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Protein

1,4-alpha-glucan-branching enzyme

Gene

GLC3

Organism
Candida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Status
Reviewed-Annotation score: Annotation score: 2 out of 5-Protein inferred from homologyi

Functioni

Catalytic activityi

Transfers a segment of a (1->4)-alpha-D-glucan chain to a primary hydroxy group in a similar glucan chain.

Pathwayi

Sites

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Active sitei358 – 3581NucleophileBy similarity
Active sitei419 – 4191Proton donorBy similarity

GO - Molecular functioni

  1. 1,4-alpha-glucan branching enzyme activity Source: UniProtKB-EC
  2. cation binding Source: InterPro
  3. hydrolase activity, hydrolyzing O-glycosyl compounds Source: InterPro

GO - Biological processi

  1. glycogen biosynthetic process Source: UniProtKB-UniPathway
Complete GO annotation...

Keywords - Molecular functioni

Glycosyltransferase, Transferase

Keywords - Biological processi

Glycogen biosynthesis

Enzyme and pathway databases

UniPathwayiUPA00164.

Names & Taxonomyi

Protein namesi
Recommended name:
1,4-alpha-glucan-branching enzyme (EC:2.4.1.18)
Alternative name(s):
Glycogen-branching enzyme
Gene namesi
Name:GLC3
Ordered Locus Names:CAGL0M03377g
OrganismiCandida glabrata (strain ATCC 2001 / CBS 138 / JCM 3761 / NBRC 0622 / NRRL Y-65) (Yeast) (Torulopsis glabrata)
Taxonomic identifieri284593 [NCBI]
Taxonomic lineageiEukaryotaFungiDikaryaAscomycotaSaccharomycotinaSaccharomycetesSaccharomycetalesSaccharomycetaceaeNakaseomycesNakaseomyces/Candida clade
ProteomesiUP000002428: Chromosome M

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Chaini1 – 7067061,4-alpha-glucan-branching enzymePRO_0000188779Add
BLAST

Structurei

3D structure databases

ProteinModelPortaliQ6FJV0.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Phylogenomic databases

HOGENOMiHOG000175159.
InParanoidiQ6FJV0.
KOiK00700.
OMAiNEESHEM.
OrthoDBiEOG7647B5.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FJV0-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSLTKIPENV QGAVSIDPWL EPFADVLSER RYLADKWLYD IKHATPDGSE
60 70 80 90 100
QSLVDFARNA YKTYGLHANQ QTKEIVYREW APNAQRAFLV GEFNNWNEES
110 120 130 140 150
HEMKHKDEFG VFSITLAPLE NGDFAIPHDS KIKVMFVLPD GSKVYRIPAW
160 170 180 190 200
ITRATQPSKE TAQKYGPTYE GRFWNPPNSY QFKHQRPKFN LANDSIKIYE
210 220 230 240 250
AHIGISSPEP KVASYKEFTQ NVLPRIKHLG YDAIQLMAIM EHAYYASFGY
260 270 280 290 300
QVTNFFAISS RYGTPEDLKE LIDTAHSMGI LVLLDVIHSH ASKNSEDGLN
310 320 330 340 350
MFDGSDHQYF HSLTSGRGEH PLWDSRLFNY GSFEVQRFLL ANLAYYIDVY
360 370 380 390 400
QFDGFRFDGV TSMLYLHHGV GAGGAFSGDY NEYLSRDRSG VDHEALAYLM
410 420 430 440 450
LANDLVHDLL PESAVTIAED VSGYPTLCLP RTAGGGGFDY RLAMALPDMW
460 470 480 490 500
IKLLKTKQDD DWDMGHIVHT LTNRRHGEKV VAYCESHDQA LVGDKTLAFW
510 520 530 540 550
LMDAAMYTDM TVLKEPTLVI DRGIALHKMI RLITHSLGGE AYLNFEGNEF
560 570 580 590 600
GHPEWLDFPR VGNNDSYHYA RRQFNLVDDD LLRYRHLNEF DAAMQNCESK
610 620 630 640 650
HQWLNTPQAY VSLKHEVDKV IAFERNGHLF VFNFHPTQSF TDYRIGVDVA
660 670 680 690 700
GTYKIVLNTD RAEFGGHNRI DEAQEFFTTD LEWNNRRNFI QVYIPSRTAI

VLTRQM
Length:706
Mass (Da):81,044
Last modified:July 19, 2004 - v1
Checksum:i18872CAADBCD2A87
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380959 Genomic DNA. Translation: CAG62470.1.
RefSeqiXP_449494.1. XM_449494.1.

Genome annotation databases

GeneIDi2891502.
KEGGicgr:CAGL0M03377g.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR380959 Genomic DNA. Translation: CAG62470.1.
RefSeqiXP_449494.1. XM_449494.1.

3D structure databases

ProteinModelPortaliQ6FJV0.
ModBaseiSearch...
MobiDBiSearch...

Protocols and materials databases

Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi2891502.
KEGGicgr:CAGL0M03377g.

Phylogenomic databases

HOGENOMiHOG000175159.
InParanoidiQ6FJV0.
KOiK00700.
OMAiNEESHEM.
OrthoDBiEOG7647B5.

Enzyme and pathway databases

UniPathwayiUPA00164.

Family and domain databases

Gene3Di2.60.40.10. 1 hit.
2.60.40.1180. 1 hit.
3.20.20.80. 1 hit.
InterProiIPR006048. A-amylase_b_C.
IPR006407. GlgB.
IPR015902. Glyco_hydro_13.
IPR013780. Glyco_hydro_13_b.
IPR006047. Glyco_hydro_13_cat_dom.
IPR004193. Glyco_hydro_13_N.
IPR013781. Glyco_hydro_catalytic_dom.
IPR017853. Glycoside_hydrolase_SF.
IPR013783. Ig-like_fold.
IPR014756. Ig_E-set.
[Graphical view]
PANTHERiPTHR10357. PTHR10357. 1 hit.
PfamiPF00128. Alpha-amylase. 1 hit.
PF02806. Alpha-amylase_C. 1 hit.
PF02922. CBM_48. 1 hit.
[Graphical view]
PIRSFiPIRSF000463. GlgB. 1 hit.
SUPFAMiSSF51445. SSF51445. 2 hits.
SSF81296. SSF81296. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiGLGB_CANGA
AccessioniPrimary (citable) accession number: Q6FJV0
Entry historyi
Integrated into UniProtKB/Swiss-Prot: May 10, 2005
Last sequence update: July 19, 2004
Last modified: January 7, 2015
This is version 77 of the entry and version 1 of the sequence. [Complete history]
Entry statusiReviewed (UniProtKB/Swiss-Prot)
Annotation programFungal Protein Annotation Program

Miscellaneousi

Keywords - Technical termi

Complete proteome, Reference proteome

Documents

  1. Glycosyl hydrolases
    Classification of glycosyl hydrolase families and list of entries
  2. PATHWAY comments
    Index of metabolic and biosynthesis pathways
  3. SIMILARITY comments
    Index of protein domains and families

External Data

Dasty 3

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.