Reviewed, UniProtKB/Swiss-Prot Q6FJV0 (GLGB_CANGA)

Names and origin

Protein names

Recommended name:
    1,4-alpha-glucan-branching enzyme
    EC=2.4.1.18
Alternative name(s):
    Glycogen-branching enzyme

Gene names

Name:	GLC3
Ordered Locus Names:	CAGL0M03377g

Organism

Candida glabrata (Yeast) (Torulopsis glabrata) [Complete proteome]

Taxonomic identifier

5478 [NCBI]

Taxonomic lineage

Eukaryota › Fungi › Dikarya › Ascomycota › Saccharomycotina › Saccharomycetes › Saccharomycetales › Saccharomycetaceae › Nakaseomyces › mitosporic Nakaseomyces

Protein attributes

Sequence length	706 AA.
Sequence status	Complete.
Protein existence	Inferred from homology.

General annotation (Comments)

Catalytic activity	Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.
Pathway	Glycan biosynthesis; glycogen biosynthesis.
Sequence similarities	Belongs to the glycosyl hydrolase 13 family.

Ontologies

Keywords
Biological process	Glycogen biosynthesis
Molecular function	Glycosyltransferase Transferase
Technical term	Complete proteome
Gene Ontology (GO)
Biological process	glycogen biosynthetic process Inferred from electronic annotation. Source: UniProtKB-KW
Molecular function	1,4-alpha-glucan branching enzyme activity Inferred from electronic annotation. Source: EC cation binding Inferred from electronic annotation. Source: InterPro hydrolase activity, hydrolyzing O-glycosyl compounds Inferred from electronic annotation. Source: InterPro
Complete GO annotation...

Sequence annotation (Features)

	Feature key	Position(s)	Length	Description	Graphical view	Feature identifier
Molecule processing
	Chain	1 – 706	706	1,4-alpha-glucan-branching enzyme		PRO_0000188779
Sites
	Active site	250	1	By similarity
	Active site	285	1	By similarity
	Active site	290	1	By similarity
	Active site	356	1	By similarity
	Active site	358	1	By similarity
	Active site	419	1	By similarity
	Active site	487	1	By similarity
	Active site	488	1	By similarity

Sequences

	Sequence		Length	Mass (Da)
	Q6FJV0-1 [UniParc]. Last modified July 19, 2004. Version 1. Checksum: 18872CAADBCD2A87	FASTA	706	81,044
	10 20 30 40 50 60 MSLTKIPENV QGAVSIDPWL EPFADVLSER RYLADKWLYD IKHATPDGSE QSLVDFARNA 70 80 90 100 110 120 YKTYGLHANQ QTKEIVYREW APNAQRAFLV GEFNNWNEES HEMKHKDEFG VFSITLAPLE 130 140 150 160 170 180 NGDFAIPHDS KIKVMFVLPD GSKVYRIPAW ITRATQPSKE TAQKYGPTYE GRFWNPPNSY 190 200 210 220 230 240 QFKHQRPKFN LANDSIKIYE AHIGISSPEP KVASYKEFTQ NVLPRIKHLG YDAIQLMAIM 250 260 270 280 290 300 EHAYYASFGY QVTNFFAISS RYGTPEDLKE LIDTAHSMGI LVLLDVIHSH ASKNSEDGLN 310 320 330 340 350 360 MFDGSDHQYF HSLTSGRGEH PLWDSRLFNY GSFEVQRFLL ANLAYYIDVY QFDGFRFDGV 370 380 390 400 410 420 TSMLYLHHGV GAGGAFSGDY NEYLSRDRSG VDHEALAYLM LANDLVHDLL PESAVTIAED 430 440 450 460 470 480 VSGYPTLCLP RTAGGGGFDY RLAMALPDMW IKLLKTKQDD DWDMGHIVHT LTNRRHGEKV 490 500 510 520 530 540 VAYCESHDQA LVGDKTLAFW LMDAAMYTDM TVLKEPTLVI DRGIALHKMI RLITHSLGGE 550 560 570 580 590 600 AYLNFEGNEF GHPEWLDFPR VGNNDSYHYA RRQFNLVDDD LLRYRHLNEF DAAMQNCESK 610 620 630 640 650 660 HQWLNTPQAY VSLKHEVDKV IAFERNGHLF VFNFHPTQSF TDYRIGVDVA GTYKIVLNTD 670 680 690 700 RAEFGGHNRI DEAQEFFTTD LEWNNRRNFI QVYIPSRTAI VLTRQM

