Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein

Glutamine synthetase

Gene

GLN1

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

ATP + L-glutamate + NH3 = ADP + phosphate + L-glutamine.

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionLigase
LigandATP-binding, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Recommended name:
Glutamine synthetase (EC:6.3.1.2)
Short name:
GS
Alternative name(s):
Glutamate--ammonia ligase
Gene namesi
Name:GLN1
Ordered Locus Names:CAGL0K05357g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
Proteomesi
  • UP000002428 Componenti: Chromosome K

Organism-specific databases

CGDiCAL0134225. GLN1.
EuPathDBiFungiDB:CAGL0K05357g.

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cell wall Cytoskeleton Vacuole Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Keywords - Cellular componenti

Cytoplasm

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
ChainiPRO_00001531521 – 372Glutamine synthetaseAdd BLAST372

Proteomic databases

PRIDEiQ6FMT6.

Interactioni

Subunit structurei

Homooctamer.By similarity

Protein-protein interaction databases

STRINGi284593.XP_448458.1.

Structurei

3D structure databases

ProteinModelPortaliQ6FMT6.
SMRiQ6FMT6.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the glutamine synthetase family.Curated

Phylogenomic databases

eggNOGiKOG0683. Eukaryota.
COG0174. LUCA.
HOGENOMiHOG000061500.
InParanoidiQ6FMT6.
KOiK01915.
OMAiMMPDGVT.
OrthoDBiEOG092C2OM1.

Family and domain databases

Gene3Di3.10.20.70. 1 hit.
3.30.590.10. 1 hit.
InterProiView protein in InterPro
IPR008147. Gln_synt_b-grasp.
IPR014746. Gln_synth/guanido_kin_cat_dom.
IPR008146. Gln_synth_cat_dom.
IPR027303. Gln_synth_gly_rich_site.
IPR027302. Gln_synth_N_conserv_site.
PfamiView protein in Pfam
PF00120. Gln-synt_C. 1 hit.
PF03951. Gln-synt_N. 1 hit.
SMARTiView protein in SMART
SM01230. Gln-synt_C. 1 hit.
SUPFAMiSSF54368. SSF54368. 1 hit.
PROSITEiView protein in PROSITE
PS00180. GLNA_1. 1 hit.
PS00181. GLNA_ATP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FMT6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MHEHSVEKTQ ILQKYLELPQ NGKVIAEYVW VDGTGNLRSK ARTLNKVITS
60 70 80 90 100
IEQLPEWNFD GSSTNQAPGY DSDIYLKPVA FYPDPFRRGD NITVLAECFN
110 120 130 140 150
SDGTPNKFNH RHEANKLFQA HKDEEIWFGI EQEYTLFDMY DNVYAWPKGG
160 170 180 190 200
YPAPQGPYYC GVGAGKVYAR DVIEAHYRAC LYAGINISGI NAEVMPSQWE
210 220 230 240 250
FQVGPCEGIS MGDQLWMARY FLHRVAEEFG VKISFHPKPL KGDWNGAGCH
260 270 280 290 300
TNVSTKDMRV PGGMKYIEQA IEKLSKRHNE HIKLYGADNE QRLTGRHETA
310 320 330 340 350
SMTSFSSGVA NRGASIRIPR PVAKEGFGYF EDRRPASNID PYLVTGIMCE
360 370
TVCGAIENAN MSKEYERETN EQ
Length:372
Mass (Da):42,106
Last modified:July 19, 2004 - v1
Checksum:i3F8F70E3EEBE04A6
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380957 Genomic DNA. Translation: CAG61419.1.
RefSeqiXP_448458.1. XM_448458.1.

Genome annotation databases

EnsemblFungiiCAG61419; CAG61419; CAGL0K05357g.
GeneIDi2890482.
KEGGicgr:CAGL0K05357g.

Similar proteinsi

Entry informationi

Entry nameiGLNA_CANGA
AccessioniPrimary (citable) accession number: Q6FMT6
Entry historyiIntegrated into UniProtKB/Swiss-Prot: October 11, 2004
Last sequence update: July 19, 2004
Last modified: September 27, 2017
This is version 80 of the entry and version 1 of the sequence. See complete history.
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. SIMILARITY comments
    Index of protein domains and families