Skip Header

You are using a version of Internet Explorer that may not display all features of this website. Please upgrade to a modern browser.
Contribute Send feedback
Read comments (?) or add your own

Q6FKD4 (PHO85_CANGA) Reviewed, UniProtKB/Swiss-Prot

Last modified April 16, 2014. Version 69. Feed History...

Clusters with 100%, 90%, 50% identity | Documents (1) | Third-party data text xml rdf/xml gff fasta
to top of pageNames·Attributes·General annotation·Ontologies·Sequence annotation·Sequences·References·Cross-refs·Entry info·DocumentsCustomize order

Names and origin

Protein namesRecommended name:
Negative regulator of the PHO system

EC=2.7.11.22
Alternative name(s):
Serine/threonine-protein kinase PHO85
Gene names
Name:PHO85
Ordered Locus Names:CAGL0L12474g
OrganismCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata) [Complete proteome]
Taxonomic identifier284593 [NCBI]
Taxonomic lineageEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesmitosporic Nakaseomyces

Protein attributes

Sequence length302 AA.
Sequence statusComplete.
Protein existenceInferred from homology

General annotation (Comments)

Function

When phosphate concentrations are high it phosphorylates the PHO4 transcription factor thus establishing repression By similarity.

Catalytic activity

ATP + a protein = ADP + a phosphoprotein.

Subunit structure

Interacts with a number of cyclins By similarity.

Sequence similarities

Belongs to the protein kinase superfamily. CMGC Ser/Thr protein kinase family. CDC2/CDKX subfamily.

Contains 1 protein kinase domain.

Sequence annotation (Features)

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifier

Molecule processing

Chain1 – 302302Negative regulator of the PHO system
PRO_0000086517

Regions

Domain6 – 296291Protein kinase
Nucleotide binding12 – 209ATP By similarity

Sites

Active site1321Proton acceptor By similarity
Binding site351ATP By similarity

Sequences

Sequence LengthMass (Da)Tools
Q6FKD4 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 79706E049D13B7B5

FASTA30234,488
        10         20         30         40         50         60 
MSSSQFKQLE KLGNGTYATV YKGLNKSTGV YVALKEVKLD SEEGTPSTAI REISLMKELK 

        70         80         90        100        110        120 
HDNIVRLYDV IHTENKLTLV FEYMDNDLKK YMDSRTVGNA PRGLEMNLVK YFQWQLLEGL 

       130        140        150        160        170        180 
AFCHENKILH RDLKPQNLLI TKRGQLKLGD FGLARAFGIP VNTFSSEVVT LWYRAPDVLM 

       190        200        210        220        230        240 
GSRTYSTSID IWSCGCILAE MITGKPLFPG TNDEEQLKLI FDKMGTPNET TWPGVTSLPK 

       250        260        270        280        290        300 
YNPNFQQRLP KDLKAELQPY VKEPLDDNVI DLLHGLLQLN PDMRLSAKQA LLHPWFSEYY 


ES 

« Hide

Cross-references

Sequence databases

EMBL
GenBank
DDBJ
CR380958 Genomic DNA. Translation: CAG62284.1.
RefSeqXP_449310.1. XM_449310.1.

3D structure databases

ProteinModelPortalQ6FKD4.
SMRQ6FKD4. Positions 18-300.
ModBaseSearch...
MobiDBSearch...

Protocols and materials databases

StructuralBiologyKnowledgebaseSearch...

Genome annotation databases

GeneID2890701.
KEGGcgr:CAGL0L12474g.

Phylogenomic databases

KOK06655.
OMAQVPQNAY.
OrthoDBEOG7K3TWD.

Family and domain databases

InterProIPR011009. Kinase-like_dom.
IPR000719. Prot_kinase_dom.
IPR017441. Protein_kinase_ATP_BS.
IPR002290. Ser/Thr_dual-sp_kinase_dom.
IPR008271. Ser/Thr_kinase_AS.
[Graphical view]
PfamPF00069. Pkinase. 1 hit.
[Graphical view]
SMARTSM00220. S_TKc. 1 hit.
[Graphical view]
SUPFAMSSF56112. SSF56112. 1 hit.
PROSITEPS00107. PROTEIN_KINASE_ATP. 1 hit.
PS50011. PROTEIN_KINASE_DOM. 1 hit.
PS00108. PROTEIN_KINASE_ST. 1 hit.
[Graphical view]
ProtoNetSearch...

Entry information

Entry namePHO85_CANGA
AccessionPrimary (citable) accession number: Q6FKD4
Entry history
Integrated into UniProtKB/Swiss-Prot: September 27, 2004
Last sequence update: July 19, 2004
Last modified: April 16, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Relevant documents

SIMILARITY comments

Index of protein domains and families