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Protein
Submitted name:

CCND1 protein

Gene

CCND1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 4 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Molecular functioni

GO - Biological processi

Complete GO annotation...

Keywords - Molecular functioni

CyclinUniRule annotationSAAS annotation

Names & Taxonomyi

Protein namesi
Submitted name:
CCND1 proteinImported
Submitted name:
Cyclin D1 (PRAD1: parathyroid adenomatosis 1)Imported
Submitted name:
Cyclin D1, isoform CRA_cImported
Submitted name:
cDNA, FLJ93625, Homo sapiens cyclin D1 (PRAD1: parathyroid adenomatosis 1) (CCND1),mRNAImported
Gene namesi
Name:CCND1Imported
ORF Names:hCG_2016647Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA75.

PTM / Processingi

Proteomic databases

MaxQBiQ6FI00.

Expressioni

Gene expression databases

BgeeiENSG00000110092.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000227507.

Structurei

3D structure databases

SMRiQ6FI00. Positions 22-267.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini57 – 8832Cyclin N-terminalInterPro annotationAdd
BLAST

Sequence similaritiesi

Belongs to the cyclin family.UniRule annotationSAAS annotation

Phylogenomic databases

eggNOGiKOG0656. Eukaryota.
ENOG410XRKC. LUCA.
HOVERGENiHBG050837.
KOiK04503.
OMAiMKETVPL.
OrthoDBiEOG091G0URX.
PhylomeDBiQ6FI00.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiIPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
SM01332. Cyclin_C. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
PROSITEiPS00292. CYCLINS. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FI00-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MEHQLLCCEV ETIRRAYPDA NLLNDRVLRA MLKAEETCAP SVSYFKCVQK
60 70 80 90 100
EVLPSMRKIV ATWMLEVCEE QKCEEEVFPL AMNYLDRFLS LEPVKKSRLQ
110 120 130 140 150
LLGATCMFVA SKMKETIPLT AEKLCIYTDN SIRPEELLQM ELLLVNKLKW
160 170 180 190 200
NLAAMTPHDF IEHFLSKMPE AEENKQIIRK HAQTFVALCA TDVKFISNPP
210 220 230 240 250
SMVAAGSVVA AVQGLNLRSP NNFLSYYRLT RFLSRVIKCD PDCLRACQEQ
260 270 280 290
IEALLESSLR QAQQNMDPKA AEEEEEEEEE VDLACTPTDV RDVDI
Length:295
Mass (Da):33,729
Last modified:May 10, 2005 - v1
Checksum:i3CC00C9905F58D3A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei295 – 2951Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019844 mRNA. Translation: AAV38647.1.
AK313136 mRNA. Translation: BAG35955.1.
CR536538 mRNA. Translation: CAG38775.1.
CR542099 mRNA. Translation: CAG46896.1.
CH471076 Genomic DNA. Translation: EAW74748.1.
RefSeqiNP_444284.1. NM_053056.2.
UniGeneiHs.523852.

Genome annotation databases

GeneIDi595.
KEGGihsa:595.
UCSCiuc001opa.4. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BT019844 mRNA. Translation: AAV38647.1.
AK313136 mRNA. Translation: BAG35955.1.
CR536538 mRNA. Translation: CAG38775.1.
CR542099 mRNA. Translation: CAG46896.1.
CH471076 Genomic DNA. Translation: EAW74748.1.
RefSeqiNP_444284.1. NM_053056.2.
UniGeneiHs.523852.

3D structure databases

SMRiQ6FI00. Positions 22-267.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000227507.

Proteomic databases

MaxQBiQ6FI00.

Protocols and materials databases

DNASUi595.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi595.
KEGGihsa:595.
UCSCiuc001opa.4. human.

Organism-specific databases

CTDi595.
PharmGKBiPA75.

Phylogenomic databases

eggNOGiKOG0656. Eukaryota.
ENOG410XRKC. LUCA.
HOVERGENiHBG050837.
KOiK04503.
OMAiMKETVPL.
OrthoDBiEOG091G0URX.
PhylomeDBiQ6FI00.

Miscellaneous databases

ChiTaRSiCCND1. human.
GenomeRNAii595.

Gene expression databases

BgeeiENSG00000110092.

Family and domain databases

Gene3Di1.10.472.10. 2 hits.
InterProiIPR013763. Cyclin-like.
IPR004367. Cyclin_C-dom.
IPR006671. Cyclin_N.
[Graphical view]
PfamiPF02984. Cyclin_C. 1 hit.
PF00134. Cyclin_N. 1 hit.
[Graphical view]
SMARTiSM00385. CYCLIN. 1 hit.
SM01332. Cyclin_C. 1 hit.
[Graphical view]
SUPFAMiSSF47954. SSF47954. 2 hits.
PROSITEiPS00292. CYCLINS. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FI00_HUMAN
AccessioniPrimary (citable) accession number: Q6FI00
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 102 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.