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Unreviewed, UniProtKB/TrEMBL Q6FHM7 (Q6FHM7_HUMAN)

Last modified January 19, 2010. Version 31. Feed History...

Clusters with 100%, 90%, 50% identity | Third-party data | Customize display text xml rdf/xml gff fasta
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information

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Names and origin

Protein namesSubmitted name:
    JUN protein EMBL CAG46525.1
Gene names
Name: JUN EMBL CAG46525.1
OrganismHomo sapiens (Human) EMBL CAG46525.1
Taxonomic identifier9606 [NCBI]
Taxonomic lineageEukaryota › Metazoa › Chordata › Craniata › Vertebrata › Euteleostomi › Mammalia › Eutheria › Euarchontoglires › Primates › Haplorrhini › Catarrhini › Hominidae › Homo

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Protein attributes

Sequence length331 AA.
Sequence statusComplete.
Protein existenceEvidence at transcript level.

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General annotation (Comments)

Sequence similarities

Belongs to the bZIP family.

Contains 1 bZIP domain.

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Ontologies

Keywords
   Biological processTranscription
Transcription regulation Spearmint SPM011616
   Cellular componentNucleus RuleBase RU000470V2
   LigandDNA-binding RuleBase RU000470V2 Spearmint SPM008917
Gene Ontology (GO)
   Biological processaging

Inferred from electronic annotation. Source: Compara

angiogenesis

Inferred from electronic annotation. Source: Compara

cellular response to potassium ion starvation

Inferred from electronic annotation. Source: Compara

circadian rhythm

Inferred from electronic annotation. Source: Compara

leading edge cell differentiation

Inferred from electronic annotation. Source: Compara

learning

Inferred from electronic annotation. Source: Compara

membrane depolarization

Inferred from electronic annotation. Source: Compara

negative regulation of cell proliferation

Inferred from electronic annotation. Source: Compara

negative regulation of protein amino acid autophosphorylation

Inferred from electronic annotation. Source: Compara

positive regulation of DNA replication

Inferred from electronic annotation. Source: Compara

positive regulation of monocyte differentiation

Inferred from electronic annotation. Source: Compara

positive regulation of neuron apoptosis

Inferred from electronic annotation. Source: Compara

positive regulation of smooth muscle cell proliferation

Inferred from electronic annotation. Source: Compara

positive regulation of transcription from RNA polymerase II promoter

Inferred from electronic annotation. Source: Compara

regulation of cell cycle

Inferred from electronic annotation. Source: Compara

release of cytochrome c from mitochondria

Inferred from electronic annotation. Source: Compara

response to cAMP

Inferred from electronic annotation. Source: Compara

response to cytokine stimulus

Inferred from electronic annotation. Source: Compara

response to drug

Inferred from electronic annotation. Source: Compara

response to hydrogen peroxide

Inferred from electronic annotation. Source: Compara

response to lipopolysaccharide

Inferred from electronic annotation. Source: Compara

response to mechanical stimulus

Inferred from electronic annotation. Source: Compara

response to organic cyclic substance

Inferred from electronic annotation. Source: Compara

transcription

Inferred from electronic annotation. Source: UniProtKB-KW

   Cellular componentcytosol

Inferred from electronic annotation. Source: Compara

nuclear chromatin

Inferred from electronic annotation. Source: Compara

transcription factor complex

Inferred from electronic annotation. Source: Compara

   Molecular functionRNA polymerase II transcription factor activity

Inferred from electronic annotation. Source: Compara

double-stranded DNA binding

Inferred from electronic annotation. Source: Compara

protein dimerization activity

Inferred from electronic annotation. Source: InterPro

sequence-specific DNA binding

Inferred from electronic annotation. Source: InterPro

transcription factor activity

Inferred from electronic annotation. Source: InterPro

Complete GO annotation...

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Sequences

Sequence LengthMass (Da)Tools
Q6FHM7-1 [UniParc].

Last modified July 19, 2004. Version 1.
Checksum: 9CE7E228C933388C

FASTA33135,692
        10         20         30         40         50         60 
MTAKMETTFY DDALNASFLP SESGPYGYSN PKILKQSMTL NLADPVGSLK PHLRAKNSDL 

        70         80         90        100        110        120 
LTSPDVGLLK LASPELERLI IQSSNGHITT TPTPTQFLCP KNVTDEQEGF AEGFVRALAE 

       130        140        150        160        170        180 
LHSQNTLPSV TSAAQPVNGA GMVAPAVASV SGGSGSGGFS ASLHSEPPVY ANLSNFNPGA 

       190        200        210        220        230        240 
LSSGGGAPSY GAAGLAFPAQ PQQQQQPPHH LPQQMPVQHP RLQALKEEPQ TVPEMPGETP 

       250        260        270        280        290        300 
PLSPIDMESQ ERIKAERKRM RNRIAASKCR KRKLERIARL EEKVKTLKAQ NSELASTANM 

       310        320        330 
LREQVAQLKQ KVMNHVNSGC QLMLTQQLQT F

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References

[1]"Cloning of human full open reading frames in Gateway(TM) system entry vector (pDONR201)."
Halleck A., Ebert L., Mkoundinya M., Schick M., Eisenstein S., Neubert P., Kstrang K., Schatten R., Shen B., Henze S., Mar W., Korn B., Zuo D., Hu Y., LaBaer J.
Submitted (JUN-2004) to the EMBL/GenBank/DDBJ databases
Cited for: NUCLEOTIDE SEQUENCE.
+Additional computationally mapped references.

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Cross-references

Sequence databases

EMBL
GenBank
DDBJ		CR541724 mRNA. Translation: CAG46525.1.
IPIIPI00008965.

3D structure databases

SMRQ6FHM7. Positions 257-308.
ModBaseSearch...

Protein-protein interaction databases

STRINGQ6FHM7.

Genome annotation databases

EnsemblENST00000371222; ENSP00000360266; ENSG00000177606; Homo sapiens. [Genome view]

Organism-specific databases

HGNCHGNC:6204. JUN.
GenAtlasSearch...

Phylogenomic databases

HOVERGENQ6FHM7.

Gene expression databases

ArrayExpressQ6FHM7.
BgeeQ6FHM7.

Family and domain databases

InterProIPR011616. bZIP_1.
IPR015558. C_Jun.
IPR008917. Euk_TF_DNA_bd.
IPR005643. JNK.
IPR002112. Leuzip_Jun.
IPR004827. TF_bZIP.
[Graphical view]
PANTHERPTHR11462:SF8. C_Jun. 1 hit.
PfamPF00170. bZIP_1. 1 hit.
PF03957. Jun. 1 hit.
[Graphical view]
PRINTSPR00043. LEUZIPPRJUN.
SMARTSM00338. BRLZ. 1 hit.
[Graphical view]
PROSITEPS50217. BZIP. 1 hit.
PS00036. BZIP_BASIC. 1 hit.
[Graphical view]
ProtoNetSearch...

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Entry information

Entry nameQ6FHM7_HUMAN
AccessionPrimary (citable) accession number: Q6FHM7
Entry history
Integrated into UniProtKB/TrEMBL: July 19, 2004
Last sequence update: July 19, 2004
Last modified: January 19, 2010
This is version 31 of the entry and version 1 of the sequence. [Complete history]
Entry statusUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.
Names and origin · Protein attributes · General annotation (Comments) · Ontologies · Sequences · References · Cross-references · Entry information