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Protein
Submitted name:

G protein-coupled receptor kinase-interactor 2 isoform 4

Gene

GIT2

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 1 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

Keywordsi

Molecular functionKinaseImported, ReceptorImported, Transferase
LigandMetal-binding, Zinc

Names & Taxonomyi

Protein namesi
Submitted name:
G protein-coupled receptor kinase-interactor 2 isoform 4Imported
Submitted name:
G protein-coupled receptor kinase-interactor 2 isoform 4 variantImported
Submitted name:
GIT2 proteinImported
Gene namesi
Name:GIT2Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA28684.

PTM / Processingi

Proteomic databases

MaxQBiQ6FI58.

Expressioni

Gene expression databases

BgeeiENSG00000139436.
ExpressionAtlasiQ6FI58. baseline and differential.

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini132 – 221ANK_REP_REGIONInterPro annotationAdd BLAST90
Repeati166 – 198ANKPROSITE-ProRule annotationAdd BLAST33

Coiled coil

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Coiled coili437 – 464Sequence analysisAdd BLAST28

Keywords - Domaini

ANK repeatPROSITE-ProRule annotation, Coiled coilSequence analysis, Zinc-fingerPROSITE-ProRule annotation

Phylogenomic databases

eggNOGiKOG0818. Eukaryota.
ENOG410XR8U. LUCA.
HOVERGENiHBG012506.

Family and domain databases

CDDicd00204. ANK. 1 hit.
Gene3Di1.25.40.20. 1 hit.
InterProiView protein in InterPro
IPR002110. Ankyrin_rpt.
IPR020683. Ankyrin_rpt-contain_dom.
IPR001164. ArfGAP.
IPR032352. GIT1/2_CC.
IPR013724. GIT_SHD.
PfamiView protein in Pfam
PF12796. Ank_2. 1 hit.
PF01412. ArfGap. 1 hit.
PF16559. GIT_CC. 1 hit.
PF08518. GIT_SHD. 2 hits.
PRINTSiPR00405. REVINTRACTNG.
SMARTiView protein in SMART
SM00248. ANK. 3 hits.
SM00105. ArfGap. 1 hit.
SM00555. GIT. 2 hits.
SUPFAMiSSF48403. SSF48403. 1 hit.
PROSITEiView protein in PROSITE
PS50297. ANK_REP_REGION. 1 hit.
PS50088. ANK_REPEAT. 1 hit.
PS50115. ARFGAP. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FI58-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MSKRLRSSEV CADCSGPDPS WASVNRGTFL CDECCSVHRS LGRHISQVRH
60 70 80 90 100
LKHTPWPPTL LQMVETLYNN GANSIWEHSL LDPASIMSGR RKANPQDKVH
110 120 130 140 150
PNKAEFIRAK YQMLAFVHRL PCRDDDSVTA KDLSKQLHSS VRTGNLETCL
160 170 180 190 200
RLLSLGAQAN FFHPEKGNTP LHVASKAGQI LQAELLAVYG ADPGTQDSSG
210 220 230 240 250
KTPVDYARQG GHHELAERLV EIQYELTDRL AFYLCGRKPD HKNGQHFIIP
260 270 280 290 300
QMADSSLDLS ELAKAAKKKL QSLSNHLFEE LAMDVYDEVD RRETDAVWLA
310 320 330 340 350
TQNHSALVTE TTVVPFLPVN PEYSSTRNQG RQKLARFNAH EFATLVIDIL
360 370 380 390 400
SDAKRRQQGS SLSGSKDNVE LILKTINNQH SVESQDNDQP DYDSVASDED
410 420 430 440 450
TDLETTASKT NRQKSLDSDL SDGPVTVQEF MEVKNALVAS EAKIQQLMKV
460 470
NNNLSDELRI MQKKLLGKDA N
Length:471
Mass (Da):52,577
Last modified:May 10, 2005 - v1
Checksum:i4C82BB94EA3634DA
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei471Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK222736 mRNA. Translation: BAD96456.1.
AB451428 mRNA. Translation: BAG70242.1.
CR533568 mRNA. Translation: CAG38599.1.
RefSeqiNP_001317083.1. NM_001330154.1.
NP_631940.2. NM_139201.2.
UniGeneiHs.434996.

Genome annotation databases

GeneIDi9815.
UCSCiuc001tpw.4. human.

Similar proteinsi

Entry informationi

Entry nameiQ6FI58_HUMAN
AccessioniPrimary (citable) accession number: Q6FI58
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: August 30, 2017
This is version 112 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.