Q6FLF8 (RPIA_CANGA) Reviewed, UniProtKB/Swiss-Prot

Names and origin

Protein names

Recommended name:
Ribose-5-phosphate isomerase
EC=5.3.1.6

Alternative name(s):
D-ribose-5-phosphate ketol-isomerase
Phosphoriboisomerase

Gene names

Name:	RKI1
Ordered Locus Names:	CAGL0L03740g

Organism

Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) [Complete proteome]

Taxonomic identifier

284593 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Nakaseomyces › mitosporic Nakaseomyces

Protein attributes

Sequence length	260 AA.
Sequence status	Complete.
Protein existence	Inferred from homology

General annotation (Comments)

Catalytic activity	D-ribose 5-phosphate = D-ribulose 5-phosphate.
Pathway	Carbohydrate degradation; pentose phosphate pathway; D-ribose 5-phosphate from D-ribulose 5-phosphate (non-oxidative stage): step 1/1.
Subcellular location	Cytoplasm Potential.
Sequence similarities	Belongs to the ribose 5-phosphate isomerase family.

Ontologies

Keywords
Cellular component	Cytoplasm
Molecular function	Isomerase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	pentose-phosphate shunt, non-oxidative branch Inferred from electronic annotation. Source: InterPro
Cellular component	cytoplasm Inferred from electronic annotation. Source: UniProtKB-SubCell
Molecular function	ribose-5-phosphate isomerase activity Inferred from electronic annotation. Source: EC
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 260	260	Ribose-5-phosphate isomerase		PRO_0000339885

Sequences

	Sequence		Length	Mass (Da)
	Q6FLF8 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: D61966268ECD9216	FASTA	260	28,519
	10 20 30 40 50 60 MSYTPLPNIN DFPTLGNPLE DAKRAAAYRA VDENLNFDEH RIIGVGSGST VVYVAERIGQ 70 80 90 100 110 120 YLKDEKYHDK VSKFICIPTG YQSRNLIQDN GLILGSIEQH PHVDIAFDGA DEVDHNLQLI 130 140 150 160 170 180 KGGGACLFQE KLVSTSAKIF IVVADSRKKS DTNLGINWKR GVPIEIVPSA WSRVQHDLTS 190 200 210 220 230 240 ILHANSAPVR QGGSAKAGPV VTDNMNFLID ADFGEIQDPK ALHEQIKMLV GVVETGLFID 250 260 NAHRAYFGKP DGSVEVIDKK

References

[1]

"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR380958 Genomic DNA. Translation: CAG61906.1.
RefSeq	XP_448936.1. XM_448936.1.
3D structure databases
HSSP	HSSP built from PDB template 1XTZ based on UniProtKB Q12189.
ProteinModelPortal	Q6FLF8.
SMR	Q6FLF8. Positions 20-259.
ModBase	Search...
Protocols and materials databases
StructuralBiologyKnowledgebase	Search...
Genome annotation databases
GeneID	2890542.
GenomeReviews	Gene locus CAGL0L03740g in contig CR380958_GR.
KEGG	cgr:CAGL0L03740g.
Phylogenomic databases
eggNOG	fuNOG05297.
HOGENOM	HBG515603.
OMA	IVCIPTS.
OrthoDB	EOG4M68SS.
Family and domain databases
InterPro	IPR004788. Ribose5P_isomerase_typA. [Graphical view]
KO	K01807.
PANTHER	PTHR11934. RpiA. 1 hit.
Pfam	PF06026. Rib_5-P_isom_A. 1 hit. [Graphical view]
TIGRFAMs	TIGR00021. RpiA. 1 hit.
ProtoNet	Search...

Entry information

Entry name

RPIA_CANGA

Accession

Primary (citable) accession number: Q6FLF8

Entry history

Integrated into UniProtKB/Swiss-Prot:	June 10, 2008
Last sequence update:	July 19, 2004
Last modified:	December 14, 2011
This is version 53 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation program

Fungal Protein Annotation Program