Skip Header

You are using a version of browser that may not display all the features of this website. Please consider upgrading your browser.
Protein
Submitted name:

CD59 antigen, complement regulatory protein, isoform CRA_b

Gene

CD59

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Names & Taxonomyi

Protein namesi
Submitted name:
CD59 antigen, complement regulatory protein, isoform CRA_bImported
Submitted name:
CD59 proteinImported
Submitted name:
cDNA, FLJ92039, Homo sapiens CD59 antigen p18-20 (antigen identified by monoclonalantibodies 16.3A5, EJ16, EJ30, EL32 and G344) (CD59), mRNAImported
Gene namesi
Name:CD59Imported
ORF Names:hCG_2033390Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA26228.

PTM / Processingi

Molecule processing

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Signal peptidei1 – 25Sequence analysisAdd BLAST25
ChainiPRO_500878240026 – 128Sequence analysisAdd BLAST103

Proteomic databases

MaxQBiQ6FHM9.

Expressioni

Gene expression databases

BgeeiENSG00000085063.
ExpressionAtlasiQ6FHM9. baseline and differential.

Interactioni

Protein-protein interaction databases

STRINGi9606.ENSP00000340210.

Structurei

3D structure databases

ProteinModelPortaliQ6FHM9.
SMRiQ6FHM9.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Domains and Repeats

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Domaini26 – 108UPAR/Ly6InterPro annotationAdd BLAST83

Keywords - Domaini

SignalSequence analysis

Phylogenomic databases

eggNOGiENOG410J39P. Eukaryota.
ENOG410ZEQP. LUCA.
HOVERGENiHBG005284.
KOiK04008.
OMAiNKAAFSI.
PhylomeDBiQ6FHM9.

Family and domain databases

InterProiView protein in InterPro
IPR018363. CD59_antigen_CS.
IPR027101. CD59_glyco.
IPR016054. LY6_UPA_recep-like.
PANTHERiPTHR10036:SF13. PTHR10036:SF13. 1 hit.
PfamiView protein in Pfam
PF00021. UPAR_LY6. 1 hit.
SMARTiView protein in SMART
SM00134. LU. 1 hit.
PROSITEiView protein in PROSITE
PS00983. LY6_UPAR. 1 hit.

Sequencei

Sequence statusi: Complete.

Q6FHM9-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MGIQGGSVLF GLLLVLAVFC HSGHSLQCYN CPNPTADCKT AVNCSSDFDA
60 70 80 90 100
CLITKAGLQV YNKCWKFEHC NFNDVTTRLR ENELTYYCCK KDLCNFNEQL
110 120
ENGGTSLSEK TVLLLVTPFL AAAWSLHP
Length:128
Mass (Da):14,177
Last modified:May 10, 2005 - v1
Checksum:i2F0D29CBE3C28505
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei128Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311778 mRNA. Translation: BAG34721.1.
CR407661 mRNA. Translation: CAG28589.1.
CR541722 mRNA. Translation: CAG46523.1.
CH471064 Genomic DNA. Translation: EAW68193.1.
RefSeqiNP_000602.1. NM_000611.5.
NP_001120695.1. NM_001127223.1.
NP_001120697.1. NM_001127225.1.
NP_001120698.1. NM_001127226.1.
NP_001120699.1. NM_001127227.1.
NP_976074.1. NM_203329.2.
NP_976075.1. NM_203330.2.
NP_976076.1. NM_203331.2.
UniGeneiHs.278573.
Hs.709466.
Hs.710641.

Genome annotation databases

GeneIDi966.
KEGGihsa:966.
UCSCiuc001mus.5. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK311778 mRNA. Translation: BAG34721.1.
CR407661 mRNA. Translation: CAG28589.1.
CR541722 mRNA. Translation: CAG46523.1.
CH471064 Genomic DNA. Translation: EAW68193.1.
RefSeqiNP_000602.1. NM_000611.5.
NP_001120695.1. NM_001127223.1.
NP_001120697.1. NM_001127225.1.
NP_001120698.1. NM_001127226.1.
NP_001120699.1. NM_001127227.1.
NP_976074.1. NM_203329.2.
NP_976075.1. NM_203330.2.
NP_976076.1. NM_203331.2.
UniGeneiHs.278573.
Hs.709466.
Hs.710641.

3D structure databases

ProteinModelPortaliQ6FHM9.
SMRiQ6FHM9.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000340210.

Proteomic databases

MaxQBiQ6FHM9.

Protocols and materials databases

DNASUi966.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi966.
KEGGihsa:966.
UCSCiuc001mus.5. human.

Organism-specific databases

CTDi966.
PharmGKBiPA26228.

Phylogenomic databases

eggNOGiENOG410J39P. Eukaryota.
ENOG410ZEQP. LUCA.
HOVERGENiHBG005284.
KOiK04008.
OMAiNKAAFSI.
PhylomeDBiQ6FHM9.

Miscellaneous databases

ChiTaRSiCD59. human.
GenomeRNAii966.

Gene expression databases

BgeeiENSG00000085063.
ExpressionAtlasiQ6FHM9. baseline and differential.

Family and domain databases

InterProiView protein in InterPro
IPR018363. CD59_antigen_CS.
IPR027101. CD59_glyco.
IPR016054. LY6_UPA_recep-like.
PANTHERiPTHR10036:SF13. PTHR10036:SF13. 1 hit.
PfamiView protein in Pfam
PF00021. UPAR_LY6. 1 hit.
SMARTiView protein in SMART
SM00134. LU. 1 hit.
PROSITEiView protein in PROSITE
PS00983. LY6_UPAR. 1 hit.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FHM9_HUMAN
AccessioniPrimary (citable) accession number: Q6FHM9
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: April 12, 2017
This is version 104 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.