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Protein
Submitted name:

PACSIN2 protein

Gene

PACSIN2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

  1. actin cytoskeleton organization Source: InterPro
  2. caveola assembly Source: InterPro
  3. membrane tubulation Source: InterPro
Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
PACSIN2 proteinImported
Gene namesi
Name:PACSIN2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA32897.

PTM / Processingi

Proteomic databases

PRIDEiQ6FIA3.

Expressioni

Gene expression databases

ExpressionAtlasiQ6FIA3. baseline and differential.

Structurei

3D structure databases

ProteinModelPortaliQ6FIA3.
SMRiQ6FIA3. Positions 16-303, 388-443.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Contains FCH domain.SAAS annotation

Keywords - Domaini

SH3 domainSAAS annotation

Phylogenomic databases

HOGENOMiHOG000007245.
HOVERGENiHBG053486.

Family and domain databases

InterProiIPR001060. FCH_dom.
IPR028521. PACSIN2.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR10959:SF2. PTHR10959:SF2. 1 hit.
PfamiPF00611. FCH. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00055. FCH. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50133. FCH. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FIA3-1 [UniParc]FASTAAdd to Basket

« Hide

        10         20         30         40         50
MSVTYDDSVG VEVSSDSFWE VGNYKRTVKR IDDGHRLCSD LMNCLHERAR
60 70 80 90 100
IEKAYAQQLT EWARRWRQLV EKGPQYGTVE KAWMAFMSEA ERVSELHLEV
110 120 130 140 150
KASLMNDDFE KIKNWQKEAF HKQMMGGFKE TKEAEDGFRK AQKPWAKKLK
160 170 180 190 200
EVEAAKKAHH AACKEEKLAI SREANSKADP SLNPEQLKKL QDKIEKCKQD
210 220 230 240 250
VLKTKEKYEK SLKELDQGTP QYMENMEQVF EQCQQFEEKR LRFFREVLLE
260 270 280 290 300
VQKHLDLSNV AGYKAIYHDL EQSIRAADAV EDLRWFRANH GPGMAMNWPQ
310 320 330 340 350
FEEWSADLNR TLSRREKKKA TDGVTLTGIN QTGDQSLPSK PSSVSSYEKT
360 370 380 390 400
QSYPTDWSDD ESNNPFSSTD ANGDSNPFDD DATSGTEVRV RALYDYEGQE
410 420 430 440
HDELSFKAGD ELTKMEDEDE QGWCKGRLDN GQVGLYPANY VEAIQ
Length:445
Mass (Da):51,353
Last modified:May 10, 2005 - v1
Checksum:i1DA87A2D42B5D5F9
GO

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR533523 mRNA. Translation: CAG38554.1.
RefSeqiNP_001171900.1. NM_001184971.1.
XP_005261376.1. XM_005261319.2.
UniGeneiHs.162877.

Genome annotation databases

GeneIDi11252.
KEGGihsa:11252.
UCSCiuc003bdf.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
CR533523 mRNA. Translation: CAG38554.1.
RefSeqiNP_001171900.1. NM_001184971.1.
XP_005261376.1. XM_005261319.2.
UniGeneiHs.162877.

3D structure databases

ProteinModelPortaliQ6FIA3.
SMRiQ6FIA3. Positions 16-303, 388-443.
ModBaseiSearch...
MobiDBiSearch...

Proteomic databases

PRIDEiQ6FIA3.

Protocols and materials databases

DNASUi11252.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi11252.
KEGGihsa:11252.
UCSCiuc003bdf.4. human.

Organism-specific databases

CTDi11252.
PharmGKBiPA32897.

Phylogenomic databases

HOGENOMiHOG000007245.
HOVERGENiHBG053486.

Miscellaneous databases

ChiTaRSiPACSIN2. human.
GenomeRNAii11252.
NextBioi42818.

Gene expression databases

ExpressionAtlasiQ6FIA3. baseline and differential.

Family and domain databases

InterProiIPR001060. FCH_dom.
IPR028521. PACSIN2.
IPR001452. SH3_domain.
[Graphical view]
PANTHERiPTHR10959:SF2. PTHR10959:SF2. 1 hit.
PfamiPF00611. FCH. 1 hit.
PF14604. SH3_9. 1 hit.
[Graphical view]
PRINTSiPR00452. SH3DOMAIN.
SMARTiSM00055. FCH. 1 hit.
SM00326. SH3. 1 hit.
[Graphical view]
SUPFAMiSSF50044. SSF50044. 1 hit.
PROSITEiPS50133. FCH. 1 hit.
PS50002. SH3. 1 hit.
[Graphical view]
ProtoNetiSearch...

Publicationsi

  1. "Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
    Ebert L., Schick M., Neubert P., Schatten R., Henze S., Korn B.
    Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
    Cited for: NUCLEOTIDE SEQUENCE.

Entry informationi

Entry nameiQ6FIA3_HUMAN
AccessioniPrimary (citable) accession number: Q6FIA3
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: October 29, 2014
This is version 69 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into Uniref entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.