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Protein

Glutathione S-transferase kappa

Gene

LOC51064

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

Catalytic activityi

RX + glutathione = HX + R-S-glutathione.UniRule annotation

Sites

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Active sitei16NucleophileUniRule annotation1

GO - Molecular functioni

Keywordsi

Molecular functionTransferaseUniRule annotationImported

Names & Taxonomyi

Protein namesi
Recommended name:
Glutathione S-transferase kappaUniRule annotation (EC:2.5.1.18UniRule annotation)
Gene namesi
Name:LOC51064Imported
Synonyms:GSTK1Imported
ORF Names:hCG_20682Imported, tcag7.883Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000197448.13

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134948237

PTM / Processingi

Proteomic databases

PRIDEiQ6FII1

Expressioni

Gene expression databases

BgeeiENSG00000197448
ExpressionAtlasiQ6FII1 baseline and differential

Interactioni

Protein-protein interaction databases

IntActiQ6FII1, 2 interactors

Structurei

3D structure databases

SMRiQ6FII1
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini7 – 210DSBAInterPro annotationAdd BLAST204

Sequence similaritiesi

Belongs to the GST superfamily. Kappa family.UniRule annotation

Phylogenomic databases

HOVERGENiHBG051852
KOiK13299

Family and domain databases

InterProiView protein in InterPro
IPR001853 DSBA-like_thioredoxin_dom
IPR014440 HCCAis_GSTk
IPR036249 Thioredoxin-like_sf
PfamiView protein in Pfam
PF01323 DSBA, 1 hit
PIRSFiPIRSF006386 HCCAis_GSTk, 1 hit
SUPFAMiSSF52833 SSF52833, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FII1-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGPLPRTVEL FYDVLSPYSW LGFEILCRYQ NIWNINLQLR PSLITGIMKD
60 70 80 90 100
SGNKPPGLLP RKGLYMANDL KLLRHHLQIP IHFPKDFLSV MLEKGSLSAM
110 120 130 140 150
RFLTAVNLEH PEMLEKASRE LWMRVWSRNE DITEPQSILA AAEKAGMSAE
160 170 180 190 200
QAQGLLEKIA TPKVKNQLKE TTEAACRYGA FGLPITVAHV DGQTHMLFGS
210 220
DRMELLAHLL GEKWMGPIPP AVNARL
Length:226
Mass (Da):25,497
Last modified:May 10, 2005 - v1
Checksum:iD3FDAFD1533B58A4
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK289580 mRNA Translation: BAF82269.1
CR533445 mRNA Translation: CAG38476.1
CH236959 Genomic DNA Translation: EAL23783.1
CH471198 Genomic DNA Translation: EAW51880.1
RefSeqiNP_057001.1, NM_015917.2
UniGeneiHs.390667

Genome annotation databases

GeneIDi373156
KEGGihsa:373156

Similar proteinsi

Entry informationi

Entry nameiQ6FII1_HUMAN
AccessioniPrimary (citable) accession number: Q6FII1
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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