILDILTKWQE AHPQLPCLYA

PSYY
Length:204
Mass (Da):23,379
Last modified:July 19, 2004 - v1
Checksum:i4660A18012F677A7
GO

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR380957 Genomic DNA. Translation: CAG61408.1.
RefSeqiXP_448447.1. XM_448447.1.

Genome annotation databases

GeneIDi2890504.
KEGGicgr:CAGL0K05071g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBL
GenBank
DDBJ
Links Updated
CR380957 Genomic DNA. Translation: CAG61408.1 .
RefSeqi XP_448447.1. XM_448447.1.

3D structure databases

ProteinModelPortali Q6FMU7.
ModBasei Search...
MobiDBi Search...

Protocols and materials databases

Structural Biology Knowledgebase Search...

Genome annotation databases

GeneIDi 2890504.
KEGGi cgr:CAGL0K05071g.

Phylogenomic databases

HOGENOMi HOG000183445.
InParanoidi Q6FMU7.
KOi K15544.
OMAi WQERWPN.
OrthoDBi EOG7GTTG0.

Family and domain databases

InterProi IPR006811. RNA_pol_II_suA.
[Graphical view ]
PANTHERi PTHR20383. PTHR20383. 1 hit.
Pfami PF04722. Ssu72. 1 hit.
[Graphical view ]
ProtoNeti Search...

Entry informationi

Entry nameiSSU72_CANGA
AccessioniPrimary (citable) accession number: Q6FMU7
Entry historyi
Integrated into UniProtKB/Swiss-Prot: October 31, 2006
Last sequence update: July 19, 2004
Last modified: October 29, 2014
This is version 52 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3