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Protein

Gamma-synuclein

Gene

SNCG

Organism
Homo sapiens (Human)
Status
Unreviewed-Annotation score: Annotation score: 2 out of 5-Experimental evidence at transcript leveli

Functioni

GO - Biological processi

Complete GO annotation...

Names & Taxonomyi

Protein namesi
Recommended name:
Gamma-synucleinUniRule annotation
Gene namesi
Name:SNCGImported
ORF Names:hCG_23263Imported
OrganismiHomo sapiens (Human)Imported
Taxonomic identifieri9606 [NCBI]
Taxonomic lineageiEukaryotaMetazoaChordataCraniataVertebrataEuteleostomiMammaliaEutheriaEuarchontogliresPrimatesHaplorrhiniCatarrhiniHominidaeHomo

Subcellular locationi

GO - Cellular componenti

Pathology & Biotechi

Organism-specific databases

PharmGKBiPA35989.

Expressioni

Gene expression databases

BgeeiENSG00000173267.
ExpressionAtlasiQ6FHG5. baseline and differential.

Interactioni

Protein-protein interaction databases

IntActiQ6FHG5. 1 interactor.
STRINGi9606.ENSP00000361087.

Structurei

3D structure databases

SMRiQ6FHG5.
ModBaseiSearch...
MobiDBiSearch...

Family & Domainsi

Sequence similaritiesi

Belongs to the synuclein family.UniRule annotation

Phylogenomic databases

eggNOGiENOG410IYGN. Eukaryota.
ENOG4111VY5. LUCA.
HOVERGENiHBG000481.
OMAiQANMVSD.
OrthoDBiEOG091G11PA.
PhylomeDBiQ6FHG5.

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002462. Synuclein_gamma.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01214. GSYNUCLEIN.
PR01211. SYNUCLEIN.

Sequencei

Sequence statusi: Complete.

Q6FHG5-1 [UniParc]FASTAAdd to basket

« Hide

        10         20         30         40         50
MDVFKKGFSI AKEGVVGAVE KTKQGVTEAA EKTKEGVMYV GAKTKENVVQ
60 70 80 90 100
SVTSVAEKTK EQANAVSEAV VSSVNTVATK TVEEAENIAV TSGVVRKEDL
110 120
RPSAPQQEGE ASKEKEEVAE EAQSGGD
Length:127
Mass (Da):13,331
Last modified:May 10, 2005 - v1
Checksum:iF183DEF302DBE688
GO

Experimental Info

Feature keyPosition(s)DescriptionActionsGraphical viewLength
Non-terminal residuei1Imported1
Non-terminal residuei127Imported1

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223367 mRNA. Translation: BAD97087.1.
AK312141 mRNA. Translation: BAG35077.1.
CR541788 mRNA. Translation: CAG46587.1.
CR541790 mRNA. Translation: CAG46589.1.
CH471142 Genomic DNA. Translation: EAW80316.1.
CH471142 Genomic DNA. Translation: EAW80317.1.
RefSeqiNP_003078.2. NM_003087.2.
UniGeneiHs.349470.

Genome annotation databases

GeneIDi6623.
KEGGihsa:6623.
UCSCiuc001keb.3. human.

Cross-referencesi

Sequence databases

Select the link destinations:
EMBLi
GenBanki
DDBJi
Links Updated
AK223367 mRNA. Translation: BAD97087.1.
AK312141 mRNA. Translation: BAG35077.1.
CR541788 mRNA. Translation: CAG46587.1.
CR541790 mRNA. Translation: CAG46589.1.
CH471142 Genomic DNA. Translation: EAW80316.1.
CH471142 Genomic DNA. Translation: EAW80317.1.
RefSeqiNP_003078.2. NM_003087.2.
UniGeneiHs.349470.

3D structure databases

SMRiQ6FHG5.
ModBaseiSearch...
MobiDBiSearch...

Protein-protein interaction databases

IntActiQ6FHG5. 1 interactor.
STRINGi9606.ENSP00000361087.

Protocols and materials databases

DNASUi6623.
Structural Biology KnowledgebaseSearch...

Genome annotation databases

GeneIDi6623.
KEGGihsa:6623.
UCSCiuc001keb.3. human.

Organism-specific databases

CTDi6623.
PharmGKBiPA35989.

Phylogenomic databases

eggNOGiENOG410IYGN. Eukaryota.
ENOG4111VY5. LUCA.
HOVERGENiHBG000481.
OMAiQANMVSD.
OrthoDBiEOG091G11PA.
PhylomeDBiQ6FHG5.

Miscellaneous databases

ChiTaRSiSNCG. human.
GenomeRNAii6623.

Gene expression databases

BgeeiENSG00000173267.
ExpressionAtlasiQ6FHG5. baseline and differential.

Family and domain databases

Gene3Di1.10.287.700. 1 hit.
InterProiIPR001058. Synuclein.
IPR002462. Synuclein_gamma.
[Graphical view]
PANTHERiPTHR13820. PTHR13820. 1 hit.
PfamiPF01387. Synuclein. 1 hit.
[Graphical view]
PRINTSiPR01214. GSYNUCLEIN.
PR01211. SYNUCLEIN.
ProtoNetiSearch...

Entry informationi

Entry nameiQ6FHG5_HUMAN
AccessioniPrimary (citable) accession number: Q6FHG5
Secondary accession number(s): A6NM47
Entry historyiIntegrated into UniProtKB/TrEMBL: May 10, 2005
Last sequence update: May 10, 2005
Last modified: January 18, 2017
This is version 102 of the entry and version 1 of the sequence. See complete history.
Entry statusiUnreviewed (UniProtKB/TrEMBL)
DisclaimerAny medical or genetic information present in this entry is provided for research, educational and informational purposes only. It is not in any way intended to be used as a substitute for professional medical advice, diagnosis, treatment or care.

Similar proteinsi

Links to similar proteins from the UniProt Reference Clusters (UniRef) at 100%, 90% and 50% sequence identity:
100%UniRef100 combines identical sequences and sub-fragments with 11 or more residues from any organism into one UniRef entry.
90%UniRef90 is built by clustering UniRef100 sequences that have at least 90% sequence identity to, and 80% overlap with, the longest sequence (a.k.a seed sequence).
50%UniRef50 is built by clustering UniRef90 seed sequences that have at least 50% sequence identity to, and 80% overlap with, the longest sequence in the cluster.