References

[1]

"Genome evolution in yeasts." Dujon B., Sherman D., Fischer G., Durrens P., Casaregola S., Lafontaine I., de Montigny J., Marck C., Neuveglise C., Talla E., Goffard N., Frangeul L., Aigle M., Anthouard V., Babour A., Barbe V., Barnay S., Blanchin S. , Beckerich J.-M., Beyne E., Bleykasten C., Boisrame A., Boyer J., Cattolico L., Confanioleri F., de Daruvar A., Despons L., Fabre E., Fairhead C., Ferry-Dumazet H., Groppi A., Hantraye F., Hennequin C., Jauniaux N., Joyet P., Kachouri R., Kerrest A., Koszul R., Lemaire M., Lesur I., Ma L., Muller H., Nicaud J.-M., Nikolski M., Oztas S., Ozier-Kalogeropoulos O., Pellenz S., Potier S., Richard G.-F., Straub M.-L., Suleau A., Swennen D., Tekaia F., Wesolowski-Louvel M., Westhof E., Wirth B., Zeniou-Meyer M., Zivanovic Y., Bolotin-Fukuhara M., Thierry A., Bouchier C., Caudron B., Scarpelli C., Gaillardin C., Weissenbach J., Wincker P., Souciet J.-L. Nature 430:35-44(2004) [PubMed: 15229592] [Abstract] Cited for: NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA]. Strain: ATCC 2001 / CBS 138 / IFO 0622 / NRRL Y-65.

Cross-references

Sequence databases
EMBL GenBank DDBJ	CR380959 Genomic DNA. Translation: CAG62470.1.
RefSeq	XP_449494.1.
3D structure databases
ModBase	Search...
Protein-protein interaction databases
STRING	Q6FJV0.
Genome annotation databases
GeneID	2891502.
GenomeReviews	Gene locus CAGL0M03377g in contig CR380959_GR.
KEGG	cgr:CAGL0M03377g.
Phylogenomic databases
eggNOG	fuNOG05596.
HOGENOM	HBG302308.
OMA	YNEYLSR.
OrthoDB	EOG9MCZGQ.
PhylomeDB	Q6FJV0.
Enzyme and pathway databases
BRENDA	2.4.1.18. 189220.
Family and domain databases
InterPro	IPR006048. A-amylase_b_C. IPR013780. Glyco_hydro_13_b. IPR006047. Glyco_hydro_13_cat_dom. IPR004193. Glyco_hydro_13_N. IPR017853. Glyco_hydro_catalytic_core. IPR013781. Glyco_hydro_sg_catalytic. IPR013783. Ig-like_fold. IPR014756. Ig_E-set. [Graphical view]
Gene3D	G3DSA:2.60.40.1180. Glyco_hydro_13_b. 1 hit. G3DSA:3.20.20.80. Glyco_hydro_cat. 1 hit. G3DSA:2.60.40.10. Ig-like_fold. 1 hit.
Pfam	PF00128. Alpha-amylase. 1 hit. PF02806. Alpha-amylase_C. 1 hit. PF02922. CBM_48. 1 hit. [Graphical view]
ProtoNet	Search...

Entry information

Entry name

GLGB_CANGA

Accession

Primary (citable) accession number: Q6FJV0

Entry history

Integrated into UniProtKB/Swiss-Prot:	May 10, 2005
Last sequence update:	July 19, 2004
Last modified:	January 19, 2010
This is version 44 of the entry and version 1 of the sequence. [Complete history]

Entry status

Reviewed (UniProtKB/Swiss-Prot)

Annotation project

FPAP (Fungal Proteome Annotation Project)