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Q6FKY1 (PGK_CANGA) Reviewed, UniProtKB/Swiss-Prot

Last modified February 19, 2014. Version 66. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (2) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein attributes

Sequence length416 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Catalytic activity

ATP + 3-phospho-D-glycerate = ADP + 3-phospho-D-glyceroyl phosphate. HAMAP-Rule MF_00145

Pathway

Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 2/5. HAMAP-Rule MF_00145

Subunit structure

Monomer By similarity. HAMAP-Rule MF_00145

Subcellular location

Cytoplasm By similarity HAMAP-Rule MF_00145.

Sequence similarities

Belongs to the phosphoglycerate kinase family.

Ontologies

Keywords
   Biological processGlycolysis
   Cellular componentCytoplasm
   LigandATP-binding
Nucleotide-binding
   Molecular functionKinase
Transferase
   Technical termComplete proteome
Gene Ontology (GO)
   Biological_processglycolysis

Inferred from electronic annotation. Source: UniProtKB-UniPathway

   Cellular_componentcytosol

Inferred from direct assay PubMed 21085892. Source: CGD

   Molecular_functionATP binding

Inferred from electronic annotation. Source: UniProtKB-KW

phosphoglycerate kinase activity

Inferred from electronic annotation. Source: UniProtKB-EC

Complete GO annotation...

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 416416Phosphoglycerate kinase HAMAP-Rule MF_00145
PRO_0000145877

Regions

Nucleotide binding371 – 3744ATP By similarity
Region24 – 263Substrate binding By similarity
Region63 – 664Substrate binding By similarity

Sites

Binding site391Substrate By similarity
Binding site1221Substrate By similarity
Binding site1691Substrate By similarity
Binding site2181ATP By similarity
Binding site3111ATP; via carbonyl oxygen By similarity
Binding site3421ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6FKY1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 1510C01064D0574A

FASTA41644,617
        10         20         30         40         50         60 
MSLSSKLTVQ DLELKDKRVF IRVDFNVPLD GKKITSNQRI VAALPTIKYV LEHNPRYVVL 

        70         80         90        100        110        120 
ASHLGRPNGE RNEKYSLAPV AEELQSLLGK PVTFLNDCVG SEVDSAVKAS APGSVILLEN 

       130        140        150        160        170        180 
LRYHIEEEGS RKVDGQKVKA SAEDVAKFRK ELCSLADVYI NDAFGTAHRA HSSMVGFDLP 

       190        200        210        220        230        240 
QRAAGFLLTK ELQYFGKALE NPTRPFLAIL GGAKVADKIQ LIDNLLDKVD SIIIGGGMAF 

       250        260        270        280        290        300 
TFKKVLENAE IGDSIFDKAG AEIVPKLMEK AKAKGVEVVL PVDFVIADAF SADANTKIVS 

       310        320        330        340        350        360 
DKEGIPAGWQ GLDNGPESRK LFAATIAKAK TIVWNGPPGV FEFEKFASGT KAMLDEVVKS 

       370        380        390        400        410 
STSGNTVIIG GGDTATVAKK YGVTDKISHV STGGGASLEL LEGKELPGVA FLSEKN 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR380958 Genomic DNA. Translation: CAG62083.1.
RefSeqXP_449113.1. XM_449113.1.

3D structure databases

ProteinModelPortalQ6FKY1.
SMRQ6FKY1. Positions 2-415.
ModBaseSearch...
MobiDBSearch...

Proteomic databases

PRIDEQ6FKY1.

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2891002.
KEGGcgr:CAGL0L07722g.

Phylogenomic databases

KOK00927.
OMAGLDCGEK.
OrthoDBEOG71K6D7.

Enzyme and pathway databases

UniPathwayUPA00109; UER00185.

Family and domain databases

Gene3D3.40.50.1260. 1 hit.
3.40.50.1270. 1 hit.
HAMAPMF_00145. Phosphoglyc_kinase.
InterProIPR001576. Phosphoglycerate_kinase.
IPR015901. Phosphoglycerate_kinase_C.
IPR015911. Phosphoglycerate_kinase_CS.
IPR015824. Phosphoglycerate_kinase_N.
[Graphical view]
PANTHERPTHR11406. PTHR11406. 1 hit.
PfamPF00162. PGK. 1 hit.
[Graphical view]
PIRSFPIRSF000724. Pgk. 1 hit.
PRINTSPR00477. PHGLYCKINASE.
SUPFAMSSF53748. SSF53748. 1 hit.
PROSITEPS00111. PGLYCERATE_KINASE. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePGK_CANGA
AccessionPrimary (citable) accession number: Q6FKY1
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: July 19, 2004
Last modified: February 19, 2014
This is version 66 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families

PATHWAY comments

Index of metabolic and biosynthesis pathways