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Protein
Submitted name:

KCNE1 protein

Gene

KCNE1

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at protein leveli

Functioni

GO - Molecular functioni

GO - Biological processi

  • cellular response to cAMP Source: BHF-UCL
  • potassium ion transmembrane transport Source: BHF-UCL
Complete GO annotation...

Protein family/group databases

TCDBi8.A.10.1.2. the slow voltage-gated k+) channel accessory protein (mink) family.

Names & Taxonomyi

Protein namesi
Submitted name:
KCNE1 proteinImported
Submitted name:
Potassium voltage-gated channel Isk-related family member 1Imported
Submitted name:
Potassium voltage-gated channel, Isk-related family, member 1Imported
Submitted name:
cDNA, FLJ94103, Homo sapiens potassium voltage-gated channel, Isk-related family,member 1 (KCNE1), mRNAImported
Gene namesi
Name:KCNE1Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

Topology

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Transmembranei44 – 6623HelicalSequence analysisAdd
BLAST

GO - Cellular componenti

  • voltage-gated potassium channel complex Source: BHF-UCL
Complete GO annotation...

Keywords - Cellular componenti

Membrane

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA211.

Interactioni

Binary interactionsi

WithEntry#Exp.IntActNotes
TPM3Q5VU623EBI-10215868,EBI-10184033
UBASH3AP570753EBI-10215868,EBI-2105393

Protein-protein interaction databases

STRINGi9606.ENSP00000337255.

Family & Domainsi

Keywords - Domaini

Transmembrane, Transmembrane helixSequence analysis

Phylogenomic databases

eggNOGiENOG410IY71. Eukaryota.
ENOG410Y1SF. LUCA.
HOVERGENiHBG052226.
KOiK04894.

Family and domain databases

InterProiIPR000369. K_chnl_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view]
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.

Sequencei

Sequence statusi: Fragment.

Q6FHJ6-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MILSNTTAVT PFLTKLWQET VQQGGNMSGL ARRSPRSGDG KLEALYVLMV
60 70 80 90 100
LGFFGFFTLG IMLSYIRSKK LEHSNDPFNV YIESDAWQEK DKAYVQARVL
110 120
ESYRSCYVVE NHLAIEQPNT HLPETKPSP
Length:129
Mass (Da):14,645
Last modified:May 10, 2005 - v1
Checksum:i4843171C7DC1A92A
GO

Experimental Info

Feature keyPosition(s)LengthDescriptionGraphical viewFeature identifierActions
Non-terminal residuei129 – 1291Imported

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046224 mRNA. Translation: AAH46224.1.
EF514883 mRNA. Translation: ABS84251.1.
EF514884 Genomic DNA. Translation: ABS84252.1.
AK313543 mRNA. Translation: BAG36319.1.
CR541756 mRNA. Translation: CAG46556.1.
RefSeqiNP_000210.2. NM_000219.5.
UniGeneiHs.121495.
Hs.745384.

Genome annotation databases

GeneIDi3753.
KEGGihsa:3753.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
BC046224 mRNA. Translation: AAH46224.1.
EF514883 mRNA. Translation: ABS84251.1.
EF514884 Genomic DNA. Translation: ABS84252.1.
AK313543 mRNA. Translation: BAG36319.1.
CR541756 mRNA. Translation: CAG46556.1.
RefSeqiNP_000210.2. NM_000219.5.
UniGeneiHs.121495.
Hs.745384.

3D structure databases

ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

STRINGi9606.ENSP00000337255.

Protein family/group databases

TCDBi8.A.10.1.2. the slow voltage-gated k+) channel accessory protein (mink) family.

Protocols and materials databases

DNASUi3753.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi3753.
KEGGihsa:3753.

Organism-specific databases

CTDi3753.
PharmGKBiPA211.

Phylogenomic databases

eggNOGiENOG410IY71. Eukaryota.
ENOG410Y1SF. LUCA.
HOVERGENiHBG052226.
KOiK04894.

Miscellaneous databases

ChiTaRSiKCNE1. human.
GenomeRNAii3753.

Family and domain databases

InterProiIPR000369. K_chnl_KCNE.
IPR005424. K_chnl_volt-dep_bsu_KCNE1.
[Graphical view]
PfamiPF02060. ISK_Channel. 1 hit.
[Graphical view]
PRINTSiPR01604. KCNE1CHANNEL.
PR00168. KCNECHANNEL.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FHJ6_HUMAN
AccessioniPrimary (citable) accession number: Q6FHJ6
Entry historyi
Integrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: June 8, 2016
This is version 85 of the entry and version 1 of the sequence. [Complete history]
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.