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Reviewed, UniProtKB/Swiss-Prot Q6FMG7 (CCPR_CANGA)

Last modified November 3, 2009. Version 44. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents

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Names and origin

Protein namesRecommended name:
    Cytochrome c peroxidase, mitochondrial
      Short name=CCP
    EC=1.11.1.5
Gene names
Ordered Locus Names: CAGL0K08184g
OrganismCandida glabrata (Yeast) (Torulopsis glabrata) [Complete proteome]
Taxonomic identifier5478 [NCBI]
Taxonomic lineageEukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Nakaseomyces › mitosporic Nakaseomyces

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Protein attributes

Sequence length357 AA.
Sequence statusComplete.
Sequence processingThe displayed sequence is further processed into a mature form.
Protein existenceInferred from homology.

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General annotation (Comments)

Function

Destroys radicals which are normally produced within the cells and which are toxic to biological systems By similarity.

Catalytic activity

2 ferrocytochrome c + H2O2 = 2 ferricytochrome c + 2 H2O.

Cofactor

Binds 1 heme B (iron-protoporphyrin IX) group per subunit By similarity.

Subunit structure

Forms a one-to-one complex with cytochrome c By similarity.

Subcellular location

Mitochondrion matrix By similarity.

Sequence similarities

Belongs to the peroxidase family. Cytochrome c peroxidase subfamily.

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Ontologies

Keywords
   Cellular componentMitochondrion
   DomainTransit peptide
   LigandHeme
Iron
Metal-binding
   Molecular functionOxidoreductase
Peroxidase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological processoxidation reduction

Inferred from electronic annotation. Source: UniProtKB-KW

response to oxidative stress

Inferred from electronic annotation. Source: InterPro

   Cellular componentmitochondrial matrix

Inferred from electronic annotation. Source: UniProtKB-SubCell

   Molecular functioncytochrome-c peroxidase activity

Inferred from electronic annotation. Source: EC

heme binding

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Transit peptide1 – 2323Mitochondrion Potential
Chain24 – 357334Cytochrome c peroxidase, mitochondrial
PRO_0000045288

Regions

Compositional bias49 – 557Poly-Asn
Compositional bias60 – 678Poly-Ala

Sites

Active site1161Proton acceptor By similarity
Active site2551Tryptophan radical intermediate By similarity
Metal binding2391Iron (heme axial ligand)
Site1121Transition state stabilizer By similarity

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Sequences

Sequence LengthMass (Da)Tools
Q6FMG7-1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 721EAC06CEE4552F

FASTA35740,007
        10         20         30         40         50         60 
MSATALRIAP IASRTFQRRL GYLLAGVATG AAATVAYKAQ KNNNYYKYNN NNNNNSGFKA 

        70         80         90        100        110        120 
GALAAAAGVV HLAHEEDKKT ADYQKVYNLI AERLRDDDEY DNYIGYGPVL VRLAWHSSGT 

       130        140        150        160        170        180 
WDKNDNTGGS YGGTYRYKKE SQDPSNAGLE NAAKFLEPVK KQFPWISYGD LYTLGGVVGI 

       190        200        210        220        230        240 
QELQGPKIPW RSGRTDLPED MTPDNGRLPD GDKDANYVRN FYKRLDFNDR EVVALLGAHA 

       250        260        270        280        290        300 
LGKTHLKNSG FEGPWGAANN IFTNEFYLNL LNEDWKLEKN DAGNLQYNSP KGYMMLPTDY 

       310        320        330        340        350 
ALIQDSNYLK IVKEYAADQD AFFRDFSKAF AALLERGIDF PKNQPVHIFK TLDEQGL

« Hide

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Cross-references

Sequence databases

CR380957 Genomic DNA. Translation: CAG61540.1.
RefSeqXP_448577.1.

3D structure databases

SMRQ6FMG7. Positions 69-357.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6FMG7.

Protein family/group databases

PeroxiBase2366. CglCcP01.

Genome annotation databases

GeneID2890345.
GenomeReviewsGene locus CAGL0K08184g in contig CR380957_GR.
KEGGcgr:CAGL0K08184g.

Phylogenomic databases

HOGENOMQ6FMG7.
OMAHALGKTH.

Enzyme and pathway databases

BRENDA1.11.1.5. 189220.

Family and domain databases

InterProIPR002207. Asc_perxdse.
IPR002016. Haem_peroxidase_pln/fun/bac.
IPR019794. Peroxidases_AS.
IPR019793. Peroxidases_heam-ligand_BS.
[Graphical view]
PfamPF00141. peroxidase. 1 hit.
[Graphical view]
PRINTSPR00459. ASPEROXIDASE.
PR00458. PEROXIDASE.
PROSITEPS00435. PEROXIDASE_1. 1 hit.
PS00436. PEROXIDASE_2. 1 hit.
PS50873. PEROXIDASE_4. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameCCPR_CANGA
AccessionPrimary (citable) accession number: Q6FMG7
Entry history
Integrated into UniProtKB/Swiss-Prot: December 20, 2005
Last sequence update: July 19, 2004
Last modified: November 3, 2009
This is version 44 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation projectFPAP (Fungal Proteome Annotation Project)

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Relevant documents

SIMILARITY comments

Index of protein domains and families

Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequence annotation (Features) · Sequences · References · Cross-references · Entry information · Relevant documents