Q6FLK1 (Q6FLK1_CANGA) Unreviewed, UniProtKB/TrEMBL

Names and origin

Protein names

Recommended name:
Nicotinate phosphoribosyltransferase RuleBase RU003838
EC=2.4.2.11 RuleBase RU003838

Gene names

Ordered Locus Names:

CAGL0L02805g

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) [Complete proteome]

Taxonomic identifier

284593 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Nakaseomyces › mitosporic Nakaseomyces

Protein attributes

Sequence length	431 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	Nicotinate D-ribonucleotide + diphosphate = nicotinate + 5-phospho-alpha-D-ribose 1-diphosphate. RuleBase RU003838
Pathway	Cofactor biosynthesis; NAD(+) biosynthesis; nicotinate ribonucleotide from nicotinate: step 1/1. RuleBase RU003838
Sequence similarities	Belongs to the NAPRTase family. RuleBase RU003838

Ontologies

Keywords
Biological process	Pyridine nucleotide biosynthesis RuleBase RU003838
Molecular function	Glycosyltransferase RuleBase RU003838 Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	NAD biosynthetic process Inferred from electronic annotation. Source: InterPro nicotinate nucleotide biosynthetic process Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: InterPro
Molecular function	nicotinate phosphoribosyltransferase activity Inferred from electronic annotation. Source: EC nicotinate-nucleotide diphosphorylase (carboxylating) activity Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequences

	Sequence		Length	Mass (Da)
	Q6FLK1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: BF3EC29C6F542671	FASTA	431	49,340
	10 20 30 40 50 60 MSSMTPAITS LLDTDMYKIT MHAAVFTNFP DARVVYKFTN RTAQFHFNKR AVDWIKEQFR 70 80 90 100 110 120 LLGDLTFTHD DVEYLAREIP FLPAKYLHYI ENGFTLKPDE QIELDCQEIK GKEDQYDLHI 130 140 150 160 170 180 LVKGLWIDTI LYEIPILALL SEAYFKFVDT DWDYENQLSN AKEKALRLFE NNLSFSEFGT 190 200 210 220 230 240 RRRRSFKTQD LVMEGIMQAV KENPEKYRPL LLGTSNILFA KKYGVKPIGT VAHEWIMGIA 250 260 270 280 290 300 SITGDYPETN RIAMDYWIKT FGKEHAGLAL TDTFGTDDFL KSFKPPYSDY YIGVRQDSGD 310 320 330 340 350 360 PIKYTEKIAH HFHDVLKLPK FSKFICYSDS LNIDKAIEYG KVAEAHGIKS TFGIGTNFTN 370 380 390 400 410 420 DFHKKSDPSV KSAPLNIVIK LLEVNGNHSI KISDNAGKNM GDPDTVKKVK EQLGYVERQW 430 AGGNEAHRSA A

References

[1]

"Genome evolution in yeasts." Genolevures Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR380958 Genomic DNA. Translation: CAG61863.1.
RefSeq	XP_448893.1. XM_448893.1.
3D structure databases
ProteinModelPortal	Q6FLK1.
SMR	Q6FLK1. Positions 6-420.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2890868.
GenomeReviews	Gene locus CAGL0L02805g in contig CR380958_GR.
KEGG	cgr:CAGL0L02805g.
Phylogenomic databases
eggNOG	fuNOG05269.
HOGENOM	HBG325503.
OMA	HQFPQTH.
OrthoDB	EOG479JGB.
Family and domain databases
HAMAP	MF_00570. NAPRTase. [Tree]
InterPro	IPR006406. Nic_PRibTrfase. IPR015977. Nic_PRibTrfase-like. IPR007229. Nic_PRibTrfase-rel. IPR002638. Quinolinate_PRibosylTrfase_C. [Graphical view]
KO	K00763.
PANTHER	PTHR11098:SF1. NAPRTase. 1 hit.
Pfam	PF04095. NAPRTase. 1 hit. [Graphical view]
PIRSF	PIRSF000484. NAPRT. 1 hit.
SUPFAM	SSF51690. Q_phspho_trans. 1 hit.
TIGRFAMs	TIGR01514. NAPRTase. 1 hit.
ProtoNet	Search...

Entry information

Entry name

Q6FLK1_CANGA

Accession

Primary (citable) accession number: Q6FLK1

Entry history

Integrated into UniProtKB/TrEMBL:	July 19, 2004
Last sequence update:	July 19, 2004
Last modified:	December 14, 2011
This is version 49 of the entry and version 1 of the sequence. [Complete history]

Entry status

Unreviewed (UniProtKB/TrEMBL)