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Protein
Submitted name:

TOLLIP protein

Gene

TOLLIP

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at protein leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
TOLLIP proteinImported
Submitted name:
Toll interacting proteinImported
Submitted name:
Toll interacting protein, isoform CRA_aImported
Submitted name:
cDNA, FLJ96670, Homo sapiens toll interacting protein (TOLLIP), mRNAImported
Gene namesi
Name:TOLLIPImported
ORF Names:hCG_40380Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000078902.15

Subcellular locationi

Extracellular region or secreted Cytosol Plasma membrane Cytoskeleton Lysosome Endosome Peroxisome ER Golgi apparatus Nucleus Mitochondrion Manual annotation Automatic computational assertionGraphics by Christian Stolte; Source: COMPARTMENTS

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA134876213

PTM / Processingi

Proteomic databases

PRIDEiQ6FIE9

Expressioni

Gene expression databases

BgeeiENSG00000078902
ExpressionAtlasiQ6FIE9 baseline and differential

Interactioni

Binary interactionsi

Show more details

Protein-protein interaction databases

IntActiQ6FIE9, 7 interactors

Structurei

3D structure databases

SMRiQ6FIE9
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini229 – 272CUEInterPro annotationAdd BLAST44

Phylogenomic databases

eggNOGiENOG410IE45 Eukaryota
ENOG410XQPY LUCA
HOVERGENiHBG054213
KOiK05402
OMAiHVTIPES
OrthoDBiEOG091G0JE1

Family and domain databases

CDDicd04016 C2_Tollip, 1 hit
Gene3Di2.60.40.150, 1 hit
InterProiView protein in InterPro
IPR000008 C2_dom
IPR035892 C2_domain_sf
IPR003892 CUE
IPR037301 Tollip_C2
IPR009060 UBA-like_sf
PfamiView protein in Pfam
PF00168 C2, 1 hit
PF02845 CUE, 1 hit
SMARTiView protein in SMART
SM00239 C2, 1 hit
SM00546 CUE, 1 hit
SUPFAMiSSF46934 SSF46934, 1 hit
PROSITEiView protein in PROSITE
PS51140 CUE, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FIE9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MATTVSTQRG PVYIGELPQD FLRITPTQQQ RQVQLDAQAA QQLQYGGAVG
60 70 80 90 100
TVGRLNITVV QAKLAKNYGM TRMDPYCRLR LGYAVYETPT AHNGAKNPRW
110 120 130 140 150
NKVIHCTVPP GVDSFYLEIF DERAFSMDDR IAWTHITIPE SLRQGKVEDK
160 170 180 190 200
WYSLSGRQGD DKEGMINLVM SYALLPAAMV MPPQPVVLMP TVYQQGVGYV
210 220 230 240 250
PITGMPAVCS PGMVPVALPP AAVNAQPRCS EEDLKAIQDM FPNMDQEVIR
260 270
SVLEAQRGNK DAAINSLLQM GEEP
Length:274
Mass (Da):30,282
Last modified:May 10, 2005 - v1
Checksum:i386E0F284D3837DA
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AY730683 mRNA Translation: AAX22229.1
AK315592 mRNA Translation: BAG37964.1
CR533477 mRNA Translation: CAG38508.1
CH471158 Genomic DNA Translation: EAX02433.1
CH471158 Genomic DNA Translation: EAX02434.1
RefSeqiNP_061882.2, NM_019009.3
UniGeneiHs.368527

Genome annotation databases

GeneIDi54472
KEGGihsa:54472

Similar proteinsi

Entry informationi

Entry nameiQ6FIE9_HUMAN
AccessioniPrimary (citable) accession number: Q6FIE9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 107 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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