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Protein
Submitted name:

MAP2K3 protein

Gene

MAP2K3

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: -Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Keywordsi

Molecular functionKinase, Serine/threonine-protein kinaseUniRule annotation, Transferase
LigandATP-bindingUniRule annotation, Nucleotide-binding

Names & Taxonomyi

Protein namesi
Submitted name:
MAP2K3 proteinImported
Submitted name:
Mitogen-activated protein kinase kinase 3 isoform BImported
Submitted name:
cDNA, FLJ96569, Homo sapiens mitogen-activated protein kinase kinase 3 (MAP2K3),transcript variant B, mRNAImported
Gene namesi
Name:MAP2K3Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Organism-specific databases

EuPathDBiHostDB:ENSG00000034152.18

Subcellular locationi

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA30588

PTM / Processingi

Proteomic databases

MaxQBiQ6FI23
PRIDEiQ6FI23

Expressioni

Gene expression databases

BgeeiENSG00000034152
ExpressionAtlasiQ6FI23 baseline and differential

Interactioni

GO - Molecular functioni

Chemistry databases

BindingDBiQ6FI23

Structurei

3D structure databases

SMRiQ6FI23
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini64 – 325Protein kinaseInterPro annotationAdd BLAST262

Sequence similaritiesi

Belongs to the protein kinase superfamily.UniRule annotation

Phylogenomic databases

eggNOGiKOG0984 Eukaryota
ENOG410XT3F LUCA
HOVERGENiHBG108518
KOiK04432
OMAiACVTIGD
OrthoDBiEOG091G0A9H

Family and domain databases

InterProiView protein in InterPro
IPR011009 Kinase-like_dom_sf
IPR000719 Prot_kinase_dom
IPR017441 Protein_kinase_ATP_BS
IPR008271 Ser/Thr_kinase_AS
PfamiView protein in Pfam
PF00069 Pkinase, 1 hit
SMARTiView protein in SMART
SM00220 S_TKc, 1 hit
SUPFAMiSSF56112 SSF56112, 1 hit
PROSITEiView protein in PROSITE
PS00107 PROTEIN_KINASE_ATP, 1 hit
PS50011 PROTEIN_KINASE_DOM, 1 hit
PS00108 PROTEIN_KINASE_ST, 1 hit

Sequencei

Sequence statusi: Complete.

Q6FI23-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MESPASSQPA SMPQSKGKSK RKKDLRISCM SKPPAPNPTP PRNLDSRTFI
60 70 80 90 100
TIGDRNFEVE ADDLVTISEL GRGAYGVVEK VRHAQSGTIM AVKRIRATVN
110 120 130 140 150
SQEQKRLLMD LDINMRTVDC FYTVTFYGAL FREGDVWICM ELMDTSLDKF
160 170 180 190 200
YRKVLDKNMT IPEDILGEIA VSIVRALEHL HSKLSVIHRD VKPSNVLINK
210 220 230 240 250
EGHVKMCDFG ISGYLVDSVA KTMDAGCKPY MAPERINPEL NQKGYNVKSD
260 270 280 290 300
VWSLGITMIE MAILRFPYES WGTPFQQLKQ VVEEPSPQLP ADRFSPEFVD
310 320 330 340
FTAQCLRKNP AERMSYLELM EHPFFTLHKT KKTDIAAFVK EILGEDS
Length:347
Mass (Da):39,318
Last modified:May 10, 2005 - v1
Checksum:iA80BA4FDFF8F75A2
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei347Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK315505 mRNA Translation: BAG37889.1
AB451226 mRNA Translation: BAG70040.1
AB451349 mRNA Translation: BAG70163.1
CR536514 mRNA Translation: CAG38752.1
RefSeqiNP_659731.1, NM_145109.2
UniGeneiHs.514012

Genome annotation databases

GeneIDi5606
KEGGihsa:5606
UCSCiuc002gys.4 human

Similar proteinsi

Entry informationi

Entry nameiQ6FI23_HUMAN
AccessioniPrimary (citable) accession number: Q6FI23
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: May 23, 2018
This is version 116 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

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