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Protein
Submitted name:

CD59 antigen, complement regulatory protein, isoform CRA_b

Gene

CD59

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Submitted name:
CD59 antigen, complement regulatory protein, isoform CRA_bImported
Submitted name:
CD59 proteinImported
Submitted name:
cDNA, FLJ92039, Homo sapiens CD59 antigen p18-20 (antigen identified by monoclonalantibodies 16.3A5, EJ16, EJ30, EL32 and G344) (CD59), mRNAImported
Gene namesi
Name:CD59Imported
ORF Names:hCG_2033390Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Complete GO annotation...

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26228.

PTM / Processingi

Molecule processing

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Signal peptidei1 – 2525Sequence analysisAdd
BLAST
Chaini26 – 128103Sequence analysisPRO_5007708192Add
BLAST

Proteomic databases

MaxQBiQ6FHM9.

Expressioni

Gene expression databases

BgeeiENSG00000085063.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000340210.

Structurei

3D structure databases

SMRiQ6FHM9. Positions 26-102.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Domaini26 – 10883UPAR/Ly6InterPro annotationAdd
BLAST

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J39P. Eukaryota.
ENOG410ZEQP. LUCA.
HOVERGENiHBG005284.
KOiK04008.
OMAiNKAAFSI.
PhylomeDBiQ6FHM9.

Family and domain databases

InterProiIPR018363. CD59_antigen_CS.
IPR027101. CD59_glyco.
IPR016054. LY6_UPA_recep-like.
[Graphical view]
PANTHERiPTHR10036:SF9. PTHR10036:SF9. 1 hit.
PfamiPF00021. UPAR_LY6. 1 hit.
[Graphical view]
SMARTiSM00134. LU. 1 hit.
[Graphical view]
PROSITEiPS00983. LY6_UPAR. 1 hit.
[Graphical view]

Sequencei

Sequence statusi: Complete.

Q6FHM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIQGGSVLF GLLLVLAVFC HSGHSLQCYN CPNPTADCKT AVNCSSDFDA
60 70 80 90 100
CLITKAGLQV YNKCWKFEHC NFNDVTTRLR ENELTYYCCK KDLCNFNEQL
110 120
ENGGTSLSEK TVLLLVTPFL AAAWSLHP
Length:128
Mass (Da):14,177
Last modified:May 10, 2005 - v1
Checksum:i2F0D29CBE3C28505
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei128 – 1281Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311778 mRNA. Translation: BAG34721.1.
CR407661 mRNA. Translation: CAG28589.1.
CR541722 mRNA. Translation: CAG46523.1.
CH471064 Genomic DNA. Translation: EAW68193.1.
RefSeqiNP_000602.1. NM_000611.5.
NP_001120695.1. NM_001127223.1.
NP_001120697.1. NM_001127225.1.
NP_001120698.1. NM_001127226.1.
NP_001120699.1. NM_001127227.1.
NP_976074.1. NM_203329.2.
NP_976075.1. NM_203330.2.
NP_976076.1. NM_203331.2.
UniGeneiHs.278573.
Hs.709466.
Hs.710641.

Genome annotation databases

GeneIDi966.
KEGGihsa:966.
UCSCiuc001mus.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311778 mRNA. Translation: BAG34721.1.
CR407661 mRNA. Translation: CAG28589.1.
CR541722 mRNA. Translation: CAG46523.1.
CH471064 Genomic DNA. Translation: EAW68193.1.
RefSeqiNP_000602.1. NM_000611.5.
NP_001120695.1. NM_001127223.1.
NP_001120697.1. NM_001127225.1.
NP_001120698.1. NM_001127226.1.
NP_001120699.1. NM_001127227.1.
NP_976074.1. NM_203329.2.
NP_976075.1. NM_203330.2.
NP_976076.1. NM_203331.2.
UniGeneiHs.278573.
Hs.709466.
Hs.710641.

3D structure databases

SMRiQ6FHM9. Positions 26-102.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000340210.

Proteomic databases

MaxQBiQ6FHM9.

Protocols and materials databases

DNASUi966.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi966.
KEGGihsa:966.
UCSCiuc001mus.5. human.

Organism-specific databases

CTDi966.
PharmGKBiPA26228.

Phylogenomic databases

eggNOGiENOG410J39P. Eukaryota.
ENOG410ZEQP. LUCA.
HOVERGENiHBG005284.
KOiK04008.
OMAiNKAAFSI.
PhylomeDBiQ6FHM9.

Miscellaneous databases

ChiTaRSiCD59. human.
GenomeRNAii966.

Gene expression databases

BgeeiENSG00000085063.

Family and domain databases

InterProiIPR018363. CD59_antigen_CS.
IPR027101. CD59_glyco.
IPR016054. LY6_UPA_recep-like.
[Graphical view]
PANTHERiPTHR10036:SF9. PTHR10036:SF9. 1 hit.
PfamiPF00021. UPAR_LY6. 1 hit.
[Graphical view]
SMARTiSM00134. LU. 1 hit.
[Graphical view]
PROSITEiPS00983. LY6_UPAR. 1 hit.
[Graphical view]
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FHM9_HUMAN
AccessioniPrimary (citable) accession number: Q6FHM9
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: September 7, 2016
This is version 98 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